Results 1 to 10 of about 5,409,760 (241)

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties

open access: yesJournal of chemistry, 2022
Lead optimization represents the tedious process of fine-tuning lead compounds from biologically active hits to suitable drug candidates for clinical trials.
Kato Bredael   +4 more
semanticscholar   +1 more source

Interfacial and Internal Proton Conduction of Weak-acid Functionalized Styrene-based Copolymer with Various Carboxylic Acid Concentrations

open access: yesElectrochemistry, 2021
Investigation of interfacial proton transport is necessary to elucidate biological systems. As commonly found in biomaterials, the carboxylic acid group was proven to act as a proton-conducting group.
Athchaya SUWANSOONTORN   +4 more
doaj   +1 more source

Synthesis and Characterization of Some New Coumarin Derivatives as Probable Breast Anticancer MCF-7 Drugs

open access: yesCrystals, 2021
This study aimed to synthesize quinolinone derivatives and investigate their cytotoxic activity. The compound 1-azacoumarin-3-carboxylic acid (2-oxo-1H-quinoline-3-carboxylic acid) was obtained via the cyclocondensation of 2-hydroxybenzaldehyde with ...
Ahmed Gaber   +5 more
doaj   +1 more source

Crystal structure of 2,5-dihydroxyterephthalic acid from powder diffraction data

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2022
The crystal structure of anhydrous 2,5-dhydroxyterephthalic acid, C8H6O6, was solved and refined using laboratory X-ray powder diffraction data, and optimized using density functional techniques.
Joshua D. Vegetabile, James A. Kaduk
doaj   +1 more source

(η5-Carboxycyclopentadienyl)(η7-cycloheptatrienyl)manganese(I) hexafluoridophosphate

open access: yesIUCrData, 2023
The title compound, [Mn(C7H7)(C6H5O2)]PF6 or [(Cht)Mn(Cp'CO2H)]PF6, with Cht = cycloheptatrienyl and Cp' = C5H4, is an air-stable, purple, heteroleptic, cationic sandwich complex with manganese in oxidation state +I and π-coordinating cycloheptatrienyl ...
Reinhard Thaler   +2 more
doaj   +1 more source

General Method to Increase Carboxylic Acid Content on Nanodiamonds

open access: yesMolecules, 2022
Carboxylic acid is a commonly utilized functional group for covalent surface conjugation of carbon nanoparticles that is typically generated by acid oxidation.
Ganesh Shenoy   +11 more
doaj   +1 more source

Structure-antioxidant activity relationship of methoxy, phenolic hydroxyl, and carboxylic acid groups of phenolic acids

open access: yesScientific Reports, 2020
The antioxidant activities of 18 typical phenolic acids were investigated using 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) assays.
Jinxiang Chen   +5 more
semanticscholar   +1 more source

Electrosynthesis Using Carboxylic Acid Derivatives: New Tricks for Old Reactions.

open access: yesAccounts of Chemical Research, 2020
Electrosynthetic organic chemistry is an old discipline that takes its root in Faraday's seminal works. The field has a rich history and is in the midst of a renaissance, due to the growing impetus of the chemical community to develop greener, more ...
M. Leech, K. Lam
semanticscholar   +1 more source

Study of the effect of microwave-ray on some carboxylic acids containing hydroxyl group at α – carbon [PDF]

open access: yesمجلة التربية والعلم, 1999
: The effect of Microwave-ray was studied on the three mono carboxylic acids contains hydroxyl group (OH) at α – carbon in the solid state at different times. these carboxylic acids are Glycolic acid, Mandilic acid, Benzilic acid.
Ahmed Sadoon
doaj   +1 more source

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