Results 101 to 110 of about 47,563 (240)

Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products. [PDF]

, 2011
The use of compendial pH 6.8 phosphate buffer to assess dissolution of enteric coated products gives rise to poor in vitro-in vivo correlations because of the inadequacy of the buffer to resemble small intestinal fluids.
Abdul W. Basit, Agyilirah, Banwell, Bianchini, Bogentoft, Boni, Bruce, Chan, Cole, Dangel, Davis, Dressman, Ebel, Eckersley, Evans, Fadda, Fadda, Fadda, Fallingborg, Fang Liu, Garcia-Arieta, Hamid A. Merchant, Hardy, Harianawala, Ibekwe, Kararli, Lehmann, Lindahl, Liu, Maram Alkademi, McConnell, McNamara, Narasimhan, Nesbitt, Nguyen, Ozturk, Phillips, Rucha P. Kulkarni, Schiller, Shek, Sheng, Spitael, Spitael, Vanderhoff, Wilding   +44 more
core   +1 more source

Unlocking the Hepatoprotective Potential of Cyperus rotundus Through Edible Vinegar Processing: A Study on Functional Ingredient Enhancement

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Cyperus rotundus L. (CR) and vinegar‐processed CR (VCR) were compared in mouse models of thioacetamide (TAA)‐induced acute and chronic liver injury. VCR exhibited better hepatoprotective effects than raw CR. Composition analysis revealed 35 components in VCR, among which α‐cyperone was present at higher levels than in raw CR.
Gao Jia‐He, Lin Li‐Ting, Liu Yue‐Han, Wang Fu‐Chao, Liu Jun‐Tong, Gao Tian‐Hui   +5 more
wiley   +1 more source

Dizajniranje, sinteza, kinetika hidrolize i farmakodinamski profili konjugata aceklofenaka s histidinom i alaninom [PDF]

, 2010
The gastrointestinal toxicity associated with aceclofenac can be reduced by condensing its carboxylic acid group with methyl esters of amino acids like histidine and alanine to give amide linkage by the Schotten-Baumann method.
A. Kay, A. Mishra, A. Mishra, A. Rasheed, A. Rasheed, Arun Rasheed, C. Kumar, C. Winter, D. Bhosle, J. Idle, M. Yagmurca, N. Gairola, N. Nielsenw, R. Goyal, S. Kulkarni, S. Roy   +15 more
core   +2 more sources

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Triamcinolone Acetonide Oromucoadhesive Paste for Treatment of Aphthous Stomatitis

Advanced Pharmaceutical Bulletin, 2015
Purpose: The aim of this study was to prepare the optimized oral paste formulation of Triamcinolone acetonide intended to be used in aphtous stomatitis. Methods: Plastibases were prepared using mineral oil and polyethylene (95:5).
Hamed Hamishehkar, Ali Nokhodchi, Saeed Ghanbarzadeh, Maryam Kouhsoltani   +3 more
doaj   +1 more source

Hydraulic conductivity and swelling pressure of GCLs using polymer treated clays to high concentration CaCl(2) solutions [PDF]

, 2015
A Geosynthetic Clay Liner (GCL) is a frequently used h ydraulic barrier system designed to impede the flow of contaminated leachate into the environment.
Bezuijen, Adam, D, Verastegui Flores, Di Emidio, Gemmina, Janssen, J   +3 more
core  

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson, Akeel, Al-Assaf, Al-Assaf, B.J. Parsons, Balazs, C. Houee-Levin, Camenisch, Chawla, D.J. Heyes, Dogliotti, Eriksen, Hardingham, Hawkins, Hayon, Hayon, Heckel, Heinecke, Huie, Ivanov, J.-L. Marignier, Jiang, Johnson, Kennett, Kennett, Kettle, Laurent, Laurent, McElroy, McElroy, McGowan, Milner, Misra, Parsons, Parsons, Pattison, Pattison, Pattison, Pe Myint, Poskrebyshev, Redpath, Rees, Rees, Rees, Rees, Rees, Rees, S. Sibanda, Schwarz, Stern, Swallow, Tang, Thomas, Thomas, Thorne, Toole, Toole, Toole, Turley, van Golen, von Sonntag, Weeks, Weiss, Weiss, Wine, Wolfenden, Woods, Zao   +67 more
core   +1 more source

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole‐induced pain

British Journal of Pharmacology, Volume 183, Issue 9, Page 2009-2027, May 2026.
Abstract Background and Purpose Anastrozole, an aromatase inhibitor, is used to treat postmenopausal women with hormone receptor‐positive breast cancer, but also induces musculoskeletal pain and can lead to therapeutic regimen suspension. Aromatase inhibitors promote the release of pro‐inflammatory substances from sensitised nerve fibres, which might ...
Maria Fernanda Pessano Fialho, Raquel Tonello, Evelyne Silva Brum, Gabriela Becker, Nigel W. Bunnett, Sara Marchesan Oliveira   +5 more
wiley   +1 more source

Feasible Regions of Nozzle Temperature, Extrusion Pressure, and Printing Speed in Extrusion-Based Printing Using a Sodium Alginate–Carboxymethylcellulose–Collagen I Bioink

Biomimetics
This study determines the feasible regions of nozzle temperature, extrusion pressure, and printing speed in extrusion-based printing using an acellular sodium alginate–carboxymethylcellulose–collagen I bioink.
Evgenia Dimitriou, Nathan Wood, Hongmin Qin, Zhijian Pei   +3 more
doaj   +1 more source

Properties of Composite Oleogels Based on Soybean Isolate Protein Reinforced with Sodium Carboxymethylcellulose [PDF]

Shipin Kexue
The indirect preparation of oleogels by the aerogel template method has received widespread attention due to its advantages such as simple operation and excellent performance.
CUI Mengqi, SHAN Guancheng, SUN Ruohan, TIAN Bo, SUI Xiaonan
doaj   +1 more source