Results 91 to 100 of about 113,709 (339)

Revision of ICH S8 Needed?

open access: yesFrontiers in Toxicology, 2022
Jan Willem Van Der Laan
doaj   +1 more source

The Failure of Agency-Forcing: The Regulation of Airborne Carcinogens Under Section 112 of the Clean Air Act [PDF]

open access: yes, 1985
Professor Graham analyzes section 112 of the Clean Air Act, a provision intended by Congress to achieve ambitious regulatory ends by constraining agency discretion.
Graham, John D.
core   +2 more sources

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

A screening method for ranking chemicals by their fate and behaviour in the environment and potential toxic effects in humans following non-occupational exposure [PDF]

open access: yes, 2004
A large number of chemicals are released intentionally or unintentionally into the environment each year. These include thousands of substances that are currently listed worldwide and several hundred new substances added annually (Mücke et al., 1986 ...
Capelton, A   +2 more
core  

Hierarchically Porous Nitrogen‐Doped Carbon with High Conductivity for Rapid and Efficient Cr(VI) Reduction

open access: yesAdvanced Science, EarlyView.
The d‐PNC(1100, 10%) catalyst, synthesized via a zinc‐based ionic liquid self‐sacrificing pore‐forming strategy to create a defect‐rich, hierarchical, nitrogen‐doped porous structure, enhances conductivity, promotes rapid mass transfer and synergistic catalytic activity, driving efficient Cr(VI) reduction in OA solution to generate Cr(III)‐OA complexes.
Danyan Lin   +7 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Occupational Exposure to Inhalable and Respirable Wood Dust of Pedunculate Oak (Quercus robur L.) in a Furniture Factory

open access: yesBioResources, 2022
Given the well-known carcinogenicity of hardwood dust, occupational exposure to oak wood dust has been determined in a furniture factory on different wood processing machines during sanding, planing, and milling.
Anka Ozana Čavlović   +6 more
doaj  

Biocompatible Magnetopyroelectric Composite Films for Cell Stimulation

open access: yesAdvanced Science, EarlyView.
Magnetopyroelectric films couple Fe3O4 nanoparticles with pyroelectric P(VDF‐TrFE) to turn alternating magnetic fields into controlled heat and pyroelectric currents. This heavy‐metal free platform safely boosts neural progenitor cells differentiation via synergistic thermal and pyroelectrical cues, engages AKT and calcium pathways, and opens practical
Hao Ye   +11 more
wiley   +1 more source

Ochratoxin A: 50 Years of Research

open access: yesToxins, 2016
Since ochratoxin A (OTA) was discovered, it has been ubiquitous as a natural contaminant of moldy food and feed. The multiple toxic effects of OTA are a real threat for human beings and animal health.
Frantisek Malir   +4 more
doaj   +1 more source

Supplementary Table from Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma

open access: gold, 2023
Marzia Scortegagna   +7 more
openalex   +1 more source

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