A novel electrochemical immunosensor based on biomaterials for detecting carcinoembryonic antigen biomarker in serum samples. [PDF]
Sobhanparast S +6 more
europepmc +1 more source
CEACAM6: A potential prognostic biomarker and therapeutic target in cholangiocarcinoma
Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Jia‐Qi Guo +3 more
wiley +1 more source
ABSTRACT Introduction Research on immune checkpoint molecules is increasing, reflecting their critical role in cancer pathogenesis. While PD‐1, PD‐L1, and CTLA‐4 have been widely studied in head and neck cancers, outcomes remain unsatisfactory, highlighting the need for novel prognostic markers and therapeutic targets.
Fırat Tevetoğlu +2 more
wiley +1 more source
Identifying the Primary Tumor Site and Distinguishing False-positives in Patients With Elevated Serum Carcinoembryonic Antigen. [PDF]
Satoh H +4 more
europepmc +1 more source
Gut microbiome plays a crucial role in colorectal cancer development. The advanced sequencing techniques have the potential to complement current non‐invasive methods for early diagnosis and prevention of colorectal cancer. This includes conducting studies with robust statistical power and consistent, replicable methodologies, taking into consideration
Parvin Askari +10 more
wiley +1 more source
Ultra-low limit of detection of a carcinoembryonic antigen fiber sensor based on microfiber. [PDF]
Wan J +8 more
europepmc +1 more source
Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge +9 more
wiley +1 more source
Septin-9 gene methylation and carcinoembryonic antigen as key biomarkers in colorectal cancer: A retrospective study on prognosis and recurrence. [PDF]
Liu J.
europepmc +1 more source
Gas Biopsy of Pleural Effusion to Diagnose Lung Cancer by Mass Spectrometry
HS‐SPME–GC–MS profiling of pleural effusion revealed distinct volatile metabolic features between lung cancer‐associated malignant pleural effusion and benign pleural effusion. Cross‐matrix integration with paired lung cancer tissues identified hexanal as the only shared differential VOC.
Wenting Liu +10 more
wiley +1 more source
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao +14 more
wiley +1 more source

