Results 11 to 20 of about 2,651 (134)

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3303-3319, June 2026.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa   +9 more
wiley   +1 more source

ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49‐MYB169 module

open access: yesNew Phytologist, Volume 250, Issue 6, Page 3747-3768, June 2026.
Summary Stone cells originate from secondary cell wall thickening and contain abundant lignin. Their excessive accumulation compromises pear fruit quality, yet the endogenous hormonal mechanisms governing stone cell formation remain unclear. Here, co‐expression network analysis using transcriptome data – the flesh of 206 sand pear accessions sampled at
Yanfei Shan   +10 more
wiley   +1 more source

Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition

open access: yesPlant, Cell &Environment, Volume 49, Issue 6, Page 3436-3454, June 2026.
ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng   +4 more
wiley   +1 more source

Oxalis corniculata L. Ethanol Extract Promotes Fracture Healing: Integrated Omics and Experimental Validation

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Oxalis corniculata L. ethanol extract (OCEE) showed efficacy in promoting fracture healing. A total of 549 compounds were identified by UHPLC‐Q‐Exactive‐MS/MS, with three key components recognized. OCEE may accelerate fracture healing by regulating TNFα, MMP9, ESR1, TP53, and related signaling pathways. ABSTRACT Oxalis corniculata L.
Jian Zhang   +5 more
wiley   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers   +16 more
wiley   +1 more source

Beyond the Enzyme‐Latch: A Narrative and Systematic Review of Enzymic Controls on Carbon Cycling in Peatlands

open access: yesGlobal Change Biology, Volume 32, Issue 5, May 2026.
Peatlands are vast carbon reservoirs, yet the processes that suppress plant‐matter decomposition and that can switch to carbon release under disturbance remain contested. One explanation is the Enzyme‐latch hypothesis, which proposes that enzymatic constraints ‘lock’ decomposition until peatlands are damaged.
Eleanor K. M. Birch, Nicholle G. A. Bell
wiley   +1 more source

Porphyrins and porphyrinogen carboxy-lyase in hexachlorobenzene-induced porphyria [PDF]

open access: yesBiochemical Journal, 1977
1. Qualitative and quantitative studies of the porphyrins and the porphyrinogen carboxylyase of the liver, spleen, kidney, harderian gland and erythrocytes from normal rats and from those hexachlorobenzene-induced porphyria were carried out. 2. Hexachlorobenzene has no effect on erythrocyte porphyrin content, but produces a decrease in that of ...
L C, San Martín De Viale   +3 more
openaire   +2 more sources

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Global Advances in Hepatocellular Carcinoma Research and Therapy in 2025

open access: yesCancer Innovation, Volume 5, Issue 2, April 2026.
This review summarizes key breakthrough advances in hepatocellular carcinoma (HCC) reported in 2025 and presents a multidisciplinary management framework for HCC, integrating early diagnosis, microenvironment insights, and comprehensive therapeutic strategies spanning minimally invasive surgery, locoregional interventions, and systemic pharmacotherapy.
Bo Hu, Qiang Gao
wiley   +1 more source

Quinolone tolerance in Escherichia coli due to defects in the adenosine ribonucleotides de novo biosynthesis pathway

open access: yesmLife, Volume 5, Issue 2, Page 217-228, April 2026.
Abstract Central carbon metabolism is thought to link reactive oxygen species (ROS) with antibiotic‐mediated bacterial death. During enrichment screening of Escherichia coli with the first‐generation quinolone oxolinic acid, unstable antibiotic‐tolerant mutants containing deficiencies in purB were obtained.
Weiwei Zhu   +9 more
wiley   +1 more source

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