Results 31 to 40 of about 461 (113)

MYB Activates the Hedgehog Signaling Pathway to Repress Natural Killer Cytotoxicity in Cervical Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 41, Issue 12, December 2025.
ABSTRACT Natural killer (NK) cells present in the tumor microenvironment serve as a critical line of defense against various malignancies, including cervical cancer. While MYB is known to drive malignancy progression, its influence on NK cell activity remains poorly understood.
Yu Wang, Chen Li
wiley   +1 more source

Hepatitis B Viral Mutants and Their Relevance to the Canadian Health Care System

open access: yesCanadian Journal of Gastroenterology and Hepatology, Volume 16, Issue 1, Page 45-54, 2002., 2002
Over the past 10 years, an increasing number of mutations in the hepatitis B virus genome have been described. While the majority of these mutations appear to be ‘silent’ or not clinically relevant, some have been described in association with increased severity of disease (core and basic core promoter mutations), evasion of immunological surveillance (
Gerald Y Minuk
wiley   +1 more source

Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer

open access: yesCells, 2019
Hypoxia is an inherent condition of tumors and contributes to cancer development and progression. Hypoxia-inducible factors (HIFs) are the major transcription factors involved in response to low O2 levels, orchestrating the expression of hundreds of ...
Diego Camuzi   +5 more
doaj   +1 more source

Nutrition and Gastric Cancer

open access: yesCanadian Journal of Gastroenterology and Hepatology, Volume 14, Issue D, Page 51D-54D, 2000., 2000
The reasons for the worldwide decline in stomach cancer incidence and mortality rates are not fully understood, but dietary changes are clearly implicated. While the possible mechanisms of gastric carcinogenesis and the impact of Helicobacter pylori eradication remain open to debate, at least two practical recommendations – to increase fruit and ...
Carlo La Vecchia, Silvia Franceschi
wiley   +1 more source

Carcinogênese Química Experimental em Glândulas Salivares - Revisão da Literatura

open access: yesRevista Brasileira de Cancerologia, 2008
Introdução: As neoplasias malignas mais encontradas em carcinogênese experimental de glândulas salivares animais são os carcinomas e os sarcomas, associados ou não. O diagnóstico de carcinossarcomas somente foi aludido em estudos recentes.
Pietro Mainenti   +1 more
doaj   +1 more source

Intra‐ and interlaboratory reproducibility evaluation toward international validation status of the AmpFire assay

open access: yesJournal of Medical Virology, Volume 96, Issue 6, June 2024.
Abstract To meet the screening goal of WHO's 90‐70‐90 strategy aimed at eliminating cervical cancer (CC) by 2030, clinical validation of human papillomavirus (HPV) assays is essential to provide accurate and valid results through fulfilling three criteria of the international validation guidelines (IVGs).
Pui Yan Jenny Chung   +7 more
wiley   +1 more source

Dysplasia in Inflammatory Bowel Diseases: Definition and Clinical Impact

open access: yesCanadian Journal of Gastroenterology and Hepatology, Volume 13, Issue 8, Page 671-678, 1999., 1999
Dysplasia is a morphological term that ethymologically means ‘malformation’. For the definition of inflammatory bowel disease‐related dysplasia, the nature and origin of the malformation are stressed and the lesion is defined as an epithelial malformation that is unequivocally neoplastic but noninvasive.
Karel Geboes, Paul Rutgeerts
wiley   +1 more source

An overview of multiomics: a powerful tool applied in cancer molecular subtyping for cancer therapy

open access: yesMalignancy Spectrum, Volume 1, Issue 1, Page 15-29, March 2024.
The review provides an overview of the advanced technologies and recent progress in multiomics applied in cancer molecular subtyping, and detailedly explains the application of multiomics in identifying cancer driver genes and metastasis‐related genes, exploring tumor microenvironment, and selecting liquid biopsy biomarkers and potential therapeutic ...
Yazhu Zou, Zitong Zhao, Yongmei Song
wiley   +1 more source

Role of Helicobacter pylori in the Pathogenesis of Gastric Carcinoma and Progression of Lymphoid Nodules to Lymphoma

open access: yesCanadian Journal of Gastroenterology and Hepatology, Volume 13, Issue 3, Page 224-227, 1999., 1999
The pathology of gastritis associated with Helicobacter pylori infection is summarized. The literature is reviewed regarding the role of H pylori in the pathogenesis of gastric carcinoma and mucosa‐associated lymphoid tissue (MALT) lymphoma. The potential mechanisms of gastric carcinogenesis include transformation of the gastric mucosa by metabolic ...
M Guindi
wiley   +1 more source

Revisão Atual da Expressão da Beta-Catenina e suas Implicações no Estudo da Displasia Epitelial Bucal

open access: yesRevista Brasileira de Cancerologia, 2010
O surgimento do câncer bucal é frequentemente precedido pelo aparecimento de alguma desordem potencialmente maligna, que pode ser definida como alteração morfológica tecidual, na qual há maior probabilidade de surgimento de neoplasia maligna do que num ...
Allan Ulisses Carvalho de Melo   +5 more
doaj   +1 more source

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