Results 31 to 40 of about 5,905,748 (198)

Supplementary Figure 2 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Figure 2 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source

Data Quality in Predictive Toxicology: Identification of Chemical Structures and Calculation of Chemical Descriptors [PDF]

, 2000
Every technique for toxicity prediction and for the detection of structure–activity relationships relies on the accurate estimation and representation of chemical and toxicologic properties.
B Pfahringer, Helma, Christoph, Pfahringer, Bernhard, C Helma, S Kramer, Gottmann, E., Kramer, Stefan, Gottmann, Eva, E Gottmann   +8 more
core   +1 more source

Carcinogenicidade do carbendazim e seus metabólitos

Química Nova, 2014
The carcinogenic potential of carbendazim and its metabolites was analyzed using statistical treatment of electronic parameters obtained from DFT/ 6-311++G(d,p) and AM1 calculations.
Renato C. Silva, Karina A. Barros, Antonio C. Pavão   +2 more
doaj   +1 more source

Role of Macrophages in Cytotoxicity, Reactive Oxygen Species Production and DNA Damage in 1,2-Dichloropropane-Exposed Human Cholangiocytes In Vitro

Toxics, 2021
1,2-Dichloropropane (1,2-DCP), a synthetic chlorinated organic compound, was extensively used in the past in offset color proof-printing. In 2014, the International Agency for Research on Cancer (IARC) reclassified 1,2-DCP from its initial Group 3 to ...
Abigail Ekuban, Cai Zong, Frederick Adams Ekuban, Yusuke Kimura, Ryoya Takizawa, Kota Morikawa, Kazuo Kinoshita, Sahoko Ichihara, Seiichiroh Ohsako, Gaku Ichihara   +9 more
doaj   +1 more source

Supplementary Table 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred Hamsters

, 2011
Supplementary Table 1 from A DNA Vaccine against ERBB2 Impairs Chemical Carcinogenesis in Random-Bred ...
Federica Cavallo (380294), Giovanni N. Berta (15095123), Susanna Cappia (15095129), Manuela Iezzi (222621), Paolina Salamone (380292), Barbara Mognetti (5420966), Mauro Papotti (314307), Guido Forni (3209517), Michela Spadaro (3528992), Andrea E. Sprio (15095126), Federica Di Scipio (380291), Piero Musiani (222698)   +11 more
core   +1 more source

Epigenetic targeting of the Nanog pathway and signaling networks during chemical carcinogenesis [PDF]

, 2014
Chemical carcinogenesis has long been synonymous with genotoxicity, which entails DNA damage, genetic mutations and chromosomal abnormalities. The present study investigates a paradigm-shifting model in which epigenetic changes are key contributors to ...
Tommasi, Stella, Besaratinia, Ahmad, Zheng, Albert, Yoon, Jae-In   +3 more
core   +1 more source

Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis

BMC Genomics, 2021
Background Engineered versions of adeno-associated virus (AAV) are commonly used in gene therapy but evidence revealing a potential oncogenic role of natural AAV in hepatocellular carcinoma (HCC) has raised concerns.
Alejandro A. Schäffer, Dana A. Dominguez, Lesley M. Chapman, E. Michael Gertz, Anuradha Budhu, Marshonna Forgues, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Xiaolin Wu, Enkhjargal Bayarsaikhan, Curtis C. Harris, Mathuros Ruchirawat, Eytan Ruppin, Xin Wei Wang   +14 more
doaj   +1 more source

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

eLife, 2019
Lung cancer and chronic lung diseases impose major disease burdens worldwide and are caused by inhaled noxious agents including tobacco smoke. The cellular origins of environmental-induced lung tumors and of the dysfunctional airway and alveolar ...
Magda Spella, Ioannis Lilis, Mario AA Pepe, Yuanyuan Chen, Maria Armaka, Anne-Sophie Lamort, Dimitra E Zazara, Fani Roumelioti, Malamati Vreka, Nikolaos I Kanellakis, Darcy E Wagner, Anastasios D Giannou, Vasileios Armenis, Kristina AM Arendt, Laura V Klotz, Dimitrios Toumpanakis, Vassiliki Karavana, Spyros G Zakynthinos, Ioanna Giopanou, Antonia Marazioti, Vassilis Aidinis, Rocio Sotillo, Georgios T Stathopoulos   +22 more
doaj   +1 more source

Circ_0008657 regulates lung DNA damage induced by hexavalent chromium through the miR-203a-3p/ATM axis

Environment International
Hexavalent chromium [Cr (VI)] is an important environmental pollutant and may cause lung injury when inhaled into the human body. Cr (VI) is genotoxic and can cause DNA damage, although the underlying epigenetic mechanisms remain unclear. To simulate the
Wei Chen, Zehao Chen, Yangyang Jia, Yaozheng Guo, Liting Zheng, Shuwei Yao, Yueting Shao, Meizhen Li, Rulin Mao, Yiguo Jiang   +9 more
doaj   +1 more source

Sawmill Chemicals and Carcinogenesis [PDF]

Environmental Health Perspectives, 2001
Abstract Workers in wood industries are exposed to variable medleys of chemicals, both natural and synthetic. Additional exposures include fungi, bacteria, bark and wood dusts, solvents, paints, and various other wood coatings. These individual and conglomerate exposures have been associated with diverse occupational illnesses and ...
openaire   +3 more sources