Results 171 to 180 of about 94,370 (316)

Aristolochic Acid and Alternative Lengthening of Telomeres Mechanisms Underlie Liver Angiosarcoma Pathogenesis. [PDF]

Liver Cancer
Chen TW, Hsu C, Lee JC, Chang K, Huang SC, Chu HC, Chen CH, Tsai YC, Hsueh FJ, Kuo CH, Hsu CL, Cheng AL.   +11 more
europepmc   +1 more source

Carcinogens are Mutagens: Their Detection and Classification

, 1973
Bruce N. Ames
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Parasitic Infections and Carcinogenesis: Molecular Mechanisms, Immune Modulation, and Emerging Therapeutic Strategies. [PDF]

Oncol Res
Pawłowska M, Jarek D, Milanowski J, Szewczyk-Golec K.   +3 more
europepmc   +1 more source

The risk of developing non-carcinogenic effects in children in industrial city in multicompartment contamination with chemical pollutants

, 2020
Андрей Геннадьевич Сетко, Ж.К. K. Мрясова, E.A. Terekhova, А.В. V. Тюрин   +3 more
openalex   +2 more sources

Data from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure <i>In Utero</i>

, 2023
Kevin Hochstenbach, Danitsja M. van Leeuwen, Hans Gmuender, Ralf W. Gottschalk, Martinus Løvik, Berit Granum, Unni C. Nygaard, Ellen Namork, Micheline Kirsch‐Volders, Ilse Decordier, Kim Vande Loock, Harrie Besselink, Margareta Törnqvist, Hans von Stedingk, Per Rydberg, Jos Kleinjans, Henk Van Loveren, Joost H.M. van Delft   +17 more
openalex   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

<i>N</i>,<i>N'</i>,<i>N''</i>-Tris(β-hydroxyethyl)hexahydro-1,3,5-triazine: MAK Value Documentation, addendum - Translation of the German version from 2023. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission https://www.dfg.de/de/ueber-uns/gremien/senat/arbeitsstoffe/mitglieder.   +1 more
europepmc   +1 more source

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Is Indoor Air Pollution the Missing Link Between Radon and Lung Cancer? Rethinking Epidemiological Support for the LNT Model. [PDF]

Dose Response
Lee DH.
europepmc   +1 more source