Results 11 to 20 of about 129,195 (289)

Evaluation of bioabsorbable calcium sulfate hemihydrate beads for local delivery of carboplatin.

PLoS ONE, 2020
The objectives of this study were to evaluate a novel kit of resorbable calcium sulfate beads marketed specifically for use in veterinary medicine and generally used for local delivery of antimicrobials as carboplatin-delivery system.
Marine Traverson, Connor E Stewart, Mark G Papich   +2 more
doaj   +1 more source

Effect of CX3CL1/CX3CR1 gene polymorphisms on the clinical efficacy of carboplatin therapy in Han patients with ovarian cancer

Frontiers in Genetics, 2023
Gene polymorphisms have a close relationship with the clinical effects of carboplatin for ovarian cancer. Here, we investigated the relationship between CX3CL1 and CX3CR1 genotypes and the clinical efficacy of carboplatin in ovarian cancer, thereby ...
Xin-Chen Wang, Hong Zhou, Wen-Jing Jiang, Peng Jiang, Yan-Cai Sun, Wei-Jian Ni, Wei-Jian Ni   +6 more
doaj   +1 more source

In Vitro Chemosensitivity Using the Histoculture Drug Response Assay in Human Epithelial Ovarian Cancer [PDF]

, 2012
The choice of chemotherapeutic drugs to treat patients with epithelial ovarian cancer has not depended on individual patient characteristics. We have investigated the correlation between in vitro chemosensitivity, as determined by the histoculture drug ...
Kim, Dae-Yeon, Kim, Jong-Hyeok, Kim, Moon-Bo, Kim, Yong-Man, Kim, Young-Tak, Lee, Shin-Wha, Nam, Joo-Hyun   +6 more
core   +1 more source

Evaluation of Weight Change During Carboplatin Therapy in Dogs With Appendicular Osteosarcoma. [PDF]

, 2017
BackgroundThe prevalence of cancer cachexia in veterinary medicine has not been studied widely, and as of yet, no definitive diagnostic criteria effectively assess this syndrome in veterinary patients.Objectives(1) To determine the patterns of weight ...
Boston, SE, Culp, WTN, Kilkenny, JJ, Lu, X, Singh, A, Skorupski, KA, Story, AL, Woods, JP   +7 more
core   +1 more source

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results [PDF]

, 2016
Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after ...
De Felice, Francesca, Gravina, Giovanni Luca, Marampon, Francesco, Musio, Daniela, Tombolini, Vincenzo   +4 more
core   +7 more sources

Interaction Analysis of MRP1 with Anticancer Drugs Used in Ovarian Cancer: In Silico Approach

Life, 2022
Multidrug resistance (MDR) is one of the major therapeutic challenges that limits the efficacy of chemotherapeutic response resulting in poor prognosis of ovarian cancer (OC).
Absarul Haque, Ghazanfar Ali Baig, Abdulelah Saleh Alshawli, Khalid Hussain Wali Sait, Bilal Bin Hafeez, Manish Kumar Tripathi, Badrah Saeed Alghamdi, Hani S. H. Mohammed Ali, Mahmood Rasool   +8 more
doaj   +1 more source

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. [PDF]

, 2017
Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature.
Berry, Don, Brown-Swigart, Lamorna, Buxton, Meredith, DeMichele, Angela, Esserman, Laura, Glas, Annuska, Hirst, Gillian, Hylton, Nola, Linn, Sabine, Olopade, Olufunmilayo, Paoloni, Melissa, Petricoin, Emanuel, Rugo, Hope, Sanil, Ashish, Severson, Tesa M, Symmans, Fraser, van 't Veer, Laura, Wolf, Denise M, Wulfkuhle, Julia, Yau, Christina, Yee, Doug   +20 more
core   +2 more sources

Radiation therapy combined with intracerebral administration of carboplatin for the treatment of brain tumors [PDF]

, 2014
Background: In this study we determined if treatment combining radiation therapy (RT) with intracerebral (i.c.) administration of carboplatin to F98 glioma bearing rats could improve survival over that previously reported by us with a 15 Gy dose (5 Gy ...
Agius, Lawrence, Barth, Rolf F., Grecula, John C., Gupta, Nilendu, Huo, Tianyao, Nakkula, Robin J., Weldon, Michael, Yang, Weilian   +7 more
core   +2 more sources

Preclinical Studies Comparing Efficacy and Toxicity of DNA Repair Inhibitors, Olaparib, and AsiDNA, in the Treatment of Carboplatin-Resistant Tumors

Frontiers in Oncology, 2019
Purpose: Carboplatin is used to treat many cancers, but occurrence of drug resistance and its high toxicity remain a clinical hurdle limiting its efficacy.
Nirmitha I. Herath, Nirmitha I. Herath, Nirmitha I. Herath, Nirmitha I. Herath, Nathalie Berthault, Nathalie Berthault, Sylvain Thierry, Sylvain Thierry, Wael Jdey, Wael Jdey, Wael Jdey, Wael Jdey, Marie-Christine Lienafa, Marie-Christine Lienafa, Françoise Bono, Patricia Noguiez-Hellin, Jian-Sheng Sun, Marie Dutreix, Marie Dutreix   +18 more
doaj   +1 more source

Loss of REDD1 prevents chemotherapy‐induced muscle atrophy and weakness in mice

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Chemotherapy is an essential treatment to combat solid tumours and mitigate metastasis. Chemotherapy causes side effects including muscle wasting and weakness.
Brian A. Hain, Haifang Xu, David L. Waning   +2 more
doaj   +1 more source