Results 181 to 190 of about 75,270 (295)

Hyperpolarized MRI in Oncology—A Review of Clinical Studies and Evaluation of Preclinical Liver Studies

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Hyperpolarized MRI is a promising clinical imaging modality in oncology, offering at least nine imaging contrasts obtainable with hyperpolarized [1‐13C]pyruvate as the injected agent, depending on the tissue and condition under investigation. Preclinical studies suggest that hyperpolarized MRI is warranted for detecting hepatocellular carcinoma within ...
Naama Lev‐Cohain, Jacob Sosna, Rachel Katz‐Brull   +2 more
wiley   +1 more source

Efficient Synthesis of Novel Propargyl Sulfamate Derivatives and Their Potent Inhibitory Effects on Human Carbonic Anhydrase Isoenzymes. [PDF]

ACS Omega
Atmaca U, Bayrak S, Bayrak C.
europepmc   +1 more source

Effects of Glyphosate on the Planktonic Microbiota: An Experimental Approach

Environmental Toxicology, Volume 41, Issue 10, Page 889-905, October 2026.
ABSTRACT Glyphosate is one of the most widely used herbicides in the world, including in Brazil, and its dispersion through habitats and surface waters can impact entire aquatic ecosystems. However, experimental studies evaluating the effects of pesticides on whole planktonic communities, considering attributes such as richness, density and composition—
Melissa Progênio, Matheus Henrique Oliveira de Matos, Edilaine Corrêa Leite, Bianca Ramos de Meira, João Vitor Bredariol, José Eduardo Gonçalves, Pablo Augusto Poleto Antiqueira, Luiz Felipe Machado Velho   +7 more
wiley   +1 more source

Design and Synthesis of Novel Bioactive Squamolone Derivatives Targeting Carbonic Anhydrase and Acetylcholinesterase Enzymes. [PDF]

ACS Omega
Koca İ, Çapan İ, Mehtap Özden E, Sert Y, Demir Y, Gülçin İ.   +5 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, Volume 41, Issue 10, Page 975-997, October 2026.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Investigating the Inhibitory Properties of Diazo and Pyrazole-Carboxamide-Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII. [PDF]

ChemMedChem
Akocak S, Lolak N, Ammara A, Gürbüz G, Bozgeyik I, Taşdemir D, Hashem H, Bräse S, Supuran CT.   +8 more
europepmc   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Targeting carbonic anhydrase IX-mediated ferroptosis by atractylenolide I alleviates DSS-induced colitis in mice. [PDF]

Front Pharmacol
Wang Y, Liang M, Guo H, Sun Z, Sun C, Chen M, Xu L.   +6 more
europepmc   +1 more source

Celebrating Rodolfo Margaria and applied physiology in Milan

Experimental Physiology, EarlyView.
Alberto E. Minetti, Gaspare Pavei, Damian M. Bailey   +2 more
wiley   +1 more source