Results 181 to 190 of about 552,882 (305)

Stereochemical Analysis of Tertiary Trifluoroacetamides Leveraging Both Through-Space ¹H···¹⁹F Spin-Spin Couplings and Anisotropic Solvent-Induced Shifts. [PDF]

J Org Chem
Watanabe K, Takano R, Tabata H, Hirano K, Iida M, Oshitari T, Natsugari H, Kusumi T, Nakamura K, Takahashi H.   +9 more
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Defect-Anchored Dipole Molecules Induce Surface Polarization Facilitating High-Performance Inverted Perovskite Solar Cells. [PDF]

Nanomicro Lett
Pan W, Wu J, Pan J, Wei S, Tan L, Li W, Wang D, Liu X, Xie Y, Lin J, Lan Z.   +10 more
europepmc   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

Advanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du, Eun Seo Bae, Thinh T. M. Bui, Seok Beom Lee, Dahan Kim, Jin‐Gyeong Park, Yongjoo Park, Soo Yeon Park, Sangwook Kang, Beomsu Lee, Daniel Shin, Yun Pyo Kang, In‐Gyun Lee, Dae‐Duk Kim, Seokhee Kim, Suckchang Hong, Kyuho Moon, Sang Kook Lee, Dong‐Chan Oh   +18 more
wiley   +1 more source

Electrochemical Generation of Ketyl Radicals and Their Applications

SynOpen
Zhoumei Tan, Kun Xu, Chengchu Zeng
doaj   +1 more source

Nickel-Catalyzed cine-Substitution Toward Carbonyl Dance. [PDF]

Chem Asian J
Moriya E, Muto K, Yamaguchi J.
europepmc   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

Advanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee, Donghoon Moon, Ziyan Qian, Jinwoo Kim, Changheon Kim, Yeojin Lee, Hyobin Yoo, Richard B. Wilson, Qiye Zheng, Gwan‐Hyoung Lee, Hyejin Jang   +10 more
wiley   +1 more source

Regioselectivity of the Reaction between β-Enamino Diketones and Methylhydrazine Explained. [PDF]

J Org Chem
Martinelli V, Leach IF, Poletto J, Richter WE, Rosa FA, Pontes RM.   +5 more
europepmc   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Carbonyl(h5-Cyclopentadienyl)(tetrafluoroborato)molybdenum and tungsten complexes [PDF]

, 1989
Beck, Wolfgang, Schloter, Klaus, Sünkel, Karlheinz, Urban, Günter   +3 more
core   +2 more sources