Results 61 to 70 of about 29,126 (284)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Shiyou shiyan dizhiThe Carboniferous Kalashayi Formation in the southwestern Tarim Basin is a key target for Paleozoic hydrocarbon exploration in the Tarim Basin. Exploration results currently show marked spatial differences.
Fushun Zhang
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Geo&BioThe macroscopic remains of Carboniferous plants in the Donets Basin are represented by a variety of preservation types, including compressions, impressions, casts, as well as permineralised wood of gymnosperms preserved in alluvial and marine sandstones,
Vitaly Dernov, Halyna Anfimova
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
New paleopteran and polyneopteran insects from the Carboniferous of Northern France [PDF]
Acta Palaeontologica PolonicaTwo paleopteran and four polyneopteran insects are described from the Moscovian, Pennsylvanian, of coal slag heaps of Avion and Bruay-la-Bussière, Pas-de-Calais, Northern France, namely the spilapterid paleodictyopteran Spilaptera sp., Megasecoptera ...
Mathieu Boderau +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Carboniferous-Permian Transition
, 2013 Carboniferous; Permian ...
Spencer G. Lucas, William A. DiMichele, James E. Barrick, Joerg W. Schneider and Justin A. Spielmann
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source