Results 21 to 30 of about 230,259 (343)
Molecules, 2022 Read-across applies the principle of similarity to identify the most similar substances to represent a given target substance in data-poor situations. However, differences between the target and the source substances exist.
Edoardo Luca Viganò +6 more
doaj +1 more source
Biocompatibility and Carcinogenicity of Carbon Nanotubes as Biomaterials
Nanomaterials, 2020 With the development of nanotechnology in recent years, there have been concerns about the health effects of nanoparticles. Carbon nanotubes (CNTs) are fibrous nanoparticles with a micro-sized length and nano-sized diameter, which exhibit excellent ...
Kaoru Aoki, N. Saito
semanticscholar +1 more source
Carcinogenicity of aspartame, methyleugenol, and isoeugenol
, 2023 Carcinogenicity of aspartame, methyleugenol, and ...
JC Corton (17861876) +44 more
core +1 more source
CARCINOGENICITY OF FATS 'BROWNED' BY HEATING.
, 1954 CARCINOGENICITY OF FATS 'BROWNED' BY ...
ARDELLE CATHERINE. LANE (7961999)
core +3 more sources
Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]
EFSA Journal, 2013 Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj +1 more source
The Carcinogenicity of Chromium [PDF]
Environmental Health Perspectives, 1981 The carcinogenicity of chromium compounds is reviewed with specific attention to the gaps in knowledge for risk estimation and research needs. The most important problems at present are whether trivalent chromium compounds cause cancer, and whether there is a difference in cancer causing effects between the soluble and the slightly soluble hexavalent ...
openaire +2 more sources
AppliedChem, 2023 Living systems, whether healthy or diseased, must obey the laws of chemistry. The purpose of this review is to identify the interpretive limits of cellular biochemistry using, largely, the tools of physical chemistry.
Parker Schanen, Howard R. Petty
doaj +1 more source
Making better use of toxicity studies for human health by extrapolating across endpoints
ALTEX: Alternatives to Animal Experimentation, 2020 To develop and evaluate scientifically robust and innovative approaches for the safety assessment of chemicals across multiple regulatory sectors, the EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has started a project to ...
Federica Madia +4 more
doaj +1 more source
Are there thresholds for carcinogens carcinogenicity?
Mycotoxins, 2008 魚や肉などの焼けこげに含まれている2-amino-3,8-dimethylimidazo[4,5-f ] quinoxaline（MeIQx）のラット肝臓における低用量発がん性を中期発がん性試験法で検討した．その結果，MeIQx?DNA 付加体形成は微量からみられ，より高い用量で8-hydroxy-2′-deoxyquanosine 形成，lacI 遺伝子変異，イニシエーション活性等が誘発された．また，肝臓の前腫瘍性病変であるglutahione S-transferase placental（GST-P）陽性細胞巣は，さらにより高い用量で誘発された．N- ニトロソ化合物であるN-nitrosodiethylamine やN-nitrosodimethylamine でもGST-P ...
FUKUSHIMA, Shoji +3 more
openaire +2 more sources
ADMET and DMPK, 2019 Within this study we have considered 9 triazole fungicides that are approved to be used in European Union for protecting cereals: cyproconazole, epoxiconazole, flutriafol, metconazole, paclobutrazole, tebuconazole, tetraconazole, triadimenol and ...
Ionut Mădălin Gridan +2 more
doaj +1 more source