Results 61 to 70 of about 21,391 (306)

Reservoir Formation Model and Main Controlling Factors of the Carboniferous Volcanic Reservoir in the Hong-Che Fault Zone, Junggar Basin

open access: yesEnergies, 2020
The Hong-Che Fault Zone is one of the important oil and gas enrichment zones in the Junggar Basin, especially in the Carboniferous. In recent five years, it has been proven that the Carboniferous volcanic rock has 140 million tons of oil reserves, and ...
Danping Zhu, Xuewei Liu, Shaobin Guo
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Formation mechanisms and distribution of weathered volcanic reservoirs: A case study of the carboniferous volcanic rocks in Northwest Junggar Basin, China

open access: yesEnergy Science & Engineering, 2020
In view of the complex reservoir heterogeneities within weathered volcanic rocks, taking the Carboniferous volcanic weathered profile reservoir of the northwest Junggar Basin as an example, this study aims to characterize weathered volcanic rocks by the ...
Cunhui Fan   +5 more
doaj   +1 more source

The Carboniferous reefs in China

open access: yes, 2012
The Carboniferous period was a unique period for reef developments during the Late Paleozoic; however, in past years, studies dealing with the Carboniferous reefs in China were very rare.
Xiaohong, Chen   +5 more
core   +2 more sources

Review of the Devonian/Carboniferous Boundary in the Carnic Alps (Austria and Italy). [PDF]

open access: yes, 2019
In the Carnic Alps there are four sections exposing rocks across the Devonian–Carboniferous boundary: the Grüne Schneid and the Kronhofgraben sections in Austria, the Plan di Zermula A and the Sentiero per Cresta Verde sections in Italy.
CORRADINI C.   +23 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Comparative analysis of paleoclimatic data for Carboniferous and Permian of the Kuznetsk Basin

open access: yesУчёные записки Казанского университета: Серия Естественные науки
This article presents the results of a comparative analysis of paleoclimatic data on the late Paleozoic of the Kuznetsk Basin. Using existing simulations of the Phanerozoic climate, Köppen–Geiger climate types were identified for eight time intervals ...
E. V. Karasev   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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