Results 241 to 250 of about 84,483 (336)

Unlocking T‐Cell Plasticity in the Tumor Microenvironment: Implications for Cancer Progression and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
The tumor microenvironment (TME) shapes T‐cell plasticity, influencing cancer progression and therapeutic outcomes. Here, we summarize the phenotypic transitions and spatial distribution of T cells within the TME, highlighting their dual roles in therapeutic efficacy and resistance.
Xiao‐Hong Ding   +4 more
wiley   +1 more source

Olanzapine enabled rechallenge after lorlatinib‐induced psychosis: A case report

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Antipsychotic treatment for lorlatinib‐induced psychotic symptoms enables lorlatinib rechallenge and targeted therapy for lung cancer. Abstract Background Lorlatinib is a third‐generation tyrosine kinase inhibitor for anaplastic lymphoma kinase (ALK)‐positive non‐small cell lung cancer (NSCLC).
Akiyoshi Yokode   +5 more
wiley   +1 more source

Diagnostic Dilemma in a Case of Anti‐PL‐7 Antibody‐Positive Interstitial Lung Disease: When Autoimmune Alveolar Proteinosis Masquerades as Anti‐Synthetase Syndrome

open access: yesRespirology Case Reports, Volume 13, Issue 6, June 2025.
Pulmonary alveolar proteinosis (PAP) and anti‐PL‐7 antibody‐positive interstitial lung disease (ILD) share early radiographic similarities, yet their treatments differ significantly. This article reports a rare case of dual anti‐PL‐7 and anti‐GM‐CSF autoantibody positivity, initially misdiagnosed as anti‐synthetase syndrome due to interstitial ...
Beili Liu   +5 more
wiley   +1 more source

Carcinoembryonic Antigen Expression in Human Tumors: A Tissue Microarray Study on 13,725 Tumors. [PDF]

open access: yesCancers (Basel)
Jansen K   +27 more
europepmc   +1 more source

Robot‐Assisted Colectomy for Left‐Sided Colon Cancer: Comparison of da Vinci SP and Single‐Site Platforms

open access: yesThe International Journal of Medical Robotics and Computer Assisted Surgery, Volume 21, Issue 3, June 2025.
ABSTRACT Background To compare the clinicopathological and cosmetic outcomes of robotic colectomy using the da Vinci SP and Single‐Site for left‐sided colon cancer. Methods The study included 31 and 52 patients who underwent robotic colectomy using the SP and Single‐Site, respectively, between July 2011 and July 2023.
Kyeong Eui Kim   +3 more
wiley   +1 more source

The Impact of KRAS Status on Long‐Term Outcomes After Thermal Ablation and Hepatic Resection for Liver‐Only Colorectal Metastases: A New Clue for Tailoring Surgical Strategy on Tumor Biology?

open access: yesWorld Journal of Surgery, Volume 49, Issue 6, Page 1573-1582, June 2025.
KRAS mutation is a negative prognostic factor for colorectal liver metastases (CRLM). Thermal ablation (TA) is considered a valid alternative to liver resection (LR) for CRLM in selected cases. This study aims to investigate the influence of KRAS status on long‐term outcomes of TA during LR.
Fabio Giannone   +10 more
wiley   +1 more source

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