Results 121 to 130 of about 129,195 (289)

Carboplatin combined with arsenic trioxide versus carboplatin combined with docetaxel treatment for LACC: A randomized, open-label, phase II clinical study

open access: yesOpen Medicine
This study compared the efficacy and safety of carboplatin combined with arsenic trioxide versus carboplatin combined with docetaxel in treating locally advanced cervical cancer (LACC).
Li Sijin   +6 more
doaj   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

open access: yesiNew Medicine, EarlyView.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu   +8 more
wiley   +1 more source

Stabilised Hyaluronic Acid Gel Rectal Spacers in MRI‐Guided Brachytherapy for Gynaecological Cancers: A Prospective Feasibility Study

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This prospective study investigated the feasibility of stabilised hyaluronic acid gel as a rectal spacer in gynaecological cancer brachytherapy. In twelve patients, the spacer was successfully inserted into the rectovaginal space without serious adverse events, had high visibility on MRI, increased the target‐to‐rectum distance compared with no spacer ...
Carminia Lapuz   +8 more
wiley   +1 more source

Inflammatory Markers may Determine Postoperative Complications in Cases of Peritoneal Carcinomatosis of Ovarian Origin Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives This study aimed to evaluate the ability of perioperative inflammatory markers to discriminate postoperative complications within 6 months in patients with ovarian cancer–related peritoneal metastasis undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Donmez Mustafa   +6 more
wiley   +1 more source

Prognostic Value of the C‐PLAN Index in Advanced Esophageal Squamous Cell Carcinoma Patients Treated With Immune Checkpoint Inhibitors

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the prognostic value of the C‐PLAN index in advanced esophageal squamous cell carcinoma (ESCC) patients receiving immune checkpoint inhibitor (ICI) therapy. A retrospective analysis of 241 eligible patients treated during February 2020 to January 2023 was conducted.
Yi Zhou   +5 more
wiley   +1 more source

Risk Factors Influencing Efficacy and Prognosis Evaluation of Neoadjuvant Systemic Therapy in Triple‐Positive Breast Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT To identify the determinants of the response to neoadjuvant systemic therapy (NST) in triple‐positive breast cancer (TPBC), we retrospectively enrolled 520 patients with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer who were treated at The First Affiliated Hospital of Chongqing Medical University between January 2015 ...
Lin‐Rui Miao   +7 more
wiley   +1 more source

Switching cisplatin to carboplatin in chemotherapy for metastatic penile cancer in a patient intolerant to cisplatin

open access: yesIJU Case Reports
Introduction Cisplatin is currently the key drug in the chemotherapy regimen for metastatic penile cancer. There are few reports of alternative medicines for patients who cannot tolerate cisplatin.
Keita Sekine   +9 more
doaj   +1 more source

Prognostic Value of Impaired Vocal Cord Mobility in T2N0 Glottic Cancer Treated With IMRT

open access: yesThe Laryngoscope, EarlyView.
T2N0M0 glottic cancers with impaired vocal cord mobility (VCM) have worse outcomes than T2N0M0 tumors with normal VCM, but still fare better than T3N0M0 disease. These findings support subdivision of T2 glottic cancer into T2a (normal VCM) and T2b (impaired VCM) in future TNM revisions.
Alexander Rühle   +20 more
wiley   +1 more source

FXTAS and the Spectrum of FMR1 Premutation‐Associated Phenotypes in Latin America: A Scoping Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative disorder caused by FMR1 premutation expansions (55–200 CGG repeats). Although well described in populations of predominantly European ancestry, FXTAS remains poorly characterized in Latin America due to limited awareness, restricted access to ...
Amy Schmidmajer   +6 more
wiley   +1 more source

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