Results 51 to 60 of about 3,110 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MENINGKATKAN KEKUATAN FATIQUE BAJA AISI 1020 MELALUI PROSES PACK CARBURIZING MENGGUNAKAN ARANG TEMPURUNG KELAPA

, 2021
The aim of the study was to determine the effect of heat treatment in the form of pack carburizing on the microhardness of the surface, the distribution of surface hardness, changes in the microstructure and fracture structure of the specimen before and ...
Joni
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Final Scientific Report - "Novel Steels for High Temperature Carburizing"

, 2012
This program was undertaken to develop a microalloy-modified grade of standard carburizing steel that can successfully exploit the high temperature carburizing capabilities of current commercial low pressure (i.e. 'vacuum') carburizing systems.
McKimpson, Marvin G., Liu, Tianjun, Maniruzzaman, Md   +2 more
core   +1 more source

Carburizing of Steel [PDF]

International Journal of Materials Science and Applications, 2015
Paraffin wax (sulfur and phosphorous free)used as carburizer material for low carbon steels(Steel20, Steel3, and Steel 20x) instead of kerosene. Results show 1) Carburized layer by wax is more depth than in case of kerosene for all the three types of steel, e.g.
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Optimum factors between carburizing Temperature and Time in Hardening Big Knife by Pack Carburizing Process Using Periwinkle Shells as an Energizer

, 2022
งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาปัจจัยที่เหมาะสมของอุณหภูมิและเวลาการอบเพิ่มคาร์บอนที่มีผลต่อสมบัติเชิงกลของมีดโต้ที่ชุบแข็งด้วยกระบวนการแพ็กคาร์เบอไรซิงโดยใช้เปลือกหอยขมเป็นสารเร่งปฏิกิริยา สมบัติเชิงกลของมีดโต้ประกอบด้วยค่าความแข็งและความต ...
Homjabok, Wanna; Department Material Engineering, Faculty of Engineering and Architecture, Rajamangala University of Technology Isan, Nakhonratchasima, Thammachot, Narongsak; Department Material Engineering, Faculty of Engineering and Architecture, Rajamangala University of Technology Isan, Nakhonratchasima, Noyming, Sombut; Department Material Engineering, Faculty of Engineering and Architecture, Rajamangala University of Technology Isan, Nakhonratchasima, Mayai, Amornsak; Department Industrial Engineering, Faculty of Engineering and Architecture, Rajamangala University of Technology Isan   +3 more
core   +1 more source

Effects of WC Particle Size and Co Content on the Graded Structure in Functionally Gradient WC-Co Composites

MATEC Web of Conferences, 2016
Functionally gradient WC-Co composites having a Co depleted surface zone and not comprising the h phase can be manufactured via carburizing process.
Yuan Yigao, Fu Lanping, Li Jianpeng
doaj   +1 more source

MICROANALYSE DES JOINTS CARBURE-CARBURE DANS LES COMPOSITES CARBURE DE TUNGSTÈNE-COBALT [PDF]

Le Journal de Physique Colloques, 1984
La concentration en cobalt aux joints de grains carbure-carbure des composites WC-Co a été déterminée par microanalyse X à sélection d'énergie en microscopie électronique à balayage en transmission. Il a été montré que seuls, les joints généraux se caractérisaient par une forte augmentation de la concentration en cobalt. Il est possible d'en déduire la
Laval, J., Vicens, J., Nouet, G.
openaire   +1 more source