Results 141 to 150 of about 30,254 (254)

A dysregulation in CES1, APOE and other lipid metabolism-related genes is associated to cardiovascular risk factors linked to obesity [PDF]

, 2010
OBJECTIVE: The aim of the present study was to investigate the relationship between the differential expression of genes related to lipid metabolism in subcutaneous adipose tissue and metabolic syndrome features in lean and obese subjects with ...
Gonzalez-Muniesa, P. (Pedro), Marrades, M.P. (María Pilar), Martinez, J.A. (José Alfredo), Moreno-Aliaga, M. J. (María Jesús)   +3 more
core  

Carboxylesterase [PDF]

, 2020
openaire   +1 more source

Clinical pharmacokinetics and metabolism of irinotecan (CPT-11) [PDF]

, 2001
CPT-11 belongs to the class of topoisomerase I inhibitors, and it acts as a prodrug of SN-38, which is approximately 100-1000-fold more cytotoxic than the parent drug.
Alphen, R.J. (Robbert) van, Loos, W.J. (Walter), Mathijssen, A.H.J. (Ron), Nooter, K. (Kees), Sparreboom, A. (Alex), Stoter, G. (Gerrit), Verweij, J. (Jaap)   +6 more
core  

Kinetic analysis suggests that malathion at low environmental exposures is not toxic to humans. [PDF]

PLoS One
Schopfer LM, Tacal O, Masson P, Lockridge O.   +3 more
europepmc   +1 more source

Transcriptome and Functional Analyses Revealed the Carboxylesterase Genes Involved in Pyrethroid Resistance in <i>Anopheles sinensis</i> (Diptera: Culicidae). [PDF]

Insects
Wei Y, Gu X, Si F, Chen X, Qiao L, Yan H, Chen B.   +6 more
europepmc   +1 more source

Ester Prodrug NLRP3 Inflammasome Inhibitor NT-0796 is Brain Active due to Activation by Local Expression of Carboxylesterase-1. [PDF]

ACS Chem Neurosci
Digby Z, Diamond C, Wescott H, Smolak P, Thornton P, Lindsay N, Gabel CA, Clarke N, Watt AP.   +8 more
europepmc   +1 more source

Loss of hepatic carboxylesterase 3 prevents the development of MASLD in mice. [PDF]

J Lipid Res
Batayneh Z, Pan X, Gopoju R, Hu S, Chen S, Wang J, Wang H, Gunawardana L, Kasumov T, Zhang Y.   +9 more
europepmc   +1 more source

Integrated Gut Microbiota-Drug Interaction Analysis and Network Pharmacology for the Investigation of Renal-Protective Effect of <i>Polygala tenuifolia</i> Willd. [PDF]

Int J Mol Sci
Hu JC, Song JY, Feng R, Ye ML, Xu H, Lu JY, Zuo HT, Zhao Y, Wang JY, Jin JY, Wei LY, Tu YM, Wang Y.   +12 more
europepmc   +1 more source

Mosquito Carboxylesterase Estα21 (A2). [PDF]

Journal of Biological Chemistry, 1995
Ashley Vaughan, Janet Hemingway
openaire   +1 more source

CES3 promotes NSCLC progression via lipid metabolic reprogramming regulated by TFAP2A. [PDF]

J Cancer
Luo P, Huang Z, Ding S, Tang Z, Wei Y, Jiang S, Tang R, Li F, Yang H, Zhao L.   +9 more
europepmc   +1 more source