Results 41 to 50 of about 83,835 (249)

Mechanism of chemical carcinogenesis [PDF]

, 1992
526-532The mechanism of chemical carcinogenesis induced by different types of compounds such as polycylic aromatics, aromatic amines, tricycloquinazolines, N-nitrosoamines, and halogen compounds, has been discussed.
Gupta, S P
core  

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Supplementary Figure 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Figure 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Cutaneous Chemical Carcinogenesis: Past, Present, And Future

, 1976
Skin tumors chemically induced in mice have provided an important experimental model for studying carcinogenesis and for bioassaying carcinogenic agents.
Hennings, Henry, Saffiotti, Umberto, Yuspa, Stuart H.   +2 more
core   +1 more source

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

Supplementary Figure 2 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Figure 2 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone, Beatrice Cavina, Daniele Gaetano Sirico, Martina Mugnano, Vittorio Bianco, Lisa Miccio, Anna Myriam Perrone, Anna Maria Porcelli, Giuseppe Gasparre, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro   +11 more
wiley   +1 more source

Supplementary Table 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Table 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source