Results 61 to 70 of about 84,483 (336)

Cloning of a Carcinoembryonic Antigen Gene Family Member Expressed in Leukocytes of Chronic Myeloid Leukemia Patients and Bone Marrow [PDF]

, 1990
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin superfamily and can be subdivided into the CEA and pregnancy-specific glycoprotein subgroups.
Berling, Barbara, Brombacher, Frank, Buchegger, Franz, Grunert, Fritz, Kleist, Sabine von, Kolbinger, Frank, Thompson, John A., Zimmermann, Wolfgang   +7 more
core   +1 more source

Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer. [PDF]

, 2017
BackgroundT cells engineered to express chimeric antigen receptors (CARs) have established efficacy in the treatment of B-cell malignancies, but their relevance in solid tumors remains undefined.
A Molinolo, A Stasi Di, A Thor, B Fisher, BA Irving, BL Levine, C Romeo, CC Kloss, CY Wu, D Moritz, DL Porter, DW Lee, F Guadagni, HM Finney, I Blanco, I Stancovski, J Scholler, JD Wolchok, JL Murray, JN Kochenderfer, JW Greiner, KD Griffith, L Naldini, M Hegde, M Kalos, ME Dudley, MH Finer, MH Kershaw, ML Davila, MR Lander, N Gonzales, NP Restifo, P Hwu, RA Morgan, RE Walker, RF Meredith, RP McGuinness, RT Mitsuyasu, S Guedan, SD Patel, SG Deeks, SL Maude, SV Kashmiri   +42 more
core   +1 more source

Carcinoembryonic antigen in sputum.

The Tohoku Journal of Experimental Medicine, 1982
Carcinoembryonic antigen (CEA) levels in sputum from patients with lung cancers (15), other malignancies (7) and non-malignant pulmonary diseases (30) were measured by enzyme immunoassay. The mean value +/- S.E. (ng/ml) of CEA levels in sputum was 3,682 +/- 1,648, 630 +/- 473 and 444 +/- 102, respectively.
Yasuo Tanno, Tamotsu Takishima, Kiyo Nishioka   +2 more
openaire   +4 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Evaluation of the Sensitivity and Specificity of Immunohistochemical Markers in the Differential Diagnosis of Effusion Cytology

Oman Medical Journal, 2013
Objective: To evaluate the sensitivity and specificity of Calretinin and Carcinoembryonic antigen as immunocytochemical markers in distinguishing mesothelial cells from metastatic adenocarcinoma cells in effusion cytology.Methods: This study included 50 ...
Zahraa Mohammed Yahya, Hussam Hasson Ali, Haider Ghazi Hussein   +2 more
doaj   +1 more source

Serum carcinoembryonic antigen elevation in benign lung diseases

Scientific Reports, 2021
Carcinoembryonic antigen (CEA) is not only used to aid the diagnosis of lung cancer, but also help monitor recurrence and determine the prognosis of lung cancer as well as evaluate the therapeutic efficacy for lung cancer.
Yi Yang, Mingfang Xu, Huan Huang, Xiaolin Jiang, Kan Gong, Yun Liu, Xunjie Kuang, Xueqin Yang   +7 more
doaj   +1 more source

Mice Transgenic for the Human Carcinoembryonic Antigen Gene Maintain Its Spatiotemporal Expression Pattern [PDF]

, 1994
The tumor marker carcinoembryonic antigen (CEA) is predominantly expressed in epithelial cells along the gastrointestinal tract and in a variety of adenocarcinomas.
Eades-Perner, Anne-Marie, Hirth, Antje, Kleist, Sabine von, Neumaier, Michael, Putten, Herman van der, Thompson, John A., Zimmermann, Wolfgang   +6 more
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

A study of human carcinoembryonic antigen as a biomarker for assessing the severity of stroke

APIK Journal of Internal Medicine, 2021
Background and Objectives: Human carcinoembryonic antigen (CEA) is widely used as a tumor marker. Striking similarities have been reported between process of tumor genesis and atherosclerotic diseases.
Vishwanath Krishnamurthy, Sonia Srinivas, Sujatha K Jayaram, Arun Narayan, Megha Reddy, Arun Patted   +5 more
doaj   +1 more source

The Carcinoembryonic Antigen Gene Family [PDF]

, 1988
The molecular cloning of carcinoembryonic antigen (CEA) and several cross-reacting antigens reveals a basic domain structure for the whole family, which shows structural similarities to the immunoglobulin superfamily.
Thompson, John A., Zimmermann, Wolfgang
core