Results 71 to 80 of about 21,391 (306)

K-feldspar sand-grain provenance in the Triassic, west of Shetland : distinguishing first-cycle and recycled sediment sources?

open access: yes, 2009
Sandstone provenance studies can help constrain palaeogeographic reconstructions and ancient drainage system scales and pathways. However, these insights can be obscured by difficulties in geochemically distinguishing or adequately characterising ...
Daly, J. Stephen   +9 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A stem of an arborescent lycopsid Sigillaria with attached rooting organs Stigmaria from the Pennsylvanian of the Donets Basin, eastern Ukraine

open access: yesGeo&Bio
The macroscopic remains of Carboniferous plants in the Donets Basin are represented by a variety of preservation types, including compressions, impressions, casts, as well as permineralised wood of gymnosperms preserved in alluvial and marine sandstones,
Vitaly Dernov, Halyna Anfimova
doaj   +1 more source

The Carboniferous-Permian Transition

open access: yes, 2013
Carboniferous; Permian ...
Spencer G. Lucas, William A. DiMichele, James E. Barrick, Joerg W. Schneider and Justin A. Spielmann
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

New paleopteran and polyneopteran insects from the Carboniferous of Northern France [PDF]

open access: yesActa Palaeontologica Polonica
Two paleopteran and four polyneopteran insects are described from the Moscovian, Pennsylvanian, of coal slag heaps of Avion and Bruay-la-Bussière, Pas-de-Calais, Northern France, namely the spilapterid paleodictyopteran Spilaptera sp., Megasecoptera ...
Mathieu Boderau   +2 more
doaj   +1 more source

Carboniferous-Permian Transition at Carrizo Arroyo, Central New Mexico

open access: yes, 2004
Carboniferous; Permian; Carboniferous-Permian; Carrizo Arroyo; New Mexico; Central New ...
Spencer G. Lucas and Kate E. Zeigler, eds.
core  

Polymetallic mineralisation in Carboniferous rocks at Hilderston, near Bathgate, central Scotland [PDF]

open access: yes, 1983
Five boreholes in the vicinity of the ancient Ag-Ni-Pb mine at Hilderston, near Bathgate have yielded new stratigraphic, mineralogical and geochemical information.
Stephenson, D.   +2 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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