Results 21 to 30 of about 34,592 (264)

Benzene histotoxic and teratogenic Effects in exposed Mice

open access: yesKufa Journal for Veterinary Medical Sciences, 2017
Throughout the last two decades, benzene was a prominent source of an occupational and environmental pollution in Iraq. Especially from direct contact with private electric generators which were installed closer to homes or even inside every home in ...
Hussamadin kadhim   +4 more
doaj   +1 more source

Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]

open access: yesEFSA Journal, 2013
Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj   +1 more source

What Applied Physical Chemistry Can Contribute to Understanding Cancer: Toward the Next Generation of Breakthroughs

open access: yesAppliedChem, 2023
Living systems, whether healthy or diseased, must obey the laws of chemistry. The purpose of this review is to identify the interpretive limits of cellular biochemistry using, largely, the tools of physical chemistry.
Parker Schanen, Howard R. Petty
doaj   +1 more source

The Carcinogenicity of Chromium [PDF]

open access: yesEnvironmental Health Perspectives, 1981
The carcinogenicity of chromium compounds is reviewed with specific attention to the gaps in knowledge for risk estimation and research needs. The most important problems at present are whether trivalent chromium compounds cause cancer, and whether there is a difference in cancer causing effects between the soluble and the slightly soluble hexavalent ...
openaire   +2 more sources

Challenging Global Waste Management – Bioremediation to Detoxify Asbestos

open access: yesFrontiers in Environmental Science, 2020
As the 21st century uncovers ever-increasing volumes of asbestos and asbestos-contaminated waste, we need a new way to stop ‘grandfather’s problem’ from becoming that of our future generations.
Shannon L. Wallis   +11 more
doaj   +1 more source

Are there thresholds for carcinogens carcinogenicity?

open access: yesMycotoxins, 2008
魚や肉などの焼けこげに含まれている2-amino-3,8-dimethylimidazo[4,5-f ] quinoxaline(MeIQx)のラット肝臓における低用量発がん性を中期発がん性試験法で検討した.その結果,MeIQx?DNA 付加体形成は微量からみられ,より高い用量で8-hydroxy-2′-deoxyquanosine 形成,lacI 遺伝子変異,イニシエーション活性等が誘発された.また,肝臓の前腫瘍性病変であるglutahione S-transferase placental(GST-P)陽性細胞巣は,さらにより高い用量で誘発された.N- ニトロソ化合物であるN-nitrosodiethylamine やN-nitrosodimethylamine でもGST-P ...
FUKUSHIMA, Shoji   +3 more
openaire   +2 more sources

Prediction of ADME-Tox properties and toxicological endpoints of triazole fungicides used for cereals protection

open access: yesADMET and DMPK, 2019
Within this study we have considered 9 triazole fungicides that are approved to be used in European Union for protecting cereals: cyproconazole, epoxiconazole, flutriafol, metconazole, paclobutrazole, tebuconazole, tetraconazole, triadimenol and ...
Ionut Mădălin Gridan   +2 more
doaj   +1 more source

Relevant Aspects of Drug Genetic Toxicology

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2022
Genotoxic lesions are not only a cause of genetic pathologies and cancer, but also the most common and significant factor of the etiopathology of cardiovascular and neurodegenerative disorders, reproductive losses, infertility, and aging.
A. D. Durnev, A. K. Zhanataev
doaj   +1 more source

Study on the chronic toxicity and carcinogenicity of iron-based bioabsorbable stents

open access: yesNanotechnology Reviews, 2023
Fe-based stents have been made a figure in biodegradable stents by their good mechanical capacity and biocompatibility, appropriate strength–ductility combination. Although the iron corrosion rate was not ideal, which had been optimized by iron alloy and
Shi Xiaoli   +8 more
doaj   +1 more source

Mutagenic and/or carcinogenic compounds in meat and meat products: Heterocyclic aromatic amines perspective

open access: yesТеория и практика переработки мяса, 2022
Meat and meat products, which have a very important place in terms of nutrition, can endanger human health if they are not properly prepared and preserved. Meat and meat products except for products such as sushi, which are deliberately consumed raw, are
E. Oz, F. Oz
doaj   +1 more source

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