Results 151 to 160 of about 84,117 (291)

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, Volume 20, Issue 5, Page 1220-1236, May 2026.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Predictive value of primary gross tumor volume measured by MRI in response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Journal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Background Neoadjuvant chemoradiotherapy (nCRT) is a standard treatment for locally advanced rectal cancer (LARC), yet individual tumor regression response varies considerably. Purpose This study aimed to identify clinical factors linked to tumor regression grade (TRG) after nCRT in LARC and to evaluate MRI‐measured primary gross tumor volume (
Junbiao Li, Yuduo Wu, Shaoping Ye, Cuiying Fan, Yanping Lin, Dianhua Yang, Xiaoyi Xia, Yajing Kang, Dehao Liu, Junxin Wu   +9 more
wiley   +1 more source

Multiple Oral and Eyelid Nodules in a Pediatric Patient

Oral Diseases, EarlyView.
Caique Mariano Pedroso, Paulo Victor Mendes Penafort, Patrícia Vitor de Souza, Fernanda M. Pascon, Regina Maria Punppin‐Rontani, Beatriz Frolini Paulo Cherve, Rachel Marinho Robim, Regina Maria Holanda de Mendonça, Marcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos‐Silva   +10 more
wiley   +1 more source

High Stability of Diketopyrrolopyrrole Polymer Transistors Under Aqueous Condition Toward Biosensing Platform

Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
We are reporting the first‐time investigation of DPP‐based Organic Field‐Effect Transistor (OFET) devices with high‐stability of signal response in both of ambient and aqueous conditions with PBS solution. ABSTRACT Diketopyrrolopyrrole (DPP)–based conjugated polymers show strong promise for electronic applications, including bioelectronic gas sensors ...
Chattarika Khamhanglit, Yudai Hemmi, Ami Ichikawa, YuanTong Gu, Kuniaki Nagamine, Hiroyuki Matsui, Prashant Sonar   +6 more
wiley   +1 more source

Real‐Time Digital Micromotor Tracking‐Enabled Ultrasensitive Immunoassay

Advanced Science, Volume 13, Issue 25, 4 May 2026.
An AI‐facilitated real‐time digital micromotor tracking‐enabled immunoassay is developed, which leverages a self‐developed multi‐microparticle tracking system to monitor micromotor motion trajectories in a real‐time manner for digital protein analysis.
Jingjing Shi, Zuhua Yu, Hui Tian, Wenjiao Fan, Yuanyuan Sun, Wei Ren, Chenghui Liu   +6 more
wiley   +1 more source

To Evaluate Whether Pretreatment CA19‐9 and DUPAN‐2 Levels Can Serve as Predictive Markers to Guide the Choice Between NAT and Upfront Surgery in Pancreatic Cancer

Annals of Gastroenterological Surgery, Volume 10, Issue 3, Page 835-842, May 2026.
NAT‐GS was significantly more effective only in patients with one tumor marker above the reference range, comparing those who achieved 12‐month MRFS with those who did not. ABSTRACT Aim Pancreatic cancer (PC) remains one of the most lethal malignancies, with early recurrence severely affecting prognosis even after curative resection.
Hiromichi Kawaida, Wataru Izumo, Ryo Saito, Hidetake Amemiya, Suguru Maruyama, Katsutoshi Shoda, Kensuke Shiraishi, Shinji Furuya, Yoshihiko Kawaguchi, Daisuke Ichikawa   +9 more
wiley   +1 more source

Carcinoembryonic Antigen: Beyond a Gastrointestinal Tumour Marker. [PDF]

Cureus
Tun AA, Tan CY, Sumitro K, Salim F, Lim KC, Yong A, Heng Chong V.   +6 more
europepmc   +1 more source

Carcinoembryonic antigen radioimmunodetection

Gastroenterology, 1983
P W, Dykes, A R, Bradwell
openaire   +2 more sources

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, Volume 10, Issue 3, Page 722-738, May 2026.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source