Results 31 to 40 of about 18,753 (228)
Characterization, sub-cellular localization and expression profiling of the isoprenylcysteine methylesterase gene family in Arabidopsis thaliana [PDF]
, 2010 Background: Isoprenylcysteine methylesterases (ICME) demethylate prenylated protein in eukaryotic cell. Until now, knowledge about their molecular information, localization and expression pattern is largely unavailable in plant species.
Wang, H.Z. +7 more
core +1 more source
Journal of Lipid Research, 2012 Z-Guggulsterone is a major ingredient in the Indian traditional hypolipidemic remedy guggul. A study in mice has established that its hypolipidemic effect involves the farnesoid X receptor (FXR), presumably by acting as an antagonist of this receptor. It
Dongfang Yang +7 more
doaj +1 more source
Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin
Frontiers in Pharmacology, 2019 Paeoniflorin, the main component of Xiaoyao Wan, presents low oral bioavailability and unclear antidepressant mechanism. To elucidate the potential reasons for the low bioavailability of paeoniflorin and explore its antidepressant mechanism from the ...
Jin-Bo Yu +12 more
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Frontiers in Bioengineering and Biotechnology, 2020 The well-studied quorum sensing (QS) mechanism has established a complex knowledge system of how microorganisms behave collectively in natural ecosystems, which contributes to bridging the gap between the ecological functions of microbial communities and
Ying Xiao +11 more
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Carboxylesterases: General detoxifying enzymes [PDF]
Chemico-Biological Interactions, 2016 Carboxylesterases (CE) are members of the esterase family of enzymes, and as their name suggests, they are responsible for the hydrolysis of carboxylesters into the corresponding alcohol and carboxylic acid. To date, no endogenous CE substrates have been identified and as such, these proteins are thought to act as a mechanism to detoxify ester ...
M Jason, Hatfield +7 more
openaire +2 more sources
Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B
Pathogens, 2021 Bioinformatics analysis of the complete transcriptome of Fasciola hepatica, identified a total of ten putative carboxylesterase transcripts, including a 3146 bp mRNA transcript coding a 2205 bp open reading frame that translates into a protein of 735 ...
Yaretzi J. Pedroza-Gómez +7 more
doaj +1 more source
Toxins, 2016 In addition to deoxynivalenol (DON), acetylated derivatives, i.e., 3-acetyl and 15-acetyldexynivalenol (or 3/15ADON), are present in cereals leading to exposure to these mycotoxins.
El Hassan Ajandouz +7 more
doaj +1 more source
Dimethyl Fumarate vs. Monomethyl Fumarate: Unresolved Pharmacologic Issues
PharmaceuticsDimethyl fumarate (DMF) has established a significant position among therapies for multiple sclerosis and psoriasis and is now being investigated for repurposing to many other non-malignant diseases.
Jana Kopincova, Iveta Bernatova
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Frontiers in Physiology, 2022 The wood-boring beetles, including the majority of Cerambycidae, have developed the ability to metabolize a variety of toxic compounds derived from host plants and the surrounding environment.
An-Jin Yang +8 more
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Current Issues in Molecular BiologyCastration-resistant prostate cancer (CRPC) remains difficult to treat with conventional chemotherapy. We evaluated a stem cell-based enzyme-prodrug strategy using hTERT-immortalized adipose-derived stem cells engineered to express rabbit ...
Jae Heon Kim +4 more
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