Results 71 to 80 of about 94,162 (350)

A reconnaissance geochemical drainage survey of the Criffel-Dalbeattie granodiorite complex and its environs [PDF]

open access: yes, 1977
Regional geochemical reconnaissance by stream sediments and panned concentrates was undertaken over an area of 850 km 2 of south-west Scotland. Rocks of Ordovician to Permian age are exposed within the area but the major part is occupied by the ...
Brown, M.J.   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Western Irish Namurian Basin reassessed [PDF]

open access: yes, 2000
Current basin models for the Western Irish Namurian Basin (WINB) envisage an elongate trough along the line of the present-day Shannon Estuary that was infilled with clastic sediments derived from a hinterland that lay to the W or NW.
Best, J.L., Wignall, P.B.
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Reservoir Formation Model and Main Controlling Factors of the Carboniferous Volcanic Reservoir in the Hong-Che Fault Zone, Junggar Basin

open access: yesEnergies, 2020
The Hong-Che Fault Zone is one of the important oil and gas enrichment zones in the Junggar Basin, especially in the Carboniferous. In recent five years, it has been proven that the Carboniferous volcanic rock has 140 million tons of oil reserves, and ...
Danping Zhu, Xuewei Liu, Shaobin Guo
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Comparative analysis of paleoclimatic data for Carboniferous and Permian of the Kuznetsk Basin

open access: yesУчёные записки Казанского университета: Серия Естественные науки
This article presents the results of a comparative analysis of paleoclimatic data on the late Paleozoic of the Kuznetsk Basin. Using existing simulations of the Phanerozoic climate, Köppen–Geiger climate types were identified for eight time intervals ...
E. V. Karasev   +4 more
doaj   +1 more source

Formation mechanisms and distribution of weathered volcanic reservoirs: A case study of the carboniferous volcanic rocks in Northwest Junggar Basin, China

open access: yesEnergy Science & Engineering, 2020
In view of the complex reservoir heterogeneities within weathered volcanic rocks, taking the Carboniferous volcanic weathered profile reservoir of the northwest Junggar Basin as an example, this study aims to characterize weathered volcanic rocks by the ...
Cunhui Fan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Lead, zinc and copper mineralisation in basal Carboniferous sediments at Westwater, south Scotland [PDF]

open access: yes, 1977
A zioneo f lead, zinc and copperm ineralisatioins developedo ver a minimum I of 4 km of strikeo f basal Carboniferoucse mentstoneg roup sedimentsa nd immediatelyu nderlyingB irrenswarkL avas atwestwater,n ear Laqholm in south Scotland.
Davies, A.   +5 more
core  

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