Results 11 to 20 of about 2,660 (134)

Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics. [PDF]

open access: yesMicrob Biotechnol
This study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Mantegazza G   +5 more
europepmc   +2 more sources

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

open access: yesAngewandte Chemie, Volume 138, Issue 31, 27 July 2026.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti   +9 more
wiley   +2 more sources

Northeast China Traditional Kimchi (Paocai) Probiotic Resources Metabolized Uric Acid and Relieved Hyperuricemia in Mice

open access: yeseFood, Volume 7, Issue 4, August 2026.
Traditional fermented Kimchi “paocai”, commonly consumed in Northeast China, was screened for probiotic resources capable of degrading uric acid in vitro and alleviating hyperuricemia in a mouse model. Abstract Current pharmacological therapies for hyperuricemia (HUA), though effective, pose safety concerns, including allopurinol‐induced severe dermal ...
Aman Khan   +8 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, Volume 600, Issue 14, Page 2063-2076, July 2026.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3303-3319, June 2026.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa   +9 more
wiley   +1 more source

ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49‐MYB169 module

open access: yesNew Phytologist, Volume 250, Issue 6, Page 3747-3768, June 2026.
Summary Stone cells originate from secondary cell wall thickening and contain abundant lignin. Their excessive accumulation compromises pear fruit quality, yet the endogenous hormonal mechanisms governing stone cell formation remain unclear. Here, co‐expression network analysis using transcriptome data – the flesh of 206 sand pear accessions sampled at
Yanfei Shan   +10 more
wiley   +1 more source

Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition

open access: yesPlant, Cell &Environment, Volume 49, Issue 6, Page 3436-3454, June 2026.
ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng   +4 more
wiley   +1 more source

Oxalis corniculata L. Ethanol Extract Promotes Fracture Healing: Integrated Omics and Experimental Validation

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Oxalis corniculata L. ethanol extract (OCEE) showed efficacy in promoting fracture healing. A total of 549 compounds were identified by UHPLC‐Q‐Exactive‐MS/MS, with three key components recognized. OCEE may accelerate fracture healing by regulating TNFα, MMP9, ESR1, TP53, and related signaling pathways. ABSTRACT Oxalis corniculata L.
Jian Zhang   +5 more
wiley   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers   +16 more
wiley   +1 more source

Beyond the Enzyme‐Latch: A Narrative and Systematic Review of Enzymic Controls on Carbon Cycling in Peatlands

open access: yesGlobal Change Biology, Volume 32, Issue 5, May 2026.
Peatlands are vast carbon reservoirs, yet the processes that suppress plant‐matter decomposition and that can switch to carbon release under disturbance remain contested. One explanation is the Enzyme‐latch hypothesis, which proposes that enzymatic constraints ‘lock’ decomposition until peatlands are damaged.
Eleanor K. M. Birch, Nicholle G. A. Bell
wiley   +1 more source

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