Results 11 to 20 of about 18,753 (228)
Scientific Reports, 2017 The EstPS1 gene, which encodes a novel carboxylesterase of Pseudomonas synxantha PS1 isolated from oil well-produced water, was cloned and sequenced.
Xianghai Cai +7 more
doaj +2 more sources
A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in
BMC Biology, 2012 Background Insects respond to the spatial and temporal dynamics of a pheromone plume, which implies not only a strong response to 'odor on', but also to 'odor off'. This requires mechanisms geared toward a fast signal termination.
Chertemps Thomas +6 more
doaj +2 more sources
Enhancement of Cytosolic Carboxylesterase by Phenobarbital in the Rat
, 1978 Previously suggested identity of soluble hepatic carboxylesterase and cytosolic aldehyde dehydrogenase was studied in the liver of the rr and RR rat substrains after phenobarbital administration. Results showed over 30% increase of carboxylesterase activity in all animals treated with phenobarbital.
Nousiainen, U. +2 more
openaire +4 more sources
Biochemical and Biophysical Research Communications, 1975 During the final stage of purification of pig liver carboxylesterase on CM-Sephadex, several enzyme activities are present in addition to the pig liver carboxylesterase reported from this laboratory (Horgan et al., 1969a). Variation in substrate specificity and specific activity of the material isolated from CM-Sephadex has been analysed with four ...
Hamilton S.E. +3 more
openaire +5 more sources
Rational Engineering of a Carboxylesterase for the Synthesis of Polyesters for Biomedical Applications [PDF]
, 2021 Reengineered variants of a hyperthermophilic carboxylesterase with improved product yield in the synthesis of poly(ε-caprolactone) and triblock poly(ε-caprolactone)-co-poly(ethylene glycol)Methods: Quantum Mechanics/Molecular Mechanics Molecular ...
Derek J., Quinn +8 more
core +2 more sources
Carboxylesterase inhibitors [PDF]
Expert Opinion on Therapeutic Patents, 2011 Carboxylesterases play major roles in the hydrolysis of numerous therapeutically active compounds. This is, in part, due to the prevalence of the ester moiety in these small molecules. However, the impact these enzymes may play on drug stability and pharmacokinetics is rarely considered prior to molecule development.
M Jason, Hatfield, Philip M, Potter
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Human Carboxylesterase 2 in Cocaine Metabolism [PDF]
, 2021 Increased hydrolysis of cocaine to non-toxic compounds is a promising way to prevent cocaine-induced toxicity. However, the short half-life of cocaine in the blood and the rapid conversion in the body to the hydrolysis-resistant metabolite ...
Alexandra T.P., Carvalho +2 more
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Environmental role of aromatic carboxylesterases [PDF]
Environmental Microbiology, 2021 Summary The carboxylesterases (EC 3.1.1.x) are widely distributed and form an important yet diverse group of hydrolases catalysing the ester bond cleavage in a variety of substrates. Besides acting on plant cell wall components like cutin, tannin and feruloyl esters, they are often the first line of defence to metabolize drugs ...
Venkatesh M. Ghodke, Narayan S. Punekar
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Carbon nanomaterial functionalization with pesticide-detoxifying carboxylesterase [PDF]
, 2022 Four carbon materials, spent coffee-ground biochar, carbon black, short CNTs, and nitrogen-doped few-layer graphene (N-graphene) were tested for their functionalization with a commercial carboxylesterase.
Dondero, F +6 more
core +1 more source
Secreted and tumour targeted human carboxylesterase for activation of irinotecan [PDF]
, 2002 Innotecan (CPT-II) is an anticancer agent for the treatment of colon cancer. CPT-II can be considered as a prodrug, since it needs to be activated into the toxic drug SN-38 by the enzyme carboxylesterase. An approach to achieve tumour specific activation
Sone, T +16 more
core +1 more source