Chronic exposure to combined carcinogens enhances breast cell carcinogenesis with mesenchymal and stem-like cell properties. [PDF]
PLoS ONE, 2014 Breast cancer is the most common type of cancer affecting women in North America and Europe. More than 85% of breast cancers are sporadic and attributable to long-term exposure to small quantities of multiple carcinogens.
Lenora Ann Pluchino +1 more
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Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
eLife, 2021 Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari +12 more
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BMC Cancer, 2021 Introduction Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) – including chronic myeloid leukemia (CML) – and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are largely clinically distinct
K. A. Mundt +7 more
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Updated fraction of cancer attributable to lifestyle and environmental factors in Denmark in 2018
Scientific Reports, 2022 Environmental exposures and avoidable risk factors account for a large proportion of cancer burden. Exposures and lifestyle vary over time and between populations, which calls for updated and population-specific quantification of how various avoidable ...
Anne Julie Tybjerg +5 more
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Unraveling Therapeutic Opportunities and the Diagnostic Potential of microRNAs for Human Lung Cancer
Pharmaceutics, 2023 Lung cancer is a major public health problem and a leading cause of cancer-related deaths worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer patients remains low, emphasizing the urgent need for innovative ...
Osama Sweef +8 more
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Triple primary lung cancer: a case report
BMC Pulmonary Medicine, 2022 Background The risk of developing lung cancer is increased in smokers, patients with chronic obstructive pulmonary disease, individuals exposed to environmental carcinogens, and those with a history of lung cancer.
Hye Sook Choi, Ji-Youn Sung
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Co-carcinogenesis: Human Papillomaviruses, Coal Tar Derivatives, and Squamous Cell Cervical Cancer
Frontiers in Microbiology, 2017 Cervical cancer (CC) is the fourth most common cancers among women worldwide. Human papillomaviruses (HPVs) play a major role in the etiology of CC, with several lines of epidemiologic and experimental evidence supporting a role for non-viral (co ...
Harry W. Haverkos +2 more
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Synergistic cancer risk assessment from PM1 bound metals and PAHs in the Indo-Gangetic Region
Sustainable Chemistry for the Environment, 2023 The atmospheric particulate matter (PM) contains a significant amount of human carcinogens such as metals and Polycyclic Aromatic Hydrocarbons (PAHs).
Aman Deep Gupta +2 more
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Genetic Reprogramming of Human Mammary Cells by Environmental Carcinogens Released into Breast Milk
CHIMIA, 2008 Epidemiologic studies indicate that high serum levels of chlorinated pollutants such as dioxins or pesticides constitute a risk factor for breast cancer in postmenopausal women.
Ramiro Dip +4 more
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Safety and Health at Work, 2012 Malignant mesothelioma is an uncommon but rapidly fatal disease for which the principal aetiological agent is exposure to asbestos. Mesothelioma is of particular significance in Australia where asbestos use was very widespread from the 1950s until the ...
Ewan MacFarlane +3 more
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