Results 41 to 50 of about 34,758 (354)

Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells

Microorganisms, 2021
Therapeutic DNA-vaccination against drug-resistant HIV-1 may hinder emergence and spread of drug-resistant HIV-1, allowing for longer successful antiretroviral treatment (ART) up-to relief of ART.
Maria Isaguliants, Olga Krotova, Stefan Petkov, Juris Jansons, Ekaterina Bayurova, Dzeina Mezale, Ilze Fridrihsone, Athina Kilpelainen, Philip Podschwadt, Yulia Agapkina, Olga Smirnova, Linda Kostic, Mina Saleem, Oleg Latyshev, Olesja Eliseeva, Anastasia Malkova, Tatiana Gorodnicheva, Britta Wahren, Ilya Gordeychuk, Elizaveta Starodubova, Anastasia Latanova   +20 more
doaj   +1 more source

Global gene expression analysis in the liver of mice administered carcinogens and non-carcinogens For the development of a new rapid and reliable carcinogenicity test [PDF]

, 2017
Although much has been elucidated about the mechanism of cellular carcinogenesis, evaluation of the carcinogenicity of substances is still difficult. Since a number of new synthetic materials for drugs and food have been developed, it is necessary to ...
古倉 聡, 水島 かつら, 高木 智久   +2 more
core  

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA [PDF]

, 2010
Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns.
Jamie E. Jennings-Gee, Mariana Tozlovanu, Richard Manderville, Mark Steven Miller, Annie Pfohl-Leszkowicz, Gary G. Schwartz, O’Brien, Pfohl-Leszkowicz, Reddy, Krogh, Stoev, Chernozemsky, Pfohl-Leszkowicz, Castegnaro, Huyghe, Schwartz, Ueta, Raymond, Mantle, Mantle, Pfohl-Leszkowicz, Petkova-Bocharova, Petkova-Bocharova, Satoh, Manderville, Faucet, Gillman, Molinié, Nguyen, Petkova-Bocharova, Faucet-Marquis, Frenette, Pfohl-Leszkowicz, Mantle, Pfohl-Leszkowicz, Pinelli, El Adlouni, Petkova-Bocharova, Pfohl-Leszkowicz, Verma, Kamataki, Gustafsson, Atanasova, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Dimitrov, Møller, Bay, Bose, Solti, Patil, Lei   +52 more
core   +3 more sources

Engineered Mycelial Scaffolds With Tunable Ultraviolet Protection, Wettability, Thermal Stability, and Spatial Mechanics

Advanced Engineering Materials, EarlyView.
Fungal mycelia grown into biodegradable scaffolds and infused with titania nanoparticles show enhanced ultraviolet shielding, thermal protection, and surface nonwettability. Properties were tuned by drying methods, revealing structure–function relationships.
Juwon S. Afolayan, Xin Zhang, Carole C. Perry   +2 more
wiley   +1 more source

Characteristics of Medical Products Comprising Human Cells, Genes, or Tissues Developed in Japan and the European Union Compared via Public Assessment Reports

Frontiers in Bioengineering and Biotechnology, 2020
Medical products comprising human cells, genes, and tissues have been developed for clinical applications worldwide, and their developmental environment has been established.
Ryosuke Kurauchi, Ryosuke Kurauchi, Hiroi Kasai, Tatsuya Ito   +3 more
doaj   +1 more source

Developmental neurotoxicity induced by glutaraldehyde in neuron/astrocyte co-cultured cells and zebrafish

Ecotoxicology and Environmental Safety, 2022
The genotoxicity, development toxicity, carcinogenicity, and acute or chronic toxic effects of glutaraldehyde (GA), particularly during occupational exposure through its use as a fixative, disinfectant, and preservative, are well-documented but its ...
Ha-Na Oh, Donggon Yoo, Seungmin Park, Sangwoo Lee, Woo-Keun Kim   +4 more
doaj   +1 more source

Impact of Sustainable Binders Based on Lignin and Collagen on the Volume Stability and Mechanical Properties of MgO‐C Refractories with MgO‐C Recyclates

Advanced Engineering Materials, EarlyView.
Collagen hydrolysate is evaluated as a sustainable binder for MgO‐C refractories. Its thermally induced cross‐linking and gas release lead to expansion and cracking in large bricks, but tailored batches with lignin, recyclates, or fine graphite improve the gas release while thermal treatment and stability.
Till M. J. Stadtmüller, Florian Kerber, Kirsten Moritz, Steffen Dudczig, Konstantin Kraushaar, Thomas Schemmel, Jana Hubálková, Patrick Gehre, Christos G. Aneziris   +8 more
wiley   +1 more source

EURL ECVAM Recommendation on the Cell Transformation Assay based on the Bhas 42 cell line [PDF]

, 2013
The carcinogenic potential of compounds is a crucial aspect in human hazard and risk assessment of substances. Among the various alternatives developed for carcinogenicity prediction, the cell transformation assays (CTAs) have been shown to closely model
AMCOFF SVEN PATRIK, CORVI Raffaella, GRIESINGER Claudius, WHELAN Maurice   +3 more
core   +1 more source

Development of Sustainable MgO–C Refractories Using MgO–C Recyclates and a Novel Eco‐Friendly Fructose–Tannin Binder Crosslinked With Citric Acid

Advanced Engineering Materials, EarlyView.
This study develops sustainable MgO–C refractories using recycled materials and eco‐friendly fructose–tannin binders. The enhanced performance of citric acid as a cross‐linker and functional additives on mechanical and thermomechanical properties was examined. Characterization included strength tests, immersion trials, and microstructural and inclusion
Dinesh K. Gunasekar, Jana Hubálková, Steffen Dudczig, Gert Schmidt, Florian Kerber, Thomas Schemmel, Patrick Gehre, Christos G. Aneziris   +7 more
wiley   +1 more source

Significant Subgraph Mining with Multiple Testing Correction [PDF]

, 2015
The problem of finding itemsets that are statistically significantly enriched in a class of transactions is complicated by the need to correct for multiple hypothesis testing.
Borgwardt, Karsten M., Kasenburg, Niklas, López, Felipe Llinares, Sugiyama, Mahito   +3 more
core   +1 more source