Results 191 to 200 of about 283,238 (267)

Programmable Functionalizations of Tetramethylpiperidine N-Oxyl (TEMPO)-Acrolein Linchpins Derived from Alkoxyallenes. [PDF]

J Am Chem Soc
Lee KS, Crawford CS, Cheng GT, Zerban JJ, Casali E, Panja S, Rampon DS, Schomaker JM.   +7 more
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Ring-Enlargement of in Situ Generated Cyclopropanones with Carbonyls and Imines: Synthesis of γ-Butyrolactones and -lactams. [PDF]

Org Lett
Lange M, Semmelmaier A, Herzog R, von Köller HF, Werz DB.   +4 more
europepmc   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Asymmetric Total Synthesis of C2-OH Lycopodium Alkaloids (-)-Palhinine B, (-)-Palhinine C, and (+)-Palhinine B Enabled by Stereocontrolled Diels-Alder Strategy. [PDF]

Org Lett
Pantawane A, Chen CM, Kuo TC, Reddy JS, Cheng MJ, Luo SY, Hsieh HP.   +6 more
europepmc   +1 more source

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

Advanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

NiH-Catalyzed Enantioconvergent α-Alkenylation of Carbonyl Compounds via Markovnikov Alkyne Hydronickellation. [PDF]

Angew Chem Int Ed Engl
Nam H, Jang S, Kim D, Seo S.
europepmc   +1 more source

D–A Type Perylene Micelles With Synergistic Charge/Energy Transfer for Dual‐Path ROS Generation and Enhanced Photocatalysis

Advanced Science, EarlyView.
Dual‐state activation of singlet and triplet excitons is achieved in perylene‐based nanomicelles via donor engineering. By synergistically pairing charge transfer with energy transfer pathways, while concurrently enabling pollutant pre‐enrichment, this strategy establishes spatial coupling between efficient ROS generation and rapid mineralization ...
Chenfan Xie, Jin Gao, Guan Wang, Xinyue Huang, Xinyi Hu, Lijun Zhu, Liujun Yang, Hua Li, Jianmei Lu   +8 more
wiley   +1 more source

Atmospheric Carbonyl Compounds at Shangdianzi, Beijing: Autumn-to-Winter Variation, Ozone Formation Potential, and Source Apportionment. [PDF]

Toxics
Song Y, Gao X, Li J, Wei S, Gong Y, Zhang H, Ren Y, Guo Y, Wang W, Li H, Ge M.   +10 more
europepmc   +1 more source

Infrared Spectra Prediction for a Carbonyl Group Utilizing a Graph Network Approach. [PDF]

Precis Chem
Shi J, Liu C, Mo F.
europepmc   +1 more source