Results 11 to 20 of about 5,905,748 (198)

Dose-Response Curves in Chemical Carcinogenesis

open access: yesDose-Response, 2004
Extrapolation from studies of chemical carcinogenicity in rodents, at high doses, to humans, at the typically low doses to which we are exposed, has been one of the most controversial issues in toxicology.
William J. Waddell
doaj   +2 more sources

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]

open access: yes, 2015
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
H. K. Salem   +999 more
core   +4 more sources

Chemical Carcinogenesis [PDF]

open access: yesToxicological Sciences, 2010
Understanding the relationship of chemicals to carcinogenesis has progressed significantly since the initial observations of Hill and Pott in the 1700's. Distinguishing between DNA-reactive chemicals and those which increase cancer risk by increasing cell proliferation has been a major breakthrough in delineating overall mechanisms. Competing processes
Samuel M, Cohen, Lora L, Arnold
openaire   +2 more sources

Chemical Carcinogenesis [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1976
The first step in the generation of a malignancy seems to be a transformation in the genetic apparatus of a single cell. The ultimate nature of the cancer which appears is a result of the interaction of that change with the control and regulatory apparatus of the whole animal. It appears that the primary cellular change which may be induced by physical,
openaire   +5 more sources

Gut dysbiosis in Thai intrahepatic cholangiocarcinoma and hepatocellular carcinoma

open access: yesScientific Reports, 2023
Primary liver cancer (PLC), which includes intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC), has the highest incidence of all cancer types in Thailand.
Yotsawat Pomyen   +21 more
doaj   +1 more source

Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice [PDF]

open access: yes, 2013
Cervical cancer is caused by human papillomavirus (HPV) in collaboration with other non-viral factors. The uterine cervix is hormone responsive and female hormones have been implicated in the pathogenesis of the disease.
Son, Jieun   +3 more
core   +1 more source

Tumor metabolism and associated serum metabolites define prognostic subtypes of Asian hepatocellular carcinoma

open access: yesScientific Reports, 2021
Treatment effectiveness in hepatocellular carcinoma (HCC) depends on early detection and precision-medicine-based patient stratification for targeted therapies.
Yotsawat Pomyen   +8 more
doaj   +1 more source

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

open access: yes, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Diane Bahuaud   +13 more
core   +1 more source

Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

open access: yesEnvironmental Health, 2019
Background Growing evidence indicates that in utero arsenic exposures in humans may increase the risk of adverse health effects and development of diseases later in life. This study aimed to evaluate potential health risks of in utero arsenic exposure on
Panida Navasumrit   +14 more
doaj   +1 more source

Correction to: Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

open access: yesEnvironmental Health, 2019
Following publication of the original article [1], the author reported that incorrect version of Tables 1, 3, 5 and 6 were published.
Panida Navasumrit   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy