Results 141 to 150 of about 317,890 (399)

Metalloporphyrin/Phthalocyanine Catalysts for Electrocatalytic Nitrogen Fixation

open access: yesAdvanced Science, EarlyView.
This review focuses on the application of metal porphyrin/phthalocyanine‐based catalysts in electrocatalytic nitrogen fixation. The detailed examination encompasses the structure and modification strategies of metal porphyrin/phthalocyanine‐based catalysts, their application in electrocatalytic nitrogen fixation, and the associated reaction mechanisms.
Hai Sun   +6 more
wiley   +1 more source

Binding occupational exposure limits for carcinogens in the EU – good or bad?

open access: yesScandinavian Journal of Work, Environment & Health, 2019
The European Union (EU) has increased its efforts to counteract cancer due to occupational exposure. This is done by several means, including more active use and revision of the Carcinogen Directive (1), launch of the Roadmap on Carcinogens (2) and the ...
Gunnar Johanson, Håkan Tinnerberg
doaj   +1 more source

Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]

open access: yes, 1994
Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L.   +2 more
core  

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning   +11 more
wiley   +1 more source

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li   +8 more
wiley   +1 more source

Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang   +7 more
wiley   +1 more source

Retrospective on U.S. Health Risk Assessment: How Others Can Benefit [PDF]

open access: yes, 1995
Dr. Paustenbach reviews the scientific underpinnings of about twenty years of health risk assessment practice and their implications for environmental policy.
Paustenbach, Dennis J.
core   +1 more source

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