Results 11 to 20 of about 27,225 (279)
Carboxylesterase inhibitors [PDF]
Expert Opinion on Therapeutic Patents, 2011 Carboxylesterases play major roles in the hydrolysis of numerous therapeutically active compounds. This is, in part, due to the prevalence of the ester moiety in these small molecules. However, the impact these enzymes may play on drug stability and pharmacokinetics is rarely considered prior to molecule development.
M Jason, Hatfield, Philip M, Potter
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Molecules, 2022 Acetyl xylan esterases (AXEs) are enzymes capable of hydrolysing the acetyl bonds in acetylated xylan, allowing for enhanced activity of backbone-depolymerizing enzymes.
Henry Madubuike, Natalie Ferry
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Environmental role of aromatic carboxylesterases [PDF]
Environmental Microbiology, 2021 Summary The carboxylesterases (EC 3.1.1.x) are widely distributed and form an important yet diverse group of hydrolases catalysing the ester bond cleavage in a variety of substrates. Besides acting on plant cell wall components like cutin, tannin and feruloyl esters, they are often the first line of defence to metabolize drugs ...
Venkatesh M. Ghodke, Narayan S. Punekar
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A Fast-Response AIE-Active Ratiometric Fluorescent Probe for the Detection of Carboxylesterase
Biosensors, 2022 Hepatocellular carcinoma (HCC) is associated with a high mortality rate worldwide. The therapeutic outcomes can be significantly improved if diagnosis and treatment are initiated earlier in the disease process.
Mengting Xia +6 more
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Frontiers in Physiology, 2021 Insects rely on their olfactory systems in antennae to recognize sex pheromones and plant volatiles in surrounding environments. Some carboxylesterases (CXEs) are odorant-degrading enzymes (ODEs), degrading odorant signals to protect the olfactory ...
Jiankun Yi +14 more
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Toxins, 2023 Fumonisins (FBs) are mycotoxins that threaten public health and food safety worldwide. Enzymatic degradation of Fumonisin B1 (FB1) through decarboxylation has attracted much attention, whereas application of FB1 carboxylesterase in detoxification ...
Lixiang Jiang +6 more
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CARBOXYLESTERASES IN ENANTIOSELECTIVE SYNTHESIS OF ORGANIC COMPOUNDS [PDF]
Biotechnologia Acta, 2013 The classification, structure, and mechanism of catalytic action of carboxylesterase of different origin are presented in the review. The prospects of carboxylesterases application for metabolism and both several drugs and prodrugs activation ...
E. A. Shesterenko +3 more
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Heterologous expression of salt-tolerant carboxylesterase Est40 in Escherichia coli and fermentation conditions optimization [PDF]
Zhongguo niangzaoThe encoding gene of the salt-tolerant carboxylesterase Est40 from the halophilic bacterium Vreelandella sp. CH40 was obtained through artificial synthesis technology.
LV Jiaxuan, TAO Yujie, WANG Rong, ZHU Derui, XING Jiangwa
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Biodegradation of malathion by Bacillus licheniformis strain ML-1 [PDF]
Archives of Biological Sciences, 2016 Malathion, a well-known organophosphate pesticide, has been used in agriculture over the last two decades for controlling pests of economically important crops.
Khan Sara +8 more
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Frontiers in Physiology, 2022 The wood-boring beetles, including the majority of Cerambycidae, have developed the ability to metabolize a variety of toxic compounds derived from host plants and the surrounding environment.
An-Jin Yang +8 more
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