Results 31 to 40 of about 33,845 (314)
Advanced Materials Design for Adsorption of Toxic Substances in Cigarette Smoke
Advanced Science, 2023 Cigarettes, despite being economically important legal consumer products, are highly addictive and harmful, particularly to the respiratory system. Tobacco smoke is a complex mixture containing over 7000 chemical compounds, 86 of which are identified to ...
Ting Zeng +7 more
doaj +1 more source
Alternative Models for Carcinogenicity Testing [PDF]
Toxicological Sciences, 2001 The International Conference on Harmonisation Expert Working Group on Safety suggested that under certain circumstances, data from alternative assays could be used in safety evaluation in place of a second bioassay. Several alternatives were discussed.
S M, Cohen, D, Robinson, J, MacDonald
openaire +2 more sources
Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]
, 2017 Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena +9 more
core +1 more source
Can a simple test in bacteria identify cancer-causing chemicals in humans?
BJHS ThemesSince the 1950s, US officials have sought to reduce cancer incidence by regulating chemical exposures. However, rodent carcinogenicity tests are lengthy and expensive, making it impractical to identify carcinogens among the tens of thousands of chemicals
Angela N. H. Creager
doaj +1 more source
EFSA Journal, 2015 The EFSA Panel on Food additives and Nutrient Sources added to Food (ANS Panel) provides a scientific opinion re‐evaluating the safety of ascorbic acid (E 300), sodium ascorbate (E 301) and calcium ascorbate (E 302) as food additives. The use of ascorbic
EFSA Panel on Food additives and Nutrient Sources added to Food (ANS)
doaj +1 more source
Vaccines, 2023 In Italy, cervical cancer represents the fifth most prevalent cancer in women under 50 years of age and is one of the most commonly detected lesions globally.
Miriam Gorgone +7 more
doaj +1 more source
A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines
Natural Product Communications, 2016 Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, increasing number of case ...
Ahmet Aydιn +2 more
doaj +1 more source
Selection of an in vitro carcinogenicity test for derivatives of the carcinogen hexamethylphosphoramide [PDF]
British Journal of Cancer, 1977 The demonstration that hexamethylphosphoramide (HMPA) possesses potent carcinogenic properties has raised doubts about the safety of exposure to other phosphoric amides. In order to define a suitable short-term test with which to evaluate such analogues, the response of the Salmonella typhimurium mutation assay of Ames and cell transformation assay of ...
J, Ashby, J A, Styles, D, Anderson
openaire +2 more sources
Global gene expression analysis in the liver of mice administered carcinogens and non-carcinogens For the development of a new rapid and reliable carcinogenicity test [PDF]
, 2017 Although much has been elucidated about the mechanism of cellular carcinogenesis, evaluation of the carcinogenicity of substances is still difficult. Since a number of new synthetic materials for drugs and food have been developed, it is necessary to ...
古倉 聡 +2 more
core
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source