Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
Neoadjuvant twelve weekly paclitaxel-carboplatin with trastuzumab and pertuzumab in HER2-positive breast cancer. [PDF]
Leshem Y +7 more
europepmc +1 more source
Summary Cytokine release syndrome (CRS) remains a major toxicity of chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL), and robust pre‐infusion predictors are needed for risk‐adapted management. We retrospectively analysed LBCL patients in the Japanese nationwide registry who underwent CD19 CAR‐T‐cell therapy between 2019 ...
Yasuyuki Arai +21 more
wiley +1 more source
Adjuvant capecitabine in women with triple-negative breast cancer with residual disease after carboplatin-containing neoadjuvant chemotherapy. [PDF]
Tavares GM +6 more
europepmc +1 more source
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel +31 more
wiley +1 more source
IMpower151: is this the final blow to PD-(L)1 inhibitors in metastatic, <i>EGFR</i>-mutant non-small-cell lung cancer? [PDF]
van Beusekom SAL +2 more
europepmc +1 more source
Objective To evaluate the concordance between clinical complete response (cCR) and pathological complete response (pCR) in muscle‐invasive bladder cancer (MIBC) to assess the surrogacy and prognostic value of cCR for guiding bladder‐sparing strategies.
Navid Roessler +15 more
wiley +1 more source
nab-paclitaxel/carboplatin induction in squamous NSCLC: Longitudinal quality of life while on chemotherapy [PDF]
et al,, Morgensztern, Daniel
core +1 more source
Top 5 Advances in the Last 50 Years: Malignant Gastric and Esophageal Surgery
World Journal of Surgery, EarlyView.
Luís Santos Castro, Lorenzo Ferri
wiley +1 more source
Malignant craniopharyngiomas: Institutional experience and literature review
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source

