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Chemical carcinogenesis [PDF]
Anais da Academia Brasileira de Ciências, 2007 The use of chemical compounds benefits society in a number of ways. Pesticides, for instance, enable foodstuffs to be produced in sufficient quantities to satisfy the needs of millions of people, a condition that has led to an increase in levels of life expectancy.Oliveira, Paula A., Colaço, Aura, Chaves, Raquel, Guedes-Pinto, Henrique, De-La-Cruz P., Luis F., Lopes, Carlos +5 morecore +8 more sourcesChemical Carcinogenesis [PDF]
Toxicological Sciences, 2010 Understanding the relationship of chemicals to carcinogenesis has progressed significantly since the initial observations of Hill and Pott in the 1700's. Distinguishing between DNA-reactive chemicals and those which increase cancer risk by increasing cell proliferation has been a major breakthrough in delineating overall mechanisms. Competing processes Samuel M, Cohen, Lora L, Arnoldopenaire +2 more sourcesAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]
, 2015 Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...H. K. Salem, Langie, A. S. Sabine, Koppen, G., Colacci, Anna Maria, Yunus Luqmani, James E. Klaunig, Guarnieri, Tiziana, R. Andrade Vieira, Jan Vondráček, Rabindra Roy, Hsu, C-W, Laconi, E., I. Koturbash, A. Ward, S. Luanpitpong, Patricia A. Thompson, Otsuki T, Lyerly, H.K., Naus, C., Vento R, Hsu, H. Y., Romano MF, Whitfield, Jonathan R, Silvana Papagerakis, Salzberg, A. C., Bisson, H. William, Kuemmerle, Nancy B., Klaunig JE, Amaya Azqueta, Sudjit Luanpitpong, Ahmed, Nuzhat, Collins, Andrew R., Vermeulen, Louis, Van Schooten FJ, Vaccari, Monica, Dent, P., Z. Chen, J. Roman, Felsher, Dean W., Whitfield, J., Hultman, Tove, Martin, F. L., Christopher, JA, Carnero A, Ghosh PM, R. Vento, Otsuki, T, Sabbisetti V, Narayanan, K. B., Ponce-Cusi, Richard, Amedei, Amedeo, Kannan Badri Narayanan, Engström, Wilhelm, Whitfield, JR, Harris, Shelley A., Leung, P. S., Vondráček, J, Di Fiore, R., Thompson, P., Ochieng, J, Matilde E. Lleonart, Koppen, G, Kleinstreuer, Nicole, Bisson, William H., Nahta R, Riccardo Di Fiore, Fernando Martinez-Leal, Juan, Forte S, Singh, Neetu, J. Ochieng, Sabbisetti, Venkata, Marignani PA, Thompson, Patricia, Curran, Colleen S, Carlin, J. Danielle, Hultman, T., Y. Luqmani, Wade, M., Kondoh, H, Rathmell WK, Ranjeet K. Sinha, Ab Hamid, H., Lee, TJ, Kim Moorwood, Ward, Andrew, Christopher, A. Joseph, Marignani, Paola A, Anna C. Salzberg, Jian, L., Gonzalez, Michael J, Lyerly, H Kim, Ghosh, Paramita M, Goodson III, William H, A. Lopez de Cerain Salsamendi, Chen Z, F. Marongiu, Salzberg AC, Decker WK, Manjili, Masoud H, Vadgama, P., Dong C, Chen T, Anna Maria Colacci, Salem, Hosni K, Olsen, Ann-Karin, G. Wagemaker, Sanderson T, E. Ratovitski, Odero-Marah, V, Gonzalez, L, Z. Hu, Raju, J., Odero Mara, Valerie, Eun-Yi Moon, Collins, A. R., L. Leyns, Krishnan, Harini, Salzberg, A.C., Ogunkua, Olugbemiga, S. Forte, Wise Sr., John Pierce, Abd Hamid, R, Narayanan, Kannan Badri, Laconi, E, Bisson, William H, J. P. Wise, Hyun, Ho Park, Soucek, L., Rojas, Emilio, Rojanasakul, Yon, Sandra Ryeom, Kondoh H, Rojanasakul Y, Harini Krishnan, Guarnieri, T., Scovassi, a Ivana, Nangami, Gladys N., Colacci, Annamaria, Koturbash, I., Karamouzis, Michalis V, Darbre, P., S. Eriksson, McCawley, Lisa J., F. Al Mulla, Lyerly HK, Ostrosky Wegman P, Goldberg GS, A. R. Collins, Ali, Abdul Manaf, Jonathan R. Whitfield, Emanuela Corsini, Nancy B. Kuemmerle, Lleonart, Matilde E, Cheng, Q. S., Langie, Sabine A.S., Lee, T., Nicole Kleinstreuer, Ab Hamid, Hasiah, Sofia Pavanello, Yedjou, C, Jian, Le, Sinha, K. Ranjeet, Yedjou C, Massfelder T, F. L. Martin, Pavanello, S, Valverde, M., Micheline Kirsch-Volders, Valérian Dormoy, H. Yasaei, Collins, A., Massfelder, T, Laird, Dale W., A. Manaf Ali, Ghosh, M. Paramita, H. Sone, Salzberg, C. Anna, Goldberg, G., Hamid, H. A., Clement Yedjou, Carlin, DJ, Ogunkua O, Christian C. Naus, Sinha, Ranjeet K., Scovassi AI, Odero-Marah, Valerie, Nangia Makker, P., Van Schooten, F., Yedjou, C., Harris SA, Eltom, S., Collins, AR, van Larebeke, N, Gonzalez, Michael J., Weisz, J, Singh, N, Memeo, Lorenzo, Barclay, BJ, Ryan, Elizabeth P., Krishnakumar, PK, Park, Hyun Ho, A. I. Scovassi, Elizabeth P. Ryan, Azqueta, A, Salem, H.K., Van Schooten, FJ, Hu, Z, Salem HK, Calaf, Gloria M, Andrew Ward, Leyns L, Eltom, Sakina E., Park, H. H., Carpenter, DO, Krishnakumar, P., C. Yedjou, Wise, S. S., Carpenter DO, Ratovitski E, Carpenter, O. David, Wolf, T. Gregory, Azqueta, A., Forte, Stefano, Prudhomme, K., Dent P, Blanco Aparicio, C., L. Li, Harris, A. Shelley, Sr, WJP, Chapellier, M., Hamid, A. Roslida, Barclay, Barry J., Carlin, D., M. Vaccari, Po Sing Leung, Po, Sing Leung, Williams, P. Graeme, Woodrick, Jordan, Y. Rojanasakul, Karamouzis, V. Michalis, Berg, A., D. C. Koch, Ann-Karin Olsen, Gulliver L, L. Jian, Prudhomme, K. R., Prudhomme, KR, Ghosh, Paramita M., Dormoy, V, Ryan, E.P., G. Williams, Miousse, I. R., Krishnakumar, P. K, Roy, D., Mehta, R., Cohen Solal, Karine A, Hiroshi Kondoh, Charles, A.K., Wolf, GT, Kirsch Volders, M., Kuemmerle, Nancy B, Romano, Simona, Takemi Otsuki, Miousse, IR, Ochieng, J., Hyun Ho Park, Heneberg, P., Luoping Zhang, Zhang, Luoping, Berg A, Al Mulla F, Goldberg, Gary S, Luqmani, Yunus, Mahara Valverde, Tao Chen, Leandro S. D’Abronzo, Lasfar, A., Castellino RC, Van Schooten, Frederik J., M. Xia, de Cerain Salsamendi, A. L., Karamouzis, Michalis V., Nangami, G., J. E. Klaunig, Sabbisetti, V., Charles, A. K., Ward A, Leung, Po Sing, Corsini, Emanuela, Josiah Ochieng, Martin, Francis L., Christopher, J., C. S. Curran, Francis L. Martin, Barclay, B., Al Temaimi R, Sing Leung P, N. B. Kuemmerle, A. C. Salzberg, Yon Rojanasakul, Miousse, I., Nangia-Makker, P, P. Vadgama, Emilio Rojas, Casey, SC, Raju, Jayadev, Gonzalez, M. J., Casey, S., Carlin, D.J., Ochieng, Josiah, Bay, N. Sarah, Manaf Ali A, Wise JP Sr, Goldberg, GS, J. Sun, M. A. Williams, Zhou, P. Binhua, Blanco-Aparicio, Carmen, Mondello C, S. S. Wise, Rita Nahta, Dong, Chenfang, Nangami, Gladys N, Krishnakumar, P K, A. K. Charles, Langie, S. A. S., Wolf, G., Yasaei, H., R. Ponce Cusi, Ward, A., Ostrosky Wegman, Patricia, Gonzalez, Laetitia, Louis Vermeulen, Felsher, D.W., Hsu, Chia-Wen, Prudhomme, Kalan R., Wolf, Gregory T., Brown, D., Lin Li, Guarnieri T, Romano, MF, Gonzalez L, Chenfang Dong, Marongiu F, Palorini R, Andrade-Vieira, R, Romano, M., Ezio Laconi, Koch, D.C., Nangia Makker P, Moorwood, Kim, Marignani, P., Brunborg, G, P.K. Krishnakumar, Vento, R, Dornetshuber-Fleiss, R, Corsini, E., Hamid, HA, Laird, D. W., Marignani, PA, Rojas E, O. Ogunkua, Amedeo Amedei, Martinez-Leal, Juan Fernando, M. F. Romano, III, GWH, Lowe, Leroy, R. Palorini, Rojas, E, Hamid, H., Laconi E, S. A. Harris, Krishnakumar, P. K., Lin, L-T, Andrade Vieira, Rafaela, Christopher, Joseph A., Yedjou, Clement, Andrew R. Collins, Nuzhat Ahmed, Brown, G. Dustin, W. K. Decker, Lin LT, Prudhomme, R. Kalan, Heneberg P, N. Singh, Memeo L, Hosni K. Salem, Lopez de Cerain Salsamendi, A, Liang-Tzung Lin, Ryan, Elizabeth P, Andrade Vieira R, N. van Larebeke, Roy D, Roy R, Hsue, Yin Hsu, Hideko Sone, Cheng, Qiang, Moorwood, K., Odero Marah, V., Rathmell, W Kimryn, S. Papagerakis, Lopez de Cerain Salsamendi, A., Lowe, L., Ahmed, N, Luanpitpong, S, Salsamendi, Adela Lopez de Cerain, R. B. Robey, Sanderson, T, Chiaradonna F, Bay SN, Binhua P. Zhou, de Cerain Salsamendi, Adela Lopez, Cheng, Qiang (Shawn), Mondello, C., L. Gonzalez, Christopher, J. A., Eltom SE, Goldberg, G.S., Ahmed Lasfar, Kimryn Rathmell, W., Goldberg, G. S., Williams, G, Lasfar, A, Barclay, J. Barry, Sinha, RK, Langie, SA, Mehta R, Hsu, H., Salzberg, Anna C., Memeo, L, Casey, C. Stephanie, I. R. Miousse, R. Di Fiore, Darbre, Philippa, Decker, K. William, Van Schooten, F. J., Xia M, Wade, M., et al., Eriksson, Staffan, Sinha, R., Carpenter, D.O., Blanco Aparicio, Carmen, Naus, C.C., Leyns, Luc, Brooks, SA, Palorini, R, Manjili, Masoud H., Hasiah Ab Hamid, Monica Vaccari, Hsu, HY, Cohen-Solal, Karine A, Li L, Krishnan, H., R. K. Sinha, Cohen Solal KA, Robey, R.Brooks, Yasaei, H, Klaunig, J.E., Ryan EP, Langie, S., Al Mulla, Fahd, Williams, Marc A, Baglole, Carolyn J., A. Colacci, Brooks, S., Prudhomme KR, K. Moorwood, Kravchenko, Julia, Collins, A.R., Blanco-Aparicio, C., Amelia K. Charles, Li, L, Odero Marah V, Scovassi, A.Ivana, Fabio Marongiu, F. Chiaradonna, T. Lee, H. Ab Hamid, Cruickshanks, Nichola, Hu Z., Hsu CW, Castellino, R. C., Pavanello, S., Thompson, Patricia A., Romano, S., W. H. Goodson, J. R. Whitfield, Zhou, BP, Barclay, B.J., F. Darroudi, Mccawley, L. J., G. T. Wolf, Carnero, Amancio, Sinha, R. K., Larebeke, Nik van, Williams, G., Decker, W., Langie, Sabine A. S, Carlin, D. J., Vondráček J, Bisson WH, Ali, A. M., Zhou, B., Decker, WK, L. Lin, Dale W. Laird, Wise, John Pierce, Sr., Ratovitski, E., B. J. Barclay, Li, Lin, Papagerakis, S., P. M. Ghosh, H. Hsu, Lleonart, M, A. Azqueta, W. Engström, Ward, A, Zhang L, Koch, D. C., Marion Chapellier, L. Lowe, Hsu, CW, Joseph A. Christopher, Julia Kravchenko, Brooks, S. A., Kravchenko J, Roman, J, Jesse Roman, Khatami, M., Laird, Dale W, III, Nangami, G, Pavanello, Sofia, Nangami, N. Gladys, L. J. Mccawley, Calaf GM, Martin FL, L. Vermeulen, Shelley A. Harris, Ostrosky Wegman, P., S. Pavanello, Zhou, B.P., Williams, M. A., Eltom, S, Leroy Lowe, III, William H. Goodson, Roy, Debasish, Ryeom, Sandra, Thompson PA, Koppen G, Curran, S. Colleen, Hsu, H-Y, Colacci, A, Vaccari, M., R.Brooks Robey, Rathmell, W.Kimryn, P. Nangia Makker, P. Ostrosky Wegman, Yasaei, Hemad, Koppen, Gudrun, Lasfar, Ahmed, M. J. Gonzalez, Ahmed, N., Daniel C. Koch, Charles, K. Amelia, Ab Hamid H, Narayanan, K., Klaunig, James E., Vadgama, P, Marc A. Williams, Hsu, C.W., Martinez-Leal, J.F., Harris, Shelley A, Chiara Mondello, Harris, S. A., Narayanan, KB, P. Dent, Brown, D. G., Cohen-Solal, A. Karine, Li, L., Laird, DW, Wise, J.P., Sr., Chen, Z., Kuemmerle, B. Nancy, Langie, Sabine A. S., H. H. Park, Eriksson, S., de Cerain Salsamendi, A., Carpenter, David O., G. M. Calaf, Ryeom S, Narayanan KB, A. Lasfar, Brunborg, Gunnar, Sarah N. Bay, P. Heneberg, Castellino, R., Sun J, P. A. Marignani, R. Mehta, Goodson, W., Sabbisetti, V, Ab. Hamid, Hasiah, Williams, Graeme P., Thomas Sanderson, Castellino, RC, Wade M, Robey, R. Brooks, Hu, Zhiwei, Roy, R., W.Kimryn Rathmell, Laird, D., Lleonart ME, William K. Decker, Tae-Jin Lee, Williams, M., D'Abronzo, Leandro S., Wagemaker G, C. Blanco Aparicio, Williams, MA, Romano, S, Hultman, T, Luanpitpong, Sudjit, Zhou, Binhua P., K. A. Cohen Solal, Darroudi, Firouz, Goodson, WH, Williams, Marc A., D’Abronzo, S. Leandro, Marongiu, F., Hamid, Hasiah Ab, Olsen, A. K., Cohen Solal, Karine A., Paul Dent, Hamid, R., Scovassi, A.I., Lee, T. J., Rojas, E., Langie SA, G. S. Goldberg, Roslida A. Hamid, Martin, F.L., Ivana Scovassi, A., Gulliver, L, Kondoh, Hiroshi, Whitfield, J.R., Stefano Forte, Kuemmerle NB, Goodson, W. H., Hsu, C., Simona Romano, Heneberg, P, Charles, Amelia K., van Larebeke N, de Cerain Salsamendi, AL, Marignani, Paola A., Vondráček, Jan, N. Cruickshanks, Weisz, J., Thompson, P, Karamouzis MV, Brown, DG, Wilhelm Engström, Romano, M. F., Otsuki, Takemi, Hsu, Chia Wen, N. Ahmed, R. C. Castellino, R. Abd Hamid, Casey, Stephanie C, E. Corsini, Khatami M, Chen, Tao, Gilbertson, M., Martinez Leal, J., Leyns, L., Amedei A, Papagerakis, Silvana, Sanderson, T., Park, H.H., D'Abronzo, Leandro S, Michalis V. Karamouzis, Kuemmerle, N. B., T. Massfelder, Kirsch-Volders, M, Marongiu, F, S. Romano, Carnero, A., Klaunig, J. E., Barclay, Barry J, Engström, W., Decker, William K, Ab Hamid, H, Sinha, Ranjeet K, Dustin G. Brown, Lee, Tae-Jin, E. Rojas, Ivana Scovassi, A, Vaccari M, Lleonart, M., Prudhomme, Kalan R, Stephanie C. Casey, Darroudi, F, Lee, T-J, Goldberg, Gary S., V. Maguer Satta, Al Mulla, F., Odero Marah, Valerie, Dormoy, Valérian, Maguer Satta, V., P. K. Krishnakumar, Engström W, Olsen, A., Dornetshuber-Fleiss, Rita, Ryeom, S., Kleinstreuer, N, Charles, AK, McCawley, J. Lisa, Wise, SS, Salem, Hosni K., Ogunkua, O., Chen, T., Casey, Stephanie C., David O. Carpenter, T. Otsuki, Cohen-Solal, Karine A., Roy, D, F. J. Van Schooten, Olsen, AK, Lin, Liang-Tzung, L. S. D'Abronzo, Curran CS, Carolyn J. Baglole, Brown, D.G., Al-Mulla, Fahd, Miousse, Isabelle R, Koturbash, I, Krishnakumar, P.K., Robey RB, Roy, R, Rojanasakul, Y., T. Guarnieri, Collins, Andrew Richard, Amedei, A, Darbre, P, Zhiwei Hu, V. Odero Marah, Kim Lyerly, H., Maguer Satta V, Pratima Nangia-Makker, Thompson, Patricia A, L. Zhang, Khatami, Mahin, Lowe, L, Kleinstreuer, N., Zhang, L, Papagerakis S, K. B. Narayanan, Eriksson S, Miousse IR, J. Kravchenko, William H. Bisson, D’Abronzo, Leandro S., Nahta, Rita, J. Vondráček, Baglole, J. Carolyn, Felsher, D. W., Nangami, G.N., V. Sabbisetti, Karine A. Cohen-Solal, M. Gilbertson, Nangami GN, Valerie Odero-Marah, Ostrosky-Wegman, Patricia, Williams, M.A., Wolf GT, Ponce Cusi, Richard, Romano S, Karamouzis, M. V., Adela Lopez de Cerain Salsamendi, D'Abronzo LS, Soucek, Laura, Romano, M.F, Hamid, R. A., Judith Weisz, G. Brunborg, Wise, S., Dormoy V, Cohen Solal, K., Klaunig, James E, Charles, A., M. Khatami, Eriksson, S, Moorwood K, Whitfield, R. Jonathan, Michael Gilbertson, Firouz Darroudi, Jun Sun, Pankaj Vadgama, Rathmell, WK, Zhou, Binhua P, Lleonart, E. Matilde, Koch, D., Wise SS, Sabine A.S. Langie, Koch, DC, Dornetshuber Fleiss, Rita, Hsue-Yin Hsu, Wagemaker, G, Andrade Vieira, R., A. Berg, Wise, J. P., Langie, Sabine a S, Christopher JA, Brooks, Samira A, Luanpitpong S, Carpenter, D. O., J. Weisz, Klaunig, E. James, Koch, Daniel C., Neetu Singh, Raju J, Carpenter, David O, W. K. Rathmell, S. C. Casey, Brooks SA, Martinez Leal JF, Corsini, E, Robey, RB, Brooks Robey, R., S. Eltom, Brunborg G, J. Woodrick, D. J. Carlin, Wolf, G. T., Karamouzis, M., Miousse, Isabelle R., Masoud H. Manjili, Sone, H, Martin, Francis Luke, Charles AK, Valverde, Mahara, Wagemaker, G., Ahmed N, Cruickshanks, N, H. Kim Lyerly, Barclay BJ, Martinez Leal, J. F., M. Lleonart, Vondrá ček, Jan, Castellino, C. Robert, Leyns, L, Hsu HY, Lleonart, Matilde, Whitfield, Jonathan R., Zhenbang Chen, C. J. Baglole, Kirsch Volders M, Mccawley, L., Roman, Jesse, Chiaradonna, F., Dean W. Felsher, Q. S. Cheng, Moon, Eun Yi, Eltom, Sakina E, Krishnan H, P. Darbre, Thierry Massfelder, Koch, C. Daniel, Karamouzis, MV, Vondráček, J., Decker, W. K., Khatami, M, Al Temaimi, Rabeah, Wolf, Gregory T, Gilbertson, M, Carnero, A, Bay, Sarah N., Scovassi, A. Ivana, Bisson, WH, Ryan, E., Kleinstreuer N, Aparicio, Carmen Blanco, Schooten, Frederik J. Van, Salem, HK, Salem, H., Maguer-Satta, Veronique, Colacci, A., E. Laconi, Koturbash I, Moon, E.Y., R. Al Temaimi, Di Fiore, Riccardo, Hamid, Roslida Abd, Juan Fernando Martinez-Leal, Moon, E-Y, Hsu, H.Y., Martin, Francis L, Tae, Jin Lee, Cheng QS, Carmen Blanco-Aparicio, Ryan, EP, Le Jian, Brunborg, G., Manaf Ali, A, Bisson, W., Brown DG, Mehta, Rekha, Al Temaimi, R., Nik van Larebeke, Luqmani, Y., Kravchenko, J, Ratovitski, E, Gonzalez Guzma, Michael J., B. P. Zhou, Laetitia Gonzalez, Naus CC, M. Kirsch Volders, M. Wade, Engström, W, Moon, E., Cheng, Q., Kim Lyerly, H, Wise, J., Kuemmerle, NB, R. Nahta, A. Carnero, Van Schooten, Frederik J, Olugbemiga Ogunkua, Rojanasakul, Y, Sing Leung, Po, Koch DC, Curran, CS, Singh N, Salem, K. Hosni, Langie, SAS, Xia, Menghang, Abdul Manaf Ali, Luanpitpong, S., Patricia Ostrosky-Wegman, Ferdinando Chiaradonna, Darbre P, S. Ryeom, K. R. Prudhomme, William H. Goodson, Nahta, R., Abd Hamid R, Blanco-Aparicio, C, Chiaradonna, Ferdinando, Wade, Mark, Lopez de Cerain Salsamendi A, E. P. Ryan, Moon, E. Y., Sun, J., Maguer-Satta, V, Wise, JP, Ghosh, P. M., Manjili MH, Calaf, Gloria M., Arthur Berg, Wise, S. Sandra, Rafaela Andrade-Vieira, Collins, R. Andrew, Nichola Cruickshanks, Mehta, R, Martin, FL, Castellino, Robert C., Roy, Rabindra, Laura Soucek, Harris, SA, Igor Koturbash, Eun, Yi Moon, Luc Leyns, Chen, Z, Nangia-Makker, Pratima, Philippa Darbre, S. A. S. Langie, Mccawley, Lisa J, Chen, T, Curran, C., Harris, S., Christopher, Joseph A, Barclay, B. J., Mark Wade, Moon, EY, Fahd Al-Mulla, P. Thompson, Cruickshanks, N., Martin, F., Collins AR, Williams MA, Lorenzo Memeo, Danielle J. Carlin, Cheng, QS, Andrade-Vieira, Rafaela, Chia-Wen Hsu, Woodrick J, Mondello, C, Marongiu, Fabio, Manaf Ali, Abdul +999 morecore +2 more sourcesChemical Carcinogenesis [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1976 The first step in the generation of a malignancy seems to be a transformation in the genetic apparatus of a single cell. The ultimate nature of the cancer which appears is a result of the interaction of that change with the control and regulatory apparatus of the whole animal. It appears that the primary cellular change which may be induced by physical,openaire +5 more sourcesHow good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]
, 2005 Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...Denis E. Corpet, Pierre, Fabrice, Pierre, Fabrice H.F., Fabrice Pierre, Corpet, Denis E. +4 morecore +1 more sourceCalcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]
, 2010 Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.Diane Bahuaud, Sylviane Taché, Bahuaud, Diane, Taché, Sylviane, Ossama Allam, Salah Eldin Allam, Ossama, Denis E. Corpet, Pierre, Fabrice, Allam, Ossama, Naud, Nathalie, Pierre, Fabrice H.F., Nathalie Naud, Corpet, Denis E., Fabrice H. F. Pierre +13 morecore +1 more source17Beta-estradiol modulates gastroduodenal preneoplastic alterations in rats exposed to the carcinogen N-methyl-N'-nitro-nitrosoguanidine [PDF]
, 1999 Gastric cancers are a significant cause of morbidity worldwide. Epidemiological studies and animal models show that males have higher incidences of gastric cancers compared with females, suggesting that sex hormones may modulate gastric cancer risk.Reyher, K K, Cromwell, J, Lauwers, G Y, Campbell-Thompson, M, Shiverick, K T +4 morecore +1 more sourceData Quality in Predictive Toxicology: Identification of Chemical Structures and Calculation of Chemical Descriptors
, 2000 Every technique for toxicity prediction and for the detection of structure–activity relationships relies on the accurate estimation and representation of chemical and toxicologic properties.B Pfahringer, Helma, Christoph, Pfahringer, Bernhard, C Helma, S Kramer, Gottmann, E., Kramer, Stefan, Gottmann, Eva, E Gottmann +8 morecore +1 more sourceDehydroalanine and Lysinoalanine in Thermolyzed Casein do not Promote Colon Cancer in the Rat [PDF]
, 2008 Thermolysis of proteins produces xenobiotic amino-acids such as the potentially toxic lysinoalanine, and the alkylating agent, dehydro¬alanine, which have been considered possible health hazards.Bruce, W Robert, Bruce, W. Robert, Archer, Michael C., Taché, Sylviane, Corpet, Denis E., Archer, Michael C +5 morecore +1 more source