Results 11 to 20 of about 230,259 (343)

Pulmonary toxicity, genotoxicity, and carcinogenicity evaluation of molybdenum, lithium, and tungsten: A review.

open access: yesToxicology, 2022
Molybdenum, lithium, and tungsten are constituents of many products, and exposure to these elements potentially occurs at work. Therefore it is important to determine at what levels they are toxic, and thus we set out to review their pulmonary toxicity ...
N. Hadrup, J. Sørli, A. Sharma
semanticscholar   +1 more source

Final review of the Séralini <em>et al</em>. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology [PDF]

open access: yesEFSA Journal, 2012
On 19 September 2012, Séralini et al. published online in the scientific journal Food and Chemical Toxicology a publication describing a 2-year feeding study in rats investigating the health effects of genetically modified maize NK603 with and without ...
European Food Safety Authority
doaj   +1 more source

Effects of Prenatal Exposure to Aflatoxin B1: A Review

open access: yesMolecules, 2021
Aflatoxins are mycotoxins produced as secondary fungal metabolites. Among them, aflatoxin B1 (AFB1) stands out due to its genotoxic and mutagenic potential, being a potent initiator of carcinogenesis.
João Victor Batista da Silva   +2 more
doaj   +1 more source

DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation

open access: yesFrontiers in Artificial Intelligence, 2021
Carcinogenicity testing plays an essential role in identifying carcinogens in environmental chemistry and drug development. However, it is a time-consuming and label-intensive process to evaluate the carcinogenic potency with conventional 2-years rodent ...
Ting Li   +4 more
semanticscholar   +1 more source

Detection of Associations Between Diseases in Animal Carcinogenicity Experiments

open access: yes, 1989
Detection of Associations Between Diseases in Animal Carcinogenicity ...
Turnbull, B., Mitchell, T.
core   +5 more sources

Oxidative Stress in the Carcinogenicity of Chemical Carcinogens [PDF]

open access: yesCancers, 2013
This review highlights several in vivo studies utilizing non-genotoxic and genotoxic chemical carcinogens, and the mechanisms of their high and low dose carcinogenicities with respect to formation of oxidative stress. Here, we survey the examples and discuss possible mechanisms of hormetic effects with cytochrome P450 inducers, such as phenobarbital, a-
Anna Kakehashi   +3 more
openaire   +2 more sources

A Novel Strategy to Predict Carcinogenicity of Antiparasitics Based on a Combination of DNA Lesions and Bacterial Mutagenicity Tests

open access: yesFrontiers in Public Health, 2017
Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction.
Qianying Liu   +7 more
doaj   +1 more source

Genotoxicity and carcinogenicity of herbal products [PDF]

open access: yes, 2017
In 2012, the World Health Organization (WHO) recorded 14 million new cases of cancer and 8.2 million cancer-related deaths. Remarkably, the WHO estimates that 30 % of cancer mortalities are due to lifestyle choices and environmental factors that can and ...
Duez, Pierre   +9 more
core   +3 more sources

Benzene histotoxic and teratogenic Effects in exposed Mice

open access: yesKufa Journal for Veterinary Medical Sciences, 2017
Throughout the last two decades, benzene was a prominent source of an occupational and environmental pollution in Iraq. Especially from direct contact with private electric generators which were installed closer to homes or even inside every home in ...
Hussamadin kadhim   +4 more
doaj   +1 more source

A quantitative risk assessment of sinonasal cancer as a function of time in workers occupationally exposed to wood dust

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2021
Objectives The aim of this study is to conduct a quantitative assessment of the risk related to occupational exposure to wood dust and the occurrence of sinonasal epithelial cancer (SNEC) by histotype, depending on the duration of exposure, using ...
Renata Soćko
doaj   +1 more source

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