Results 181 to 190 of about 77,334 (297)

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

open access: yesAdvanced Functional Materials, Volume 36, Issue 80, 5 October 2026.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang   +7 more
wiley   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen   +19 more
wiley   +1 more source

Synthesis, Moleculer Modeling, and Carbonic Anhydrase Inhibitor Effects of Novel 1‐(1‐benzyl‐2‐oxoindolin‐3‐ylidene)‐4‐(3‐sulfamoylphenyl)thiosemicarbazides [PDF]

open access: yesChemMedChem
Novel 1‐(1‐benzyl‐2‐oxoindolin‐3‐ylidene)thiosemicarbazides (6a–l) bearing a 3‐sulfamoylphenyl moiety selectively inhibited the tumor‐associated hCA IX and XII isoforms over hCA I and II isoforms at the nanomolar levels. Compounds 6k and 6f emerged as the most potent inhibitors of hCA IX and XII, respectively.
Apaydın Ç   +3 more
europepmc   +2 more sources

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

Depression and Anxiety After Topical Carbonic Anhydrase Inhibitors. [PDF]

open access: yesOphthalmol Sci
Elhusseiny AM, Alzein AF, Medeiros FA.
europepmc   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu   +6 more
wiley   +1 more source

Cultivation of Cladophora glomerata Under Low‐Salinity Conditions: Ecological Controls, Production Constraints and Baltic Sea Deployment

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
ABSTRACT Brackish and freshwater coastal systems often combine nutrient enrichment with proximity to wastewater, aquaculture and coastal infrastructure, yet macroalgal cultivation under low‐salinity conditions remains poorly validated. This review evaluates whether Cladophora glomerata, commonly managed as nuisance biomass, can be developed as a ...
Indrek Adler   +3 more
wiley   +1 more source

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