Lipase Enzyme for Biomass Valorization
Chemistry Proceedings, 2022 Lipase enzymes are part of the hydrolases family acting on carboxylic ester bonds [...]
Madalina Tudorache
doaj +1 more source
Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media
Microorganisms, 2022 The thermoalkalophilic membrane-associated esterase E34Tt from Thermus thermophilus HB27 was cloned and expressed in Kluyveromyces lactis (KLEST-3S esterase). The recombinant enzyme was tested as a biocatalyst in aqueous and organic media. It displayed a
Roberto González-González +8 more
doaj +1 more source
Industrial applications of fungal lipases: a review
Frontiers in Microbiology, 2023 Fungal lipases (triacylglycerol acyl hydrolases EC 3.1.1.3) are significant industrial enzymes and have several applications in a number of industries and fields. Fungal lipases are found in several species of fungi and yeast.
Ashish Kumar +6 more
doaj +1 more source
Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes: implications for classification of enzyme function. [PDF]
PLoS Computational Biology, 2010 Functionally analogous enzymes are those that catalyze similar reactions on similar substrates but do not share common ancestry, providing a window on the different structural strategies nature has used to evolve required catalysts.
Daniel E Almonacid +3 more
doaj +1 more source
Comparative Investigation of Cytotoxic Effects of Structurally Diverse Small Molecules and In Silico Analysis of 1-Acetyl-4-(4-Hydroxyphenyl)piperazine. [PDF]
J Cell Mol MedABSTRACT This study assessed the anticancer activity of boron‐containing and structurally diverse small molecules in 4T1 breast cancer and Caco‐2 colon adenocarcinoma cells. Initial screening showed that five boronic acids lacked significant cytotoxicity, underscoring the structural specificity required for boron‐mediated bioactivity.
Yerlikaya A, Tümer E, Güzel M.
europepmc +2 more sources
Frontiers in Microbiology, 2020 Biodegradation of synthetic polymers, in particular polyethylene terephthalate (PET), is of great importance, since environmental pollution with PET and other plastics has become a severe global problem. Here, we report on the polyester degrading ability
Alexander Bollinger +13 more
doaj +1 more source
Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases. [PDF]
Angew Chem Int Ed EnglAlcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Damian M +4 more
europepmc +3 more sources
Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]
, 2004 BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M +4 more
core +2 more sources
Lipase catalysed kinetic resolutions of 3-aryl alkanoic acids [PDF]
, 2011 Hydrolase catalysed kinetic resolutions leading to a series of 3-aryl alkanoic acids (≥94% ee) is described. Hydrolysis of the ethyl esters with a series of hydrolases was undertaken to identify biocatalysts that yield the corresponding acids with ...
Brossat, Maude +3 more
core +1 more source
Biochemical studies on a versatile esterase that is most catalytically active with polyaromatic esters [PDF]
, 2014 M-E.G. thanks the CSIC for a JAE-Doc fellowship and the National Council for Scientific and Technological Development of Brazil (CNPq) for a BJT grant (Process number 370630/2013-0). I.L.
Bargiela, Rafael +8 more
core +1 more source