Results 171 to 180 of about 1,109,000 (367)

Blurring the Lines: Co‐Occurrence of MSH6 Variant and MLH1 Constitutional Epimutation in a Young Colorectal Cancer Patient

open access: yesClinical Genetics, EarlyView.
We report a unique case of early‐onset colorectal cancer with both a germline MSH6 variant and constitutional mosaic MLH1 epimutation, revealing a possible digenic mechanism underlying Lynch syndrome. This case highlights the diagnostic complexity of mismatch repair deficiency and the value of integrative tumor–germline molecular profiling.
Aasem Abu Shtaya   +7 more
wiley   +1 more source

The Carcinoembryonic Antigen Level Among Tobacco Workers

open access: gold, 2009
Yıldız Pekşen   +3 more
openalex   +2 more sources

Sa1443 CYST FLUID CARCINOEMBRYONIC ANTIGEN DIFFERENCE AMONG MUCINOUS CYSTIC NEOPLASMS AND INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS [PDF]

open access: bronze, 2020
İbrahim Hakkı Köker   +4 more
openalex   +1 more source

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina   +8 more
wiley   +1 more source

Carcinoembryonic Antigen and the Liver

open access: yesGastroenterology, 1977
M S, Loewenstein, N, Zamcheck
openaire   +2 more sources

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

open access: yesThe FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson   +5 more
wiley   +1 more source

Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a dismal prognosis, largely because of late‐stage diagnosis and therapeutic resistance. PDAC incidence has been rising, with modifiable and non‐modifiable risk factors contributing to disease development.
Alessandro Mannucci, Ajay Goel
wiley   +1 more source

Rectal metastasis from lung cancer diagnosed by endoscopic ultrasound‐guided fine needle biopsy: A case report

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract A 73‐year‐old man visited our hospital due to hyperintestinal peristalsis and diarrhea. He had been undergoing regular annual checkups for dust lung disease. Contrast‐enhanced computed tomography scan showed edematous thickening of the rectal wall with contrast effect.
Shinji Mukawa   +8 more
wiley   +1 more source

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