Results 1 to 10 of about 34,592 (264)

The application of KI.C57-ras2.0 mouse in the carcinogenicity evaluation of medical devices—carcinogenicity evaluation of a novel hemodialyzer [PDF]

open access: yesAnnals of Medicine
Introduction Alternative transgenic mouse models, such as rasH2, have been developed as to replace the traditional 2-year rodent carcinogenicity study.
Han Wang   +10 more
doaj   +2 more sources

The potential relationship of tattoo ink with lymphoma and skin malignancies: an overview

open access: yesКлинический разбор в общей медицине
Introduction. Tattooing has gone from traditional tribal traditions to widespread modern practice nowadays. The practice of tattooing has undergone social transformations that have led to increased health risks in the short and long term.
Vitaly B. Kaliberdenko   +7 more
doaj   +1 more source

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

open access: yesFrontiers in Toxicology
The rodent cancer bioassays are conducted for agrochemical safety assessment yet they often do not inform regulatory decision-making. As part of a collaborative effort, the Rethinking Carcinogenicity Assessment for Agrochemicals Project (ReCAAP ...
Amber Goetz   +5 more
doaj   +1 more source

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup

open access: yesFrontiers in Toxicology
Introduction: The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) initiated a process in 2012 to revise the S1B Guideline “Testing for Carcinogenicity of Pharmaceuticals”.
Todd Bourcier   +9 more
doaj   +1 more source

Corrigendum: Mequindox Induced Genotoxicity and Carcinogenicity in Mice

open access: yesFrontiers in Pharmacology, 2018
Qianying Liu   +14 more
doaj   +1 more source

Corrigendum: Association Between Night-Shift Work and Cancer Risk: Updated Systematic Review and Meta-Analysis

open access: yesFrontiers in Oncology, 2020
Aishe Dun   +6 more
doaj   +1 more source

Organ accumulation and carcinogenicity of highly dispersed multi-walled carbon nanotubes administered intravenously in transgenic rasH2 mice

open access: yesInternational Journal of Nanomedicine, 2019
Atsushi Sobajima,1 Hisao Haniu,1,2 Hiroki Nomura,1 Manabu Tanaka,1 Takashi Takizawa,1 Takayuki Kamanaka,1 Kaoru Aoki,1,3 Masanori Okamoto,1 Kazushige Yoshida,1 Jun Sasaki,1 Kumiko Ajima,2 Chika Kuroda,1,2 Haruka Ishida,2 Satomi Okano,2 Katsuya Ueda,2 ...
Sobajima A   +16 more
doaj  

A new database contains 520 studies investigating the carcinogenicity data of 238 pharmaceuticals across 14 ATC classifications

open access: yesFrontiers in Toxicology
Panagiotis G. Karamertzanis   +6 more
doaj   +1 more source

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