Results 91 to 100 of about 18,753 (228)
Evolutionary Applications, Volume 19, Issue 11, November 2026.ABSTRACT The redlegged earth mite, Halotydeus destructor, is an invasive pest of grain and pasture crops in Australia. Australian populations are increasingly developing resistance to broad‐spectrum pesticides. Here, we assembled a chromosome‐level genome for H. destructor, comprising nine chromosomes and totalling approximately 46 Mb.
Joshua A. Thia +14 more
wiley +1 more source
, 2023 Pancreatic ductal adenocarcinoma is an aggressive form of cancer, with low patient survival rates. Irinotecan, a key chemotherapeutic drug, is activated by carboxylesterase 2, which has been established as a predictive and prognostic biomarker of patient
Kailass, Karishma
core +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
Enzymatic determination of α-aminophosphonates with butyryl cholinesterase and carboxylesterase [PDF]
, 1999 The analytical characteristics of the determination of α-aminophosphonates were studied using butyryl cholinesterase from horse serum and microbial carboxylesterase stabilized by incorporation in water-soluble N-phthalylchitosan-based polymeric films. It
Stoikov I. +5 more
core
Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat
Journal of Lipid Research, 2009 Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of the effects of moderate aerobic training on their expression using a rat model.
Rita Romani +8 more
doaj +1 more source
, 2022 Highly enantioselective lipase has been widely utilized in the preparation of versatile enantiopure chiral sec-alcohols through kinetic or dynamic kinetic resolution.
Seongsoon Park (3195249) +3 more
core +1 more source
Cutinase and Other Lipolytic Esterases Protect Bean Leaves from Infection by Rhizoctonia solani
Molecular Plant-Microbe Interactions, 1998 The results describe a novel activity of fungal cutinase, the protection of bean leaves from disease. Development of web blight symptoms on bean leaves infected with Rhizoctonia solani (AG-1) was prevented in the presence of cutinase purified from ...
Diana M. Parker, Wolfram Köller
doaj +1 more source
Carboxylesterase 1 genes:systematic review and evaluation of existing genotyping procedures [PDF]
, 2018 The carboxylesterase 1 gene (CES1) encodes a hydrolase that metabolizes commonly used drugs. The CES1-related pseudogene, carboxylesterase 1 pseudogene 1 (CES1P1), has been implicated in gene exchange with CES1 and in the formation of hybrid genes ...
Henrik Berg Rasmussen +3 more
core +1 more source
Pharmaceutics, 2013 The use of a prodrug, a conjugate of an active drug with a lipophilic substituent, is a good way of increasing the cutaneous absorption of a drug. However, the activity of dermal hydrolases has rarely been investigated in humans, or experimental animals.
Harunobu Iwase +3 more
doaj +1 more source
Enzymatic determination of α-aminophosphonates with butyryl cholinesterase and carboxylesterase
, 2020 The analytical characteristics of the determination of α-aminophosphonates were studied using butyryl cholinesterase from horse serum and microbial carboxylesterase stabilized by incorporation in water-soluble N-phthalylchitosan-based polymeric films. It
Stoikov I. +5 more
core