Results 31 to 40 of about 29,126 (284)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Carboniferous basement rocks of northern Britain [PDF]

open access: yes, 1987
The study of Carboniferous basement rocks of northern Britain has concentrated on the dominantly clastic rock succession which unconformably overlies the Lower Palaeozoic basement and occurs beneath the lowermost Carboniferous limestones in areas ...
Kimber, R.N, Kimber, Roger Neil
core  

Pseudogzheloceras—a new genus of Carboniferous nautilids (Cephalopoda) from Europe and North Africa

open access: yesGeo&Bio, 2021
Analysis of morphology, stratigraphic and geographic distribution of the group of nautilid species, mainly from the Westphalian of Western Europe, and the Bashkirian and Moscovian of the Donets Basin (Eastern Ukraine) made it possible to establish a new ...
V. Dernov
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Comparative analysis of paleoclimatic data for Carboniferous and Permian of the Kuznetsk Basin

open access: yesУчёные записки Казанского университета: Серия Естественные науки
This article presents the results of a comparative analysis of paleoclimatic data on the late Paleozoic of the Kuznetsk Basin. Using existing simulations of the Phanerozoic climate, Köppen–Geiger climate types were identified for eight time intervals ...
E. V. Karasev   +4 more
doaj   +1 more source

The relation of the “four properties” and fluid identification of the carboniferous weathering crust volcanic reservoir in the Shixi Oilfield, Junggar Basin, China

open access: yesFrontiers in Earth Science, 2022
This study addresses the poorly understood physical properties of the Shixi Oilfield reservoir, which consists of a weathered Carboniferous volcanic rocks with strong heterogeneity and in which logging identification and evaluation are difficult.
Lei Fu   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The anelastic structure and deep geology of the Derbyshire Dome from high frequency Rayleigh waves. [PDF]

open access: yes, 1984
This work is an investigation of the anelastic structure of the Derbyshire Dome and adjacent areas from the analysis of high frequency, 0.6 - 4.2 Hz, fundamental mode Rayleigh waves observed from quarry blasts within the study area.
McDonald, Andrew James William
core   +6 more sources

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