Results 111 to 120 of about 30,254 (254)

Regulation of the rat neutral cytosolic cholesteryl ester hydrolase promoter by hormones and sterols: a role for nuclear factor-Y in the sterol-mediated response

open access: yesJournal of Lipid Research, 1999
Expression of the rat liver neutral cytosolic cholesteryl ester hydrolase (CEH) gene is regulated by glucocorticoids, thyroxine, and agents that perturb cholesterol metabolism.
Ramesh Natarajan   +2 more
doaj   +1 more source

Dual-Purpose Inoculants and Their Effects on Corn Silage

open access: yesMicroorganisms, 2020
This study was conducted to screen dual-purpose lactic acid bacteria (LAB) from uncontrolled farm-scale silage, and then we confirmed their effects on corn silage.
Dimas Hand Vidya Paradhipta   +7 more
doaj   +1 more source

Regulation and structure of YahD, a copper-inducible α/β serine hydrolase of Lactococcus lactis IL1403 [PDF]

open access: yes, 2017
Lactococcus lactis IL1403 is a lactic acid bacterium that is used widely for food fermentation. Copper homeostasis in this organism chiefly involves copper secretion by the CopA copper ATPase.
Mancini, Stefano   +5 more
core  

Bisphenol A‐associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver [PDF]

open access: yes, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106679/1/em21823 ...
Dolinoy, Dana C.   +3 more
core   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao   +4 more
wiley   +1 more source

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells

open access: yesMolecules, 2018
Herb-drug interactions are important safety concerns in clinical practice. The interactions occur firstly in the intestinal absorption for orally administered drugs.
Zongxi Sun   +7 more
doaj   +1 more source

QuaDMutEx: quadratic driver mutation explorer [PDF]

open access: yes, 2017
Background Somatic mutations accumulate in human cells throughout life. Some may have no adverse consequences, but some of them may lead to cancer. A cancer genome is typically unstable, and thus more mutations can accumulate in the DNA of cancer cells ...
Arodz, Tomasz Jakub, Yahya, Bokhari
core   +1 more source

Purification and characterisation of a carboxylesterase from the latex ofSynadenium grantii Hook, ‘f’ [PDF]

open access: yes, 1987
The latex ofSynadenium grantii was found to contain esterolytic activity. Polyacrylamide gel electrophoretic study coupled with substrate and inhibitor specificity studies revealed the presence of multiple forms of carboxylesterases and cholinesterases ...
Govardhan,, L.   +3 more
core   +1 more source

Different methods to counteract mycotoxin production and its impact on animal health [PDF]

open access: yes, 2013
Mycotoxins can cause serious adverse effects on animal health. This may lead to great economic losses in animal husbandry. In this review, the most common methods to counteract mycotoxins are presented, including several pre- and post-harvest strategies ...
Croubels, Siska   +2 more
core   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

open access: yes, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Akada   +119 more
core   +1 more source

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