Results 1 to 10 of about 27,225 (279)

Purification of a chymotrypsin-like enzyme present on adult Schistosoma mansoni worms from infected mice and its characterization as a host carboxylesterase [PDF]

open access: green, 2016
A serine protease-like enzyme found in detergent extracts of Schistosoma mansoni adult worms perfused from infected mice has been purified from mouse blood and further characterized.
Doenhoff, Michael J.   +3 more
core   +4 more sources

Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B [PDF]

open access: goldPathogens, 2021
Bioinformatics analysis of the complete transcriptome of Fasciola hepatica, identified a total of ten putative carboxylesterase transcripts, including a 3146 bp mRNA transcript coding a 2205 bp open reading frame that translates into a protein of 735 ...
Yaretzi J. Pedroza-Gómez   +7 more
doaj   +2 more sources

Retracted: Comparative molecular docking and molecular‐dynamic simulation of wild‐type‐ and mutant carboxylesterase with BTA‐hydrolase for enhanced binding to plastic

open access: goldEngineering in Life Sciences, 2022
According to the literature review, microbial degradation of polyethylene terephthalate by PETases has been detected effective and eco‐friendly. However, the number of microorganisms capable of such feats is limited with some undesirable bioprospecting ...
Fatana Lameh   +2 more
doaj   +2 more sources

Dimethyl Fumarate vs. Monomethyl Fumarate: Unresolved Pharmacologic Issues [PDF]

open access: yesPharmaceutics
Dimethyl fumarate (DMF) has established a significant position among therapies for multiple sclerosis and psoriasis and is now being investigated for repurposing to many other non-malignant diseases.
Jana Kopincova, Iveta Bernatova
doaj   +2 more sources

Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pump [PDF]

open access: hybridJournal of Lipid Research, 2012
Z-Guggulsterone is a major ingredient in the Indian traditional hypolipidemic remedy guggul. A study in mice has established that its hypolipidemic effect involves the farnesoid X receptor (FXR), presumably by acting as an antagonist of this receptor. It
Dongfang Yang   +7 more
doaj   +2 more sources

Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs [PDF]

open access: yesMolecular Therapy: Nucleic Acids, 2013
MGH2.1 is a herpes simplex virus type 1 (HSV1) oncolytic virus that expresses two prodrug-activating transgenes: the cyclophosphamide (CPA)-activating cytochrome P4502B1 (CYP2B1) and the CPT11-activating secreted human intestinal carboxylesterase (shiCE).
Kazue Kasai   +9 more
doaj   +4 more sources

Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance

open access: yesCell Reports, 2017
Serine hydrolases are a large family of multifunctional enzymes known to influence obesity. Here, we performed activity-based protein profiling to assess the functional level of serine hydrolases in liver biopsies from lean and obese humans in order to ...
Julie Massart   +2 more
exaly   +3 more sources

Carboxylesterase from edible legume seeds and their sensitivity to organophosphate and carbamate pesticides

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2023
Carboxylesterase from edible legume seeds, including black gram bean (Vigna mungo (L.) Hepper), mung bean (Vigna radiata (L.) Wilczek) and red bean (Vigna umbellata (Thunb.) Ohwi and Ohashi) has been partially purified using the ammonium sulphate ...
Chiradet NASUK   +2 more
doaj   +1 more source

Lipolytic Activity of a Carboxylesterase from Bumblebee (Bombus ignitus) Venom

open access: yesToxins, 2021
Bee venom is a complex mixture composed of peptides, proteins with enzymatic properties, and low-molecular-weight compounds. Although the carboxylesterase in bee venom has been identified as an allergen, the enzyme’s role as a venom component has not ...
Yijie Deng   +7 more
doaj   +1 more source

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