Results 51 to 60 of about 5,905,748 (198)

Thiram Effects on HeLa TI Cells

open access: yesProceedings
Dithiocarbamate pesticides possess a diverse array of molecular mechanisms, making them multifunctional substances [...]
Varvara Maksimova   +5 more
doaj   +1 more source

Mathematical methods and models for radiation carcinogenesis studies [PDF]

open access: yes, 1986
Research on radiation carcinogenesis requires a twofold approach. Studies of primary molecular lesions and subsequent cytogenetic changes are essential, but they cannot at present provide numerical estimates of the risk of small doses of ionizing ...
Kellerer, Albrecht M.
core   +1 more source

Cytotoxicity and transformation of C3H10T1/2 cells induced by areca nut components

open access: yesJournal of the Formosan Medical Association, 2016
Betel quid (BQ) chewing is popular in Taiwan and many other countries. There are about 200–600 million BQ chewers in the world. BQ chewing is one major risk factor of oral cancer and oral submucous fibrosis (OSF).
Chien-Yang Yeh   +8 more
doaj   +1 more source

Mechanism of chemical carcinogenesis [PDF]

open access: yes, 1992
526-532The mechanism of chemical carcinogenesis induced by different types of compounds such as polycylic aromatics, aromatic amines, tricycloquinazolines, N-nitrosoamines, and halogen compounds, has been discussed.
Gupta, S P
core  

Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma

open access: yesCommunications Biology
Hepatocellular carcinoma (HCC) is a molecularly heterogeneous solid malignancy, and its fitness may be shaped by how its tumor cells evolve. However, ability to monitor tumor cell evolution is hampered by the presence of numerous passenger mutations that
Zeynep Kacar   +20 more
doaj   +1 more source

Therapeutic Vulnerabilities of the Key Genetic Drivers in Leiomyosarcoma

open access: yesMedical Sciences
Leiomyosarcoma (LMS) is a rare, aggressive soft-tissue sarcoma arising from smooth muscle cells. It has a high metastatic potential and limited therapeutic options.
Ekaterina A. Lesovaya   +7 more
doaj   +1 more source

Cyclooxygenase-2 Expression in Hamster and Human Pancreatic Neoplasia

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Cyclooxygenase-2 (COX-2) has been implicated in the development of gastrointestinal malignancies. The aim of the present study was to determine COX-2 expression/activity throughout stages of experimental and human pancreatic neoplasia.
Pamela L. Crowell   +5 more
doaj   +1 more source

Evaluation of carcinogenic modes of action for pesticides in fruit on the Swedish market using a text-mining tool

open access: yesFrontiers in Pharmacology, 2014
Toxicity caused by chemical mixtures has emerged as a significant challenge for toxicologists and risk assessors. Information on individual chemicals’ modes of action is an important part of the hazard identification step.
Ilona eSilins   +2 more
doaj   +1 more source

Enantioselective toxicities and carcinogenesis

open access: yes, 2005
In a non-chiral environment, the enantiomers of a racemate possess the same physico-chemical properties but in the biological systems they possess different activities. One of the enantiomers may be more toxic or carcinogenic, and, therefore, the present
Aboul-Enein, Hassan   +2 more
core   +1 more source

Association Study Among Candidate Genetic Polymorphisms and Chemotherapy-Related Severe Toxicity in Testicular Cancer Patients

open access: yesFrontiers in Pharmacology, 2019
Testicular cancer is one of the most commonly occurring malignant tumors in young men with fourfold higher rate of incidence and threefold higher mortality rates in Chile than the average global rates.
María A. Lavanderos   +19 more
doaj   +1 more source

Home - About - Disclaimer - Privacy