Results 11 to 20 of about 17,229 (228)
A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in
BMC Biology, 2012 Background Insects respond to the spatial and temporal dynamics of a pheromone plume, which implies not only a strong response to 'odor on', but also to 'odor off'. This requires mechanisms geared toward a fast signal termination.
Chertemps Thomas +6 more
doaj +3 more sources
Catabolism of strigolactones by a carboxylesterase [PDF]
Nature Plants, 2021 Strigolactones (SLs) are carotenoid-derived plant hormones that control shoot branching and communications between host plants and symbiotic fungi or root parasitic plants. Extensive studies have identified the key components participating in SL biosynthesis and signalling, whereas the catabolism or deactivation of endogenous SLs in planta remains ...
Enjun Xu +6 more
openaire +4 more sources
Improved Production of Recombinant Carboxylesterase FumDM by Co-Expressing Molecular Chaperones in Pichia pastoris [PDF]
Toxins, 2023 Fumonisins (FBs) are mycotoxins that threaten public health and food safety worldwide. Enzymatic degradation of Fumonisin B1 (FB1) through decarboxylation has attracted much attention, whereas application of FB1 carboxylesterase in detoxification ...
Lixiang Jiang +6 more
doaj +2 more sources
Enhancement of Cytosolic Carboxylesterase by Phenobarbital in the Rat [PDF]
, 1978 Previously suggested identity of soluble hepatic carboxylesterase and cytosolic aldehyde dehydrogenase was studied in the liver of the rr and RR rat substrains after phenobarbital administration. Results showed over 30% increase of carboxylesterase activity in all animals treated with phenobarbital.
Nousiainen, U. +2 more
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Carboxylesterases (EC 3.1.1). The source of variations in substrate specificity and properties of pig liver carboxylesterase [PDF]
Biochemical and Biophysical Research Communications, 1975 During the final stage of purification of pig liver carboxylesterase on CM-Sephadex, several enzyme activities are present in addition to the pig liver carboxylesterase reported from this laboratory (Horgan et al., 1969a). Variation in substrate specificity and specific activity of the material isolated from CM-Sephadex has been analysed with four ...
Hamilton S.E. +3 more
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Human Carboxylesterase 2 in Cocaine Metabolism [PDF]
, 2021 Increased hydrolysis of cocaine to non-toxic compounds is a promising way to prevent cocaine-induced toxicity. However, the short half-life of cocaine in the blood and the rapid conversion in the body to the hydrolysis-resistant metabolite ...
Alexandra T.P., Carvalho +2 more
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Carboxylesterase inhibitors [PDF]
Expert Opinion on Therapeutic Patents, 2011 Carboxylesterases play major roles in the hydrolysis of numerous therapeutically active compounds. This is, in part, due to the prevalence of the ester moiety in these small molecules. However, the impact these enzymes may play on drug stability and pharmacokinetics is rarely considered prior to molecule development.
M Jason, Hatfield, Philip M, Potter
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Rational Engineering of a Carboxylesterase for the Synthesis of Polyesters for Biomedical Applications [PDF]
, 2021 Reengineered variants of a hyperthermophilic carboxylesterase with improved product yield in the synthesis of poly(ε-caprolactone) and triblock poly(ε-caprolactone)-co-poly(ethylene glycol)Methods: Quantum Mechanics/Molecular Mechanics Molecular ...
Derek J., Quinn +8 more
core +1 more source
Environmental role of aromatic carboxylesterases [PDF]
Environmental Microbiology, 2021 Summary The carboxylesterases (EC 3.1.1.x) are widely distributed and form an important yet diverse group of hydrolases catalysing the ester bond cleavage in a variety of substrates. Besides acting on plant cell wall components like cutin, tannin and feruloyl esters, they are often the first line of defence to metabolize drugs ...
Venkatesh M. Ghodke, Narayan S. Punekar
openaire +2 more sources
Carboxylesterase-2-Selective Two-Photon Ratiometric Probe Reveals Decreased Carboxylesterase‑2 Activity in Breast Cancer Cells [PDF]
, 2018 Human carboxylesterase-2 (CE2) is a carboxylesterase that catalyzes the hydrolysis of endogenous and exogenous substrates. Abnormal CE2 levels are associated with various cancers, and CE2 is a key mediator of anticancer prodrugs, including irinotecan ...
Sang Jun Park (484359) +5 more
core +3 more sources