Results 71 to 80 of about 5,905,748 (198)

Chemoprevention of chemical-induced skin cancer by Panax ginseng root extract

Journal of Ginseng Research, 2015
Background: Cancer has emerged as a major health problem globally as a consequence to the increased longevity of the population, changing the environment and life style. Chemoprevention is a new and promising strategy for reducing cancer burden. Recently,
Jyoti Sharma, Pradeep K. Goyal
doaj   +1 more source

Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.

, 2012
The negative feedback regulation of epidermal growth factor receptor (EGFR) and other tyrosine kinase receptors, including receptor dephosphorylation and endocytosis followed by degradation, is becoming recognized as a major determinant of receptor ...
Dahlhoff, M., Wolf, E., Rose, C., Schneider, M.R., Hrabě de Angelis, M.   +4 more
core   +1 more source

Chemical carcinogens [PDF]

, 2020
This chapter is part of the book “Oxford Textbook of Oncology” that gives a whole view of cancer, approaching basic concepts of oncology, etiology, epidemiology, care and characteristics of cancer in specific places. It is focused on chemical carcinogens,
Oliveira, PA, Faustino-Rocha, Ana I
core  

Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.

, 2008
The HMGA1 proteins have a critical role in the process of carcinogenesis. They are overexpressed in most human malignant neoplasias, and the inhibition of their expression has been shown to prevent cell transformation and results in malignant cell death.
Oberyszyn T. M., De Martino I., PALMIERI, DARIO, FUSCO, ALFREDO, Costinean S., Server I. N., Chiappetta G., Visone R., Fedele M., Croce C. M., Kusewitt D. F., Iuliano R.   +11 more
core   +1 more source

Two Perspectives on this Article from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis Model

, 2009
Two Perspectives on this Article from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis ...
Vyomesh Patel (29261), Alfredo A. Molinolo (8878619), Rakefet Czerninski (15092398), J. Silvio Gutkind (90145), Panomwat Amornphimoltham (14889146)   +4 more
core   +1 more source

Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives

Biomolecules
Glucocorticoids (GCs) are routinely used to treat hematological malignancies; however, long-term treatment with GCs can lead to atrophic and metabolic adverse effects.
Ekaterina M. Zhidkova, Evgeniya S. Oleynik, Ekaterina A. Mikhina, Daria V. Stepanycheva, Diana D. Grigoreva, Lyubov E. Grebenkina, Kirill V. Gordeev, Ekaterina D. Savina, Andrey V. Matveev, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya   +10 more
doaj   +1 more source

The first artificial cancer in the internal organs of experimental animals

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
In the world history of cancer research, three achievements in Japan were groundbreaking. First, in 1915, Katsusaburo Yamagiwa and Koichi Ichikawa induced skin cancer on the ears of rabbits by the repeated application of coal tar.
Takao SEKIYA
doaj   +1 more source

Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis. [PDF]

Int J Mol Sci, 2023
Strupp C, Corvaro M, Cohen SM, Corton JC, Ogawa K, Richert L, Jacobs MN.   +6 more
europepmc   +1 more source

Temporal single-cell RNA sequencing dataset of gastroesophagus development from embryonic to post-natal stages

Scientific Data
Gastroesophageal disorders and cancers impose a significant global burden. Particularly, the prevalence of esophageal adenocarcinoma (EAC) has increased dramatically in recent years.
Pon Ganish Prakash, Naveen Kumar, Rajendra Kumar Gurumurthy, Cindrilla Chumduri   +3 more
doaj   +1 more source

Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats. [PDF]

Commun Biol, 2022
Oka K, Fujioka S, Kawamura Y, Komohara Y, Chujo T, Sekiguchi K, Yamamura Y, Oiwa Y, Omamiuda-Ishikawa N, Komaki S, Sutoh Y, Sakurai S, Tomizawa K, Bono H, Shimizu A, Araki K, Yamamoto T, Yamada Y, Oshiumi H, Miura K.   +19 more
europepmc   +1 more source