Results 31 to 40 of about 14,534 (309)
In Italy, cervical cancer represents the fifth most prevalent cancer in women under 50 years of age and is one of the most commonly detected lesions globally.
Miriam Gorgone +7 more
doaj +1 more source
Selection of an in vitro carcinogenicity test for derivatives of the carcinogen hexamethylphosphoramide [PDF]
The demonstration that hexamethylphosphoramide (HMPA) possesses potent carcinogenic properties has raised doubts about the safety of exposure to other phosphoric amides. In order to define a suitable short-term test with which to evaluate such analogues, the response of the Salmonella typhimurium mutation assay of Ames and cell transformation assay of ...
J, Ashby, J A, Styles, D, Anderson
openaire +2 more sources
Towards achieving a modern science-based paradigm for agrochemical carcinogenicity assessment
The rodent cancer bioassay has been the standard approach to fulfill regulatory requirements for assessing human carcinogenic potential of agrochemicals, industrial chemicals and pharmaceuticals.
LUIJTEN Mirjam +4 more
core +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines
Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, increasing number of case ...
Ahmet Aydιn +2 more
doaj +1 more source
Four crude oils (Southern Louisiana Crude Petroleum, H. Coal Syncrude, Paraho Crude Shale Oil, and Geokinetics in situ Shale Oil) have been distilled into four fractions (naphtha, mid-distillate, gas oil, and residue) for analysis and biological ...
King, C. F. +4 more
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir +5 more
wiley +1 more source
Background tert-Butyl hydroperoxide (TBHP; CAS 75–91-2), a hydroperoxide, is mainly used as a polymerization initiator to produce polyethylene, polyvinyl chloride, and unsaturated polyester.
Yasumasa Murata +10 more
doaj +1 more source
Cost-effectiveness of short-term tests for carcinogenicity
Most chemicals to which we are exposed are not properly tested for carcinogenicity. The latest methods of in vitro testing provide a way of screening with sufficient accuracy to remedy this situation.
Lester B Lave (5455793) +1 more
core +1 more source

