Results 71 to 80 of about 83,835 (249)

Prostate carcinogenesis: inflammatory storms

, 2020
Prostate cancer is a major cause of cancer morbidity and mortality. Intra-prostatic inflammation is a risk factor for prostate carcinogenesis, with diet, chemical injury and an altered microbiome being causally implicated.
Guo C., Guo, Christina, De Marzo, Angelo M, De Marzo A. M., Mani R. S., de Bono J. S., Gil, Jesús, Alimonti, Andrea, Sfanos K. S., Alimonti A., Mani, Ram S, Drake, Charles G, Gurel B., de Bono, Johann S, Sfanos, Karen S, Gil J., Gurel, Bora, Drake C. G.   +17 more
core   +1 more source

Globo‐H diagnostic stratification and identification of DUSP14 as a candidate target in colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Colorectal cancer (CRC) is increasingly complicated by drug‐resistant tumors that limit the effectiveness of anticancer therapies. Because resistance mechanisms vary among patients and can evolve over time, personalized treatment strategies are needed.
Keren Zohar, Marco Strecker, Thomas Wartmann, Wenjie Shi, Frederike Stelter, Maximilian Doelling, Mihailo Andric, Or Kakhlon, Christian Täger, Denny Schanze, Michael Linnebacher, Michael Naumann, Daniel E. Stange, Dörthe Jechorek, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Radiation-Induced Mammary Carcinogenesis in Rodent Models: What's Different from Chemical Carcinogenesis?

, 2009
Ionizing radiation is one of a few well-characterized etiologic factors of human breast cancer. Laboratory rodents serve as useful experimental models for investigating dose responses and mechanisms of cancer development.
453152, 453153, 453150, 453151, Shimada, Yoshiya, Nishimura, Mayumi, 柿沼 志津子, 今岡 達彦, 高畠 貴志, Daino, Kazuhiro, 西村 まゆみ, 飯塚 大輔, 453149, 453147, 453148, Kakinuma, Shizuko, 453145, 453146, 453143, 453144, 453141, 453142, 453140, Iizuka, Daisuke, Okamoto, Mieko, 臺野 和広, 島田 義也, Takabatake, Takashi, Imaoka, Tatsuhiko, 453138, 453139, 岡本 美恵子   +31 more
core  

Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.

, 2012
The negative feedback regulation of epidermal growth factor receptor (EGFR) and other tyrosine kinase receptors, including receptor dephosphorylation and endocytosis followed by degradation, is becoming recognized as a major determinant of receptor ...
Dahlhoff, M., Wolf, E., Rose, C., Schneider, M.R., Hrabě de Angelis, M.   +4 more
core   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

Supplementary Table and Figure Legends from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Table and Figure Legends from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source

Associations of Outdoor Air Pollution With Incidence of Cancers Other Than Lung Cancer in a Large US Prospective Cohort

International Journal of Cancer, EarlyView.
Associations between outdoor air pollution and cancers other than lung cancer remain unclear, particularly in the context of tobacco use. Here, the authors assessed possible links between ambient air pollutant exposure and incidence of 20 non‐lung cancers among adults followed over a 25‐year period in the United States.
W. Ryan Diver, Lauren R. Teras, Emily L. Deubler, Alpa V. Patel, Michelle C. Turner   +4 more
wiley   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, EarlyView.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

Chemical Carcinogenesis [PDF]

Nature, 1947
openaire   +3 more sources

Perspective on This Article from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Perspective on This Article from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source