Results 21 to 30 of about 2,651 (134)
Stereochemistry of Reactions Catalysed by Mammalian‐Brain
European Journal of Biochemistry, 1979 Deamination of 4‐aminobutyrate by mammalian or bacterial 4‐aminobutyrate aminotransferases involves the abstraction of the pro‐S hydrogen on C‐4 of 4‐aminobutyrate. Decarboxylation of L‐glutamate by rat brain glutamate decarboxylase occurs with retention of configuration. Inhibition of this enzyme by (S)‐4‐aminohex‐5‐ynoic acid involves the abstraction
M, Bouclier, M J, Jung, B, Lippert
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The FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
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The Role of APOBEC3B in Cancer: Mechanisms, Clinical Challenges, and Therapeutic Opportunities
Human Mutation, Volume 2026, Issue 1, 2026.Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 3B (APOBEC3B, A3B) is a key cytidine deaminase that induces genomic instability and clonal evolution in diverse malignancies. Although A3B plays a key role in the onset and advancement of various cancers, a comprehensive model bridging its multifaceted mechanisms and clinical translation ...
Fengfeng Zhou +3 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
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Anaerobic Limonene Metabolism in a Methanogenic Enrichment Involves a Glycine Radical Enzyme
Environmental Microbiology, Volume 27, Issue 11, November 2025.A methanogenic enrichment culture on the natural monoterpene limonene is characterised by a novel glycine radical enzyme for anaerobic hydrocarbon activation, the presence of a microbial loop for necromass utilisation and the presence of a predator of Bacteria and Archaea. ABSTRACT Limonene is a natural monoterpene omnipresent in human environments. It
Almud Lonsing +6 more
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Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial Biotechnology, Volume 18, Issue 11, November 2025.The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
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Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana
Advanced Science, Volume 12, Issue 39, October 20, 2025.Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang +9 more
wiley +1 more source
UEG Week 2025 Poster Presentations
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
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PROPERTIES OF CRYSTALLINE
Biochemical Journal, 1963 E M, WILSON, H L, KORNBERG
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Structural and functional insights into Uly1040, an ulvan lyase from polysaccharide lyase family 40. [PDF]
Appl Environ MicrobiolWang H-Q +9 more
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