Computational and Experimental Characterization of <i>Mycobacterium marinum</i> β-Carbonic Anhydrase Inhibitors. [PDF]
Morshed N +3 more
europepmc +1 more source
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre +3 more
wiley +1 more source
Hyaluronic Acid-Palmitate Nanoparticle Delivery of Carbonic Anhydrase Inhibitors Impairs Growth and Early Metabolism in Escherichia coli Through β- and γ-Carbonic Anhydrase-Associated Processes. [PDF]
De Luca V +4 more
europepmc +1 more source
Flavodiiron proteins (FDPs) are di‐iron enzymes that reduce NO and/or O2 with distinct substrate selectivity. We have produced E. coli FDP variants targeting second coordination‐sphere residues and determined their structures. Although the kinetics remained unchanged, the E.
Patrícia T. Borges +8 more
wiley +1 more source
Porcine salivary carbonic anhydrase VI is involved in the pathogenesis of disease. [PDF]
Matas-Quintanilla M +3 more
europepmc +1 more source
Cryo‐EM reveals ArnA contamination during purification of a ciliary protein complex
ArnA contamination was independently observed during the purification of a soluble, low‐yield protein complex, leading to an unintended 3.23 Å resolution cryo‐EM structure. This work broadens recent findings and highlights ArnA as a recurrent His‐tag‐associated contaminant in Escherichia coli purification workflows.Endogenous Escherichia coli proteins ...
Xuguang Jiang, Masahide Kikkawa
wiley +1 more source
New Se-Compounds With Antileishmanial, Antitumor, and Carbonic Anhydrase Inhibitory Properties. [PDF]
Morán-Serradilla C +5 more
europepmc +1 more source
Perspectives for Advancing Biotechnological Succinic Acid Production
Succinic acid is an important molecule for sustainable chemical manufacturing, but its industrial production faces high costs and sustainability challenges, which are linked to feedstocks and excessive acid/base consumption. This opinion explores production routes based on next‐generation feedstocks and low‐pH fermentations to inspire novel cost ...
Christoph Gunkel, Bastian Blombach
wiley +1 more source
Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone-Based Derivatives. [PDF]
Sequeira L +13 more
europepmc +1 more source

