Results 141 to 150 of about 75,270 (295)

Treat Ankylosing Spondylitis with Methazolamide

International Journal of Medical Sciences, 2011
Background: Increased bone resorption and new bone information are two characteristics of ankylosing spondylitis (AS). Much evidence has shown that carbonic anhydrase inhibitors can restrain bone resorption.
Xiaotian Chang, Xinfeng Yan, Yunzhong Zhang
doaj  

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman, Hind Almushattat, Roselie M. H. Diederen, Tien‐En Tan, Peilun Dai, Coen de Vente, Daniel S. W. Ting, Maria M. van Genderen, Jeannette Ossewaarde‐van Norel, Redmer van Leeuwen, Martha J. H. Tjon‐Fo‐Sang, Clara I. Sánchez, M. Dominik Fischer, Maximilian Pfau, Jos W. R. Twisk, Camiel J. F. Boon   +15 more
wiley   +1 more source

ZIF-4 exhibiting high carbonic anhydrase-mimicking activities. [PDF]

RSC Adv
Zhang T, Qiu B, Lin X, Lei C.
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Clinical significance of carbonic anhydrase

, 2013
Práce je věnována anhydráze kyseliny uhličité, zejména výskytu a struktuře několika izoforem tohoto enzymu, se zaměřením na fyziologický a patologický význam v lidském organizmu.
Halbrštátová, Soňa
core   +1 more source

Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase. [PDF]

ChemMedChem
Pustenko A, Bobrovs R, Saravanan V, Avan K, Carradori S, Sizovs A, Angeli A, Supuran CT, Žalubovskis R.   +8 more
europepmc   +1 more source

Discovery of indolylchalcone benzenesulfonamides as selective inhibitors of tumor-associated carbonic anhydrase IX and XII. [PDF]

Sci Rep
Lee J, Biernacki K, Giovannuzzi S, Nada H, C Rivonker S, Kim C, Supuran CT, Elkamhawy A, Lee K.   +8 more
europepmc   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Synthesis and Biological Evaluation of Indole-Benzene Sulfonamides as Carbonic Anhydrase II, IX, and XII Inhibitors. [PDF]

ChemMedChem
Manasa V, Jayaprakash S, Paoletti N, Srikanth D, Tamang N, Soujanya D, Shaik MG, Yaddanapudi VM, Supuran CT, Nanduri S.   +9 more
europepmc   +1 more source

Gastric carbonic anhydrase [PDF]

The Journal of Physiology, 1939
openaire   +2 more sources