Results 11 to 20 of about 3,644,428 (241)

Application of the Key Characteristics of Carcinogens to Per and Polyfluoroalkyl Substances

International Journal of Environmental Research and Public Health, 2020
Per- and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally persistent chemicals used in industrial and consumer products. Human exposure to PFAS is extensive, and PFAS contamination has been reported in drinking water and food
A. Temkin, B. A. Hocevar, David Q. Andrews, O. Naidenko, L. Kamendulis   +4 more
semanticscholar   +1 more source

Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

eLife, 2021
Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari, Albert Kuo, YiFan Zhang, Lu Li, Kamel Lahouel, Ludmila Danilova, Alexander Favorov, Thomas A Rosenquist, Arthur P Grollman, Ken W Kinzler, Leslie Cope, Bert Vogelstein, Cristian Tomasetti   +12 more
doaj   +1 more source

Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016

Occupational and Environmental Medicine, 2020
Objectives This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study.
Tim Lesley Kyle Sally Kurt Degu Omar Dilaram Mohsen Fa Driscoll Rushton Steenland Hutchings Straif Abate
semanticscholar   +1 more source

Inequalities in Environmental Cancer Risk and Carcinogen Exposures: A Scoping Review

International Journal of Environmental Research and Public Health, 2023
Background: Cancer is the leading cause of death in Canada and a major cause of death worldwide. Environmental exposure to carcinogens and environments that may relate to health behaviors are important to examine as they can be modified to lower cancer ...
Kristian Larsen, E. Rydz, Cheryl E Peters   +2 more
semanticscholar   +1 more source

Updated fraction of cancer attributable to lifestyle and environmental factors in Denmark in 2018

Scientific Reports, 2022
Environmental exposures and avoidable risk factors account for a large proportion of cancer burden. Exposures and lifestyle vary over time and between populations, which calls for updated and population-specific quantification of how various avoidable ...
Anne Julie Tybjerg, Søren Friis, Katrina Brown, Mef Christina Nilbert, Lina Morch, Brian Køster   +5 more
doaj   +1 more source

The importance of evaluating specific myeloid malignancies in epidemiological studies of environmental carcinogens

BMC Cancer, 2021
Introduction Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) – including chronic myeloid leukemia (CML) – and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are largely clinically distinct
K. A. Mundt, L. D. Dell, P. Boffetta, E. M. Beckett, H. N. Lynch, V. J. Desai, C. K. Lin, W. J. Thompson   +7 more
doaj   +1 more source

The mutational signature profile of known and suspected human carcinogens in mice

Nature Genetics, 2020
Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analyzing tumor genomes from mice chronically exposed to 1 of 20 known or suspected human carcinogens, we reveal ...
L. Riva, A. Pandiri, Y. R. Li, A. Droop, J. Hewinson, M. Quail, V. Iyer, Rebecca Shepherd, R. Herbert, P. Campbell, R. Sills, L. Alexandrov, A. Balmain, D. Adams   +13 more
semanticscholar   +1 more source

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis.

Carcinogenesis, 2015
The purpose of this review is to stimulate new ideas regarding low-dose environmental mixtures and carcinogens and their potential to promote invasion and metastasis.
J. Ochieng, G. Nangami, Olugbemiga Ogunkua, I. Miousse, Igor Koturbash, V. Odero-Marah, L. Mccawley, P. Nangia-Makker, N. Ahmed, Y. Luqmani, Zhenbang Chen, S. Papagerakis, Gregory T Wolf, Chenfang Dong, Binhua P. Zhou, Dustin G. Brown, A. Colacci, R. A. Hamid, C. Mondello, Jayadev Raju, E. Ryan, Jordan Woodrick, A. Scovassi, Neetu Singh, M. Vaccari, R. Roy, S. Forte, L. Memeo, H. Salem, A. Amedei, R. Al-Temaimi, F. Al-Mulla, William H. Bisson, Sakina E. Eltom   +33 more
semanticscholar   +1 more source

Unraveling Therapeutic Opportunities and the Diagnostic Potential of microRNAs for Human Lung Cancer

Pharmaceutics, 2023
Lung cancer is a major public health problem and a leading cause of cancer-related deaths worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer patients remains low, emphasizing the urgent need for innovative ...
Osama Sweef, Elsayed Zaabout, Ahmed Bakheet, Mohamed Halawa, Ibrahim Gad, Mohamed Akela, Ehab Tousson, Ashraf Abdelghany, Saori Furuta   +8 more
doaj   +1 more source

Triple primary lung cancer: a case report

BMC Pulmonary Medicine, 2022
Background The risk of developing lung cancer is increased in smokers, patients with chronic obstructive pulmonary disease, individuals exposed to environmental carcinogens, and those with a history of lung cancer.
Hye Sook Choi, Ji-Youn Sung
doaj   +1 more source