Results 41 to 50 of about 2,431 (191)
Hepatitis B Viral Mutants and Their Relevance to the Canadian Health Care System
Over the past 10 years, an increasing number of mutations in the hepatitis B virus genome have been described. While the majority of these mutations appear to be ‘silent’ or not clinically relevant, some have been described in association with increased severity of disease (core and basic core promoter mutations), evasion of immunological surveillance (
Gerald Y Minuk
wiley +1 more source
Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer
Hypoxia is an inherent condition of tumors and contributes to cancer development and progression. Hypoxia-inducible factors (HIFs) are the major transcription factors involved in response to low O2 levels, orchestrating the expression of hundreds of ...
Diego Camuzi +5 more
doaj +1 more source
The reasons for the worldwide decline in stomach cancer incidence and mortality rates are not fully understood, but dietary changes are clearly implicated. While the possible mechanisms of gastric carcinogenesis and the impact of Helicobacter pylori eradication remain open to debate, at least two practical recommendations – to increase fruit and ...
Carlo La Vecchia, Silvia Franceschi
wiley +1 more source
Carcinogênese Química Experimental em Glândulas Salivares - Revisão da Literatura
Introdução: As neoplasias malignas mais encontradas em carcinogênese experimental de glândulas salivares animais são os carcinomas e os sarcomas, associados ou não. O diagnóstico de carcinossarcomas somente foi aludido em estudos recentes.
Pietro Mainenti +1 more
doaj +1 more source
Abstract To meet the screening goal of WHO's 90‐70‐90 strategy aimed at eliminating cervical cancer (CC) by 2030, clinical validation of human papillomavirus (HPV) assays is essential to provide accurate and valid results through fulfilling three criteria of the international validation guidelines (IVGs).
Pui Yan Jenny Chung +7 more
wiley +1 more source
Dysplasia in Inflammatory Bowel Diseases: Definition and Clinical Impact
Dysplasia is a morphological term that ethymologically means ‘malformation’. For the definition of inflammatory bowel disease‐related dysplasia, the nature and origin of the malformation are stressed and the lesion is defined as an epithelial malformation that is unequivocally neoplastic but noninvasive.
Karel Geboes, Paul Rutgeerts
wiley +1 more source
Efeito de promotores tumorais em pele de gerbil, Meriones unguiculatus
Supondo que a resistência relativa da pele de gerbil adulto à carcinogênese química estaria relacionada a um fenômeno de adaptação ao processo de promoção tumoral, foi caracterizado o efeito de óleo de cróton (OC) e peróxido de benzoíla (PB) sobre a ...
Maria Angélica Guzmán-Silva
doaj +1 more source
An overview of multiomics: a powerful tool applied in cancer molecular subtyping for cancer therapy
The review provides an overview of the advanced technologies and recent progress in multiomics applied in cancer molecular subtyping, and detailedly explains the application of multiomics in identifying cancer driver genes and metastasis‐related genes, exploring tumor microenvironment, and selecting liquid biopsy biomarkers and potential therapeutic ...
Yazhu Zou, Zitong Zhao, Yongmei Song
wiley +1 more source
The pathology of gastritis associated with Helicobacter pylori infection is summarized. The literature is reviewed regarding the role of H pylori in the pathogenesis of gastric carcinoma and mucosa‐associated lymphoid tissue (MALT) lymphoma. The potential mechanisms of gastric carcinogenesis include transformation of the gastric mucosa by metabolic ...
M Guindi
wiley +1 more source
Carcinogênese vulvar relacionada ao líquen escleroso: revisão de literatura
O câncer vulvar é uma neoplasia ginecológica de baixa incidência, acometendo mulheres com uma média de idade ao diagnóstico de 68 anos. O tipo histológico mais comum é o carcinoma de células escamosas, que corresponde a 80% dos cânceres vulvares.
Moura, Amanda de Freitas Ferreira de
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