Results 221 to 230 of about 84,117 (291)

Cholangiolocellular Component Predicts a Biologically Distinct Subgroup of Mass‐Forming Intrahepatic Cholangiocarcinoma

open access: yesCancer Science, Volume 117, Issue 5, Page 1510-1523, May 2026.
We identified two distinct molecular subgroups of mass‐forming intrahepatic cholangiocarcinoma (MF‐iCCA) based on the presence of a histological cholangiolocellular carcinoma (CLC) component. The CLC‐related molecular subgroup showed better prognosis and highly angiogenic features, as confirmed by both genetic analysis and morphological observation ...
Naoto Kubota   +9 more
wiley   +1 more source

Pulmonary Langerhans Cell Histiocytosis Presenting as Multiple Obstructing Bronchial Lesions and Pulmonary Masses

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
We describe a case of PLCH presenting as multiple obstructing bronchial lesions and pulmonary masses in a 36‐year‐old man. To our knowledge, this is the first report of PLCH presenting as bilateral hilar masses and airway obstructive lesions. ABSTRACT Pulmonary Langerhans cell histiocytosis is a rare lung disease, which was previously classified as ...
Jingyuan Fan   +3 more
wiley   +1 more source

The Multifaceted Role of Keratinocytes in Hidradenitis Suppurativa Pathogenesis

open access: yesExperimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder of the pilosebaceous unit, with multiple factors contributing to its onset, activity and progression. Alongside a predisposing genetic background, hormonal and microbiome alterations, dysregulation of innate and adaptive immune response, as well as environmental ...
Chiara Moltrasio   +2 more
wiley   +1 more source

The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu   +7 more
wiley   +1 more source

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