Results 41 to 50 of about 34,330 (305)
Ecotoxicology and Environmental Safety, 2022 The genotoxicity, development toxicity, carcinogenicity, and acute or chronic toxic effects of glutaraldehyde (GA), particularly during occupational exposure through its use as a fixative, disinfectant, and preservative, are well-documented but its ...
Ha-Na Oh +4 more
doaj +1 more source
Global gene expression analysis in the liver of mice administered carcinogens and non-carcinogens For the development of a new rapid and reliable carcinogenicity test [PDF]
, 2017 Although much has been elucidated about the mechanism of cellular carcinogenesis, evaluation of the carcinogenicity of substances is still difficult. Since a number of new synthetic materials for drugs and food have been developed, it is necessary to ...
古倉 聡 +2 more
core
EURL ECVAM Recommendation on the Cell Transformation Assay based on the Bhas 42 cell line [PDF]
, 2013 The carcinogenic potential of compounds is a crucial aspect in human hazard and risk assessment of substances. Among the various alternatives developed for carcinogenicity prediction, the cell transformation assays (CTAs) have been shown to closely model
AMCOFF SVEN PATRIK +3 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]
, 1993 A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core +2 more sources
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Proposed criteria for the evaluation of the scientific quality of mandatory rat and mouse feeding trials with whole food/feed derived from genetically modified plants [PDF]
, 2016 In recent years, animal feeding trials conducted with whole food/feed have been a focal issue in the controversy on the safety assessment of genetically modified (GM) plants and derived food/feed.
Custers, René +9 more
core +1 more source
Advanced Functional Materials, EarlyView.Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida +16 more
wiley +1 more source
Genes and Environment, 2023 Background Carcinogenic risk assessment studies have been repeatedly improved and are still being debated to find a goal. Evaluation might be changed if new approaches would be applied to some chemicals which means that new approaches may change the ...
Masami Yamada +3 more
doaj +1 more source
Selective Benzene Capture by Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.Metal‐organic frameworks (MOFs) hold significant potential for capturing benzene from air emissions and hydrocarbon mixtures in liquid phases. This capability stems from their precisely engineered structures, versatile chemistries, and diverse binding interactions.
Zongsu Han +4 more
wiley +1 more source