Results 41 to 50 of about 5,114 (260)

Differential characteristics of internal structures of strike-slip faults and their multiscale interactive identification mode: a case study of Carboniferous volcanic rocks in Chepaizi Uplift, Junggar Basin

open access: yesShiyou shiyan dizhi
Multi-phase transpressive strike-slip faults are well developed in the Carboniferous strata of the Chepaizi Uplift, Junggar Basin. These faults are characterized by severe weathering at the top, strong heterogeneity, poor stratification, and indistinct ...
Shiqi GUI   +7 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Paleopteran molecular clock: Time drift and recent acceleration

open access: yesEcology and Evolution
Applying BEAST v1.10.4, we constructed a Bayesian Inference tree comprising 322 taxa, primarily representing Paleoptera (Odonata and Ephemeroptera; Pterygota), Zygentoma and Archaeognatha (Apterygota; paraphyly), and Neoptera (Plecoptera; Pterygota ...
Soichi Osozawa, André Nel
doaj   +1 more source

Revision of the first Carboniferous palaeofloristic locality discovered in Argentina.

open access: yesActa Palaeobotanica, 2019
The first Carboniferous palaeofloristic locality recognized in Argentina is situated to the south of the Sierra Chica de Zonda in San Juan Province, Argentina.
GUSTAVO CORREA, SILVIA N. CÉSARI
doaj   +1 more source

Reservoir Formation Model and Main Controlling Factors of the Carboniferous Volcanic Reservoir in the Hong-Che Fault Zone, Junggar Basin

open access: yesEnergies, 2020
The Hong-Che Fault Zone is one of the important oil and gas enrichment zones in the Junggar Basin, especially in the Carboniferous. In recent five years, it has been proven that the Carboniferous volcanic rock has 140 million tons of oil reserves, and ...
Danping Zhu, Xuewei Liu, Shaobin Guo
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Formation mechanisms and distribution of weathered volcanic reservoirs: A case study of the carboniferous volcanic rocks in Northwest Junggar Basin, China

open access: yesEnergy Science & Engineering, 2020
In view of the complex reservoir heterogeneities within weathered volcanic rocks, taking the Carboniferous volcanic weathered profile reservoir of the northwest Junggar Basin as an example, this study aims to characterize weathered volcanic rocks by the ...
Cunhui Fan   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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