Results 61 to 70 of about 5,905,748 (198)

Fish consumption, does it beneficially affect markers of colorectal carcinogenesis? [PDF]

, 2009
Background: Fish consumption is possibly associated with a decreased risk of colorectal cancer, as has been shown in several observational studies. However, most of these studies did not discriminate between the effects of oil-rich and lean fish. To date,
Pot, G.K.
core  

Residential ventilation and carcinogenesis [PDF]

, 2016
Recent and emerging research suggests that acute exposure to CO2 levels as low as 1% alters inflammatory and immune signaling pathways independent of extra or intracellular acidosis; including those effectors that are known to be implicated in the ...
Shireesh Apte
core  

Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice

, 2008
Cyclooxoygenase (COX)-2 overexpression is involved in gastric carcinogenesis. While high-salt intake is a known risk factor for gastric cancer development, we determined the effects of high salt on gastric chemical carcinogenesis in COX-2 transgenic (TG)
Wang, X, Wong, CYP, Cheng, ASL, Yu, J, Leung, WK, Chong, WWS, Fan, DM, To, KF, Sung, JJY, Wu, KC, Go, MYY, Chui, Yl, Chan, AWH, Ching, AKK   +13 more
core   +1 more source

Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?

Biomolecules, 2015
The Ras-related C3 botulinum toxin substrate 1 (Rac1) belongs to the family of Ras-homologous small GTPases. It is well characterized as a membrane-bound signal transducing molecule that is involved in the regulation of cell motility and adhesion as well
Gerhard Fritz, Christian Henninger
doaj   +1 more source

Supplementary Figure 1 from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis Model

, 2009
Supplementary Figure 1 from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis ...
Vyomesh Patel (29261), Alfredo A. Molinolo (8878619), Rakefet Czerninski (15092398), J. Silvio Gutkind (90145), Panomwat Amornphimoltham (14889146)   +4 more
core   +1 more source

Medium-term protocols for in vivo evaluation of chemical modifiers of carcinogenesis [PDF]

, 1991
Cancer development is a long-term multistep process which allows interventional measure before the clincial disease emerges. the detection of natural substances which can block the process of carcinogenesis is a important as the identification of anti ...
Camargo, João Lauro Viana de, J. L. V. de Camargo, Camargo, João Lauro Viana de [UNESP]   +2 more
core   +1 more source

Marine-Derived Steroids for Cancer Treatment: Search for Potential Selective Glucocorticoid Receptor Agonists/Modulators (SEGRAMs)

Marine Drugs
Steroids, particularly glucocorticoids, are essential components of cancer treatment for both hematological malignancies and solid tumors.
Ekaterina M. Zhidkova, Ekaterina D. Savina, Ekaterina A. Yurchenko, Ekaterina A. Lesovaya   +3 more
doaj   +1 more source

Prostate carcinogenesis: inflammatory storms

, 2020
Prostate cancer is a major cause of cancer morbidity and mortality. Intra-prostatic inflammation is a risk factor for prostate carcinogenesis, with diet, chemical injury and an altered microbiome being causally implicated.
Guo C., Guo, Christina, De Marzo, Angelo M, De Marzo A. M., Mani R. S., de Bono J. S., Gil, Jesús, Alimonti, Andrea, Sfanos K. S., Alimonti A., Mani, Ram S, Drake, Charles G, Gurel B., de Bono, Johann S, Sfanos, Karen S, Gil J., Gurel, Bora, Drake C. G.   +17 more
core   +1 more source

FBXW7 Targets the SPT6‐ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4‐Nitroquinoline N‐Oxide

MedComm
FBXW7 (F‐box and WD repeat domain‐containing 7) is a classic tumor suppressor that promotes ubiquitylation and degradation of various oncoproteins. Although its tumor suppressor role in many types of cancers has been established, whether and how FBXW7 ...
Jiagui Zhang, Lu Yin, Xiahong You, Xiufang Xiong, Yi Sun   +4 more
doaj   +1 more source

Genetic and Molecular Heterogeneity of Synovial Sarcoma and Associated Challenges in Therapy

Cells
Synovial sarcoma (SS) is one of the most common types of pediatric soft tissue sarcoma (STS) being far less frequent in adults. This STS type is characterized by one specific chromosomal translocation SS18-SSX and the associated changes in signaling ...
Ekaterina A. Lesovaya, Timur I. Fetisov, Beniamin Yu. Bokhyan, Varvara P. Maksimova, Evgeny P. Kulikov, Gennady A. Belitsky, Kirill I. Kirsanov, Marianna G. Yakubovskaya   +7 more
doaj   +1 more source