Results 21 to 30 of about 18,753 (228)
Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media
Microorganisms, 2022 The thermoalkalophilic membrane-associated esterase E34Tt from Thermus thermophilus HB27 was cloned and expressed in Kluyveromyces lactis (KLEST-3S esterase). The recombinant enzyme was tested as a biocatalyst in aqueous and organic media. It displayed a
Roberto González-González +8 more
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Frontiers in Pharmacology, 2020 Vicagrel, a novel acetate derivative of clopidogrel, exhibits a favorable safety profile and excellent antiplatelet activity. Studies aim at identifying genetic and non-genetic factors affecting vicagrel metabolic enzymes Cytochrome P450 2C19 (CYP2C19 ...
Shuaibing Liu +3 more
doaj +1 more source
, 2018 Human carboxylesterase-2 (CE2) is a carboxylesterase that catalyzes the hydrolysis of endogenous and exogenous substrates. Abnormal CE2 levels are associated with various cancers, and CE2 is a key mediator of anticancer prodrugs, including irinotecan ...
Sang Jun Park (484359) +5 more
core +2 more sources
Evolutionary Applications, 2021 By altering gene expression and creating paralogs, genomic amplifications represent a key component of short‐term adaptive processes. In insects, the use of insecticides can select gene amplifications causing an increased expression of detoxification ...
Julien Cattel +13 more
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Pharmaceutics, 2019 Catalposide, an active component of Veronica species such as Catalpa ovata and Pseudolysimachion lingifolium, exhibits anti-inflammatory, antinociceptic, anti-oxidant, hepatoprotective, and cytostatic activities.
Deok-Kyu Hwang +8 more
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Crystals, 2022 Ester prodrugs can develop novel antibiotics and have potential therapeutic applications against multiple drug-resistant bacteria. The antimicrobial activity of these prodrugs is activated after being cleaved by the esterases produced by the pathogen ...
Jisub Hwang +8 more
doaj +1 more source
Trypanosoma cruzi: Carboxylesterase activity in intact epimastigotes [PDF]
, 1983 1. 1. Carboxylesterase activity corresponding to types A and B has been demonstrated in intact T. cruzi epimastigotes as shown by the hydrolysis of several esters of p-nitrophenol and the effect of suitable inhibitors. 2. 2.
Repetto Scaramelli, Yolanda +2 more
core +1 more source
Microorganisms, 2021 The present study aimed to investigate effects of dual-purpose inoculants (antifungal and carboxylesterase activities) not only on corn silage quality, but also its shelf life against mold contamination at feed-out phase.
Dimas Hand Vidya Paradhipta +8 more
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Toxicology Letters, 2021 Carboxylesterases (CES) are an important class of enzymes involved in the hydrolysis of a range of chemicals and show large inter-individual variability in vitro. An extensive literature search was performed to identify in vivo probe substrates for CES1 and CES2 together with their protein content and enzymatic activity. Human pharmacokinetic (PK) data
E. Di Consiglio +7 more
openaire +4 more sources
Toxins, 2022 Gossypol is a polyphenolic toxic secondary metabolite derived from cotton. Free gossypol in cotton meal is remarkably harmful to animals. Furthermore, microbial degradation of gossypol produces metabolites that reduce feed quality.
Li Zhang +6 more
doaj +1 more source