Results 21 to 30 of about 14,534 (309)

Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats

open access: yesParticle and Fibre Toxicology, 2022
Background A mounting number of studies have been documenting the carcinogenic potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have evaluated the pulmonary carcinogenicity of MWCNTs in vivo.
Motoki Hojo   +20 more
doaj   +1 more source

Studies on the degranulation test for carcinogens [PDF]

open access: yesFEBS Letters, 1983
The radiometric assay of degranulation of the hepatic endoplasmic reticulum by chemical carcinogens has been re‐examined. Both 1,2,3,4,‐ and 1,25,6‐dibenzanthracenes caused degranulation of rough membranes in vitro; with acetamidofluorenes and naphthylamines the carcinogenic analogues caused moderately greater degranulation.
Poole, Thomas W., Parke, Dennis V.
openaire   +2 more sources

Predicting carcinogenicity by using batteries of dependent short-term tests

open access: yes, 1994
Among the various methods for predicting carcinogenicity from a battery of short-term tests (STTs), the carcinogenicity prediction and battery selection (CPBS) procedure is the most prominent.
Kim, B S, Margolin, B H
core   +1 more source

Efficiency of age-adjusted tests in animal carcinogenicity experiments.

open access: yes, 1985
Carcinogenicity experiments may be analysed by a simple comparison of the control and exposed groups with respect to the proportions of observed tumors amongst dead animals, when longevity is identical in control and exposed groups.
Ryan, LM
core   +1 more source

Advanced Materials Design for Adsorption of Toxic Substances in Cigarette Smoke

open access: yesAdvanced Science, 2023
Cigarettes, despite being economically important legal consumer products, are highly addictive and harmful, particularly to the respiratory system. Tobacco smoke is a complex mixture containing over 7000 chemical compounds, 86 of which are identified to ...
Ting Zeng   +7 more
doaj   +1 more source

Alternative Models for Carcinogenicity Testing [PDF]

open access: yesToxicological Sciences, 2001
The International Conference on Harmonisation Expert Working Group on Safety suggested that under certain circumstances, data from alternative assays could be used in safety evaluation in place of a second bioassay. Several alternatives were discussed.
S M, Cohen, D, Robinson, J, MacDonald
openaire   +2 more sources

A Model for Selecting Short-Term Tests of Carcinogenicity

open access: yes, 2018
A theoretical model is presented that selects among available short term tests of carcinogenicity and then classifies chemicals on the basis of the results.
Glen Dranoff (5455859)   +3 more
core   +1 more source

Can a simple test in bacteria identify cancer-causing chemicals in humans?

open access: yesBJHS Themes
Since the 1950s, US officials have sought to reduce cancer incidence by regulating chemical exposures. However, rodent carcinogenicity tests are lengthy and expensive, making it impractical to identify carcinogens among the tens of thousands of chemicals
Angela N. H. Creager
doaj   +1 more source

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs

open access: yes, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
R. R. Shen   +31 more
core   +1 more source

Scientific Opinion on the re‐evaluation of ascorbic acid (E 300), sodium ascorbate (E 301) and calcium ascorbate (E 302) as food additives

open access: yesEFSA Journal, 2015
The EFSA Panel on Food additives and Nutrient Sources added to Food (ANS Panel) provides a scientific opinion re‐evaluating the safety of ascorbic acid (E 300), sodium ascorbate (E 301) and calcium ascorbate (E 302) as food additives. The use of ascorbic
EFSA Panel on Food additives and Nutrient Sources added to Food (ANS)
doaj   +1 more source

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