Results 11 to 20 of about 2,431 (191)

Carcinogênese gástrica

Clinical and Biomedical Research, 2022
Neste estudo, são revisados tópicos da carcinogênese gástrica, aspectos epidemiológicos, principais fatores de risco e biologia molecular no câncer de estômago.
Eliane de Marco F. Kaminski, Cleber Dario P. Kruel   +1 more
doaj   +2 more sources

Expressão imunohistoquímica de P53 e Ki-67 na carcinogênese esofágica induzida pela dietilnitrosamina: modelo experimental

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar a expressão imunohistoquímica de p53 e ki-67 na carcinogênese esofágica induzida quimicamente através do uso de dietilnitrosamina, em um grupo de 100 camundongos fêmeas.
Miguel Angelo Martins de Castro Junior, Cleber Dario Pinto Kruel, Luise Meurer, Angela Potter de Castro   +3 more
doaj   +2 more sources

Influência da morfina na carcinogênese esofágica induzida pela dietilnitrosamina em ratos – resultados preliminares

Clinical and Biomedical Research, 2022
OBJETIVOS: A alta incidência de câncer esofagiano no norte do Irã foi associada ao ópio. A dietilnitrosamina (DEN) é uma das nitrosaminas com maior potencial de produzir câncer experimental no esôfago.
Carlos F. Dillenburg, Cleber Dario P. Kruel, Tiago Luís D. e Silva, André Silvio Schier, Giancarlo Marafon   +4 more
doaj   +2 more sources

O Papel do Papilomavírus Humano na Carcinogênese Bucal

Revista Brasileira de Cancerologia, 2007
Os estudos realizados nos últimos anos com auxílio de novas tecnologias de detecção viral permitem considerar o papilomavírus humano como um agente causal do câncer de colo de útero. Além da interação com as regiões genitais, outros sítios anatômicos têm
Luciana Estevam Simonato, Glauco Issamu Miyahara   +1 more
doaj   +3 more sources

Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms. [PDF]

Hemasphere, 2021
Mutations in the calreticulin (CALR) gene are seen in about 30% of essential thrombocythemia and primary myelofibrosis patients. To address the contribution of the human CALR mutants to the pathogenesis of myeloproliferative neoplasms (MPNs) in an endogenous context, we modeled the CALRdel52 and CALRins5 mutants by induced pluripotent stem cell (iPSC ...
Secardin L, Gomez Limia C, da Silva-Benedito S, Lordier L, El-Khoury M, Marty C, Ianotto JC, Raslova H, Constantinescu SN, Bonamino MH, Vainchenker W, Monte-Mor B, Di Stefano A, Plo I.   +13 more
europepmc   +2 more sources

HLA-B Serine 116 Confers Protection Against Severe COVID-19 in a Cohort From Rio de Janeiro, Brazil. [PDF]

HLA
ABSTRACT COVID‐19 is a respiratory disease caused by SARS‐CoV‐2, in which severe outcomes are primarily driven by an exacerbated immune response. The HLA region has been extensively investigated in COVID‐19 due to its central role in the immune response, although genetic associations vary across populations.
Pereira MADS, Ferreira SN, Gonçalves CCA, Reis MCD, Zampier CDP, Leitão IC, Lopes MSA, Rossi AD, Soares-Lima SC, Galliez RM, Barroso SPC, Junior ODCF, Tanuri A, Castiñeiras TMPP, Rossi ÁD, Cardoso CC.   +15 more
europepmc   +2 more sources

Insights into the Oncogenic, Prognostic, and Immunological Role of BRIP1 in Pan‐Cancer: A Comprehensive Data‐Mining‐Based Study

Journal of Oncology, Volume 2023, Issue 1, 2023., 2023
Background. BRCA1 interacting helicase 1 (BRIP1), an ATP‐dependent DNA helicase which belongs to an Iron‐Sulfur (Fe‐S) helicase cluster family with a DEAH domain, plays a key role in DNA damage and repair, Fanconi anemia, and development of several cancers including breast and ovarian cancer.
Yongru Liu, Xi Wu, Yunlu Feng, Qingwei Jiang, Shengyu Zhang, Qiang Wang, Aiming Yang, Yanqing Liu   +7 more
wiley   +1 more source

The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal Cancers. [PDF]

Biomed Res Int, 2019
GI tumors represent a heterogeneous group of neoplasms concerning their natural history and molecular alterations harbored. Nevertheless, these tumors share very high incidence and mortality rates worldwide and patients’ poor prognosis. Therefore, the identification of specific biomarkers could increase the development of personalized medicine, in ...
Meireles Da Costa N, Ribeiro Pinto LF, Nasciutti LE, Palumbo A.   +3 more
europepmc   +2 more sources

Potential Therapeutic Effects of Underground Parts of Kalanchoe gastonis-bonnieri on Benign Prostatic Hyperplasia. [PDF]

Evid Based Complement Alternat Med, 2019
Benign Prostatic Hyperplasia (BPH) affects mainly older men. It is estimated to affect 50% of 51‐60‐year‐old men and 70% of 61‐70‐year‐old men. BPH is a nonmalignant proliferation of epithelial and stromal cells of the prostate gland regions. Despite the use of conventional pharmacological therapy, herbal medicines are used in BPH therapy, and several ...
Palumbo A, Casanova LM, Corrêa MFP, Da Costa NM, Nasciutti LE, Costa SS.   +5 more
europepmc   +2 more sources

Mecanismo da carcinogênese do câncer de próstata através do consumo de carne vermelha: Revisão de literatura [PDF]

, 2017
A estimativa em 2016 para novos casos de câncer de próstata no brasil foi de 61.000 casos com 12.215 óbitos, diminuição de 11,6% à incidência da doença em 2015.
Alex Pereira Ramos, Priscila Paiva dos Santos, Lívia Soares Viana, Pedro Carvalho Nogueira, Eduardo de Souza Sampaio Diniz, Alcendino de Almeida   +5 more
core   +3 more sources