Results 31 to 40 of about 14,534 (309)

Rates of Primary and Secondary Prevention of Cervical Cancer: A Study in a Province in the South of Italy

open access: yesVaccines, 2023
In Italy, cervical cancer represents the fifth most prevalent cancer in women under 50 years of age and is one of the most commonly detected lesions globally.
Miriam Gorgone   +7 more
doaj   +1 more source

Selection of an in vitro carcinogenicity test for derivatives of the carcinogen hexamethylphosphoramide [PDF]

open access: yesBritish Journal of Cancer, 1977
The demonstration that hexamethylphosphoramide (HMPA) possesses potent carcinogenic properties has raised doubts about the safety of exposure to other phosphoric amides. In order to define a suitable short-term test with which to evaluate such analogues, the response of the Salmonella typhimurium mutation assay of Ames and cell transformation assay of ...
J, Ashby, J A, Styles, D, Anderson
openaire   +2 more sources

Towards achieving a modern science-based paradigm for agrochemical carcinogenicity assessment

open access: yes, 2023
The rodent cancer bioassay has been the standard approach to fulfill regulatory requirements for assessing human carcinogenic potential of agrochemicals, industrial chemicals and pharmaceuticals.
LUIJTEN Mirjam   +4 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines

open access: yesNatural Product Communications, 2016
Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, increasing number of case ...
Ahmet Aydιn   +2 more
doaj   +1 more source

Synthetic crude oils carcinogenicity screening tests. Quarterly report, October 16, 1978--February 15, 1979

open access: yes, 1979
Four crude oils (Southern Louisiana Crude Petroleum, H. Coal Syncrude, Paraho Crude Shale Oil, and Geokinetics in situ Shale Oil) have been distilled into four fractions (naphtha, mid-distillate, gas oil, and residue) for analysis and biological ...
King, C. F.   +4 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

open access: yesAdvanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir   +5 more
wiley   +1 more source

In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse

open access: yesGenes and Environment, 2023
Background tert-Butyl hydroperoxide (TBHP; CAS 75–91-2), a hydroperoxide, is mainly used as a polymerization initiator to produce polyethylene, polyvinyl chloride, and unsaturated polyester.
Yasumasa Murata   +10 more
doaj   +1 more source

Cost-effectiveness of short-term tests for carcinogenicity

open access: yes, 1986
Most chemicals to which we are exposed are not properly tested for carcinogenicity. The latest methods of in vitro testing provide a way of screening with sufficient accuracy to remedy this situation.
Lester B Lave (5455793)   +1 more
core   +1 more source

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